Search results (757 results)

Mar 6 2025 by Gerardo - Montante Montelongo, MD

Fundus photograph of an 83-year-old male with a history of Diabetes, smoking, cataract surgery on the right eye in 2022, and open-angle glaucoma. Asymptomatic. Indirect ophthalmoscopy revealed 80% excavation, peripapillary atrophy, and a hyperpigmented perifoveal lesion with 35% atrophy, 10% drusen, and 5.1 mm diameter, corresponding to a CHRPE. At multimodal imaging, FFA shows hypoautofluorescence of the lesion, OCT shows preservation of internal retinal layers, atrophy of external retinal layer, with an RPE disruption, and posterior shadowing. USG shows a flat hyperechoic lesion 5.1 mm in diameter and 1.32 mm in thickness, solid and with high internal reflectance.

Photographer: Gerardo Montante-Montelongo, MD, Mexican Institute of Ophthalmology

Imaging device: Clarus 700

Condition/keywords: congenital hypertrophy of the retinal pigment epithelium (CHRPE)multimodal imaging

Jan 27 2025 by Vishal Agrawal, MD, FRCS,FACS,FASRS

16 year-old male patient presented with DOV, nyctalopia and nystagmus. Fundus revealed pigment clumping, pale disc and preserved para-arteriolar retinal pigment epithelium (PPRPE) in both eyes. Genetic testing revealed CRB1 gene mutation.

Photographer: Dr Ayushi Gupta

Imaging device: Clarus 700

Condition/keywords: retinitis pigmentosa

Jan 27 2025 by Vishal Agrawal, MD, FRCS,FACS,FASRS

16 year-old male patient presented with DOV, nyctalopia and nystagmus. Fundus revealed pigment clumping, pale disc and preserved para-arteriolar retinal pigment epithelium (PPRPE) in both eyes. Genetic testing revealed CRB1 gene mutation.

Photographer: Dr Ayushi

Imaging device: Clarus 700

Condition/keywords: retinitis pigmentosa

Jan 7 2025 by Drew Mitchell

Fundus Autofluorescence of a CHRPE and Bear Tracks.

Photographer: Drew Mitchel, OCT-C

Imaging device: Optos Silverstone

Condition/keywords: bear tracksCHRPEcongenital hypertrophy of the retinal pigment epithelium (CHRPE)

Jan 5 2025 by César Adrián Gómez Valdivia, MD

Hamartoma of the retina and retinal pigment epithelium found in a 10 year-old male patient with type 2 neurofibromatosis history. Overlaying fibrous proliferation can be appreciated. Findings were unilateral.

Photographer: @eyemissu2

Imaging device: TOPCON TRC-50DX

Condition/keywords: hamartomaretinal pigment epithelium (RPE) hamartoma

Oct 10 2024 by Virginia Gebhart

56 year old male with new amelanotic melanoma emanating from the ciliary body through the posterior iris epithelium. CT scan showed no evidence of metastatic disease. Pt scheduled for radioactive plaque and tumor biopsy

Photographer: Virginia Gebhart, Retina Consultants of Carolina

Imaging device: Samsung Galaxy

Condition/keywords: amelanotic melanomairis melanoma

Sep 6 2024 by Giriraj Vibhute

Fundus photo and autofluorescence image in a 58-year-old woman A&B: Right and left eye ultrawidefield pseudocolor imaging in case of congenital hypertrophy of RPE. C&D: Fundus autofluorescence of right and left eye of the same patient. The patient/ family members did not have any history of colon cancer. Patient was advised colonoscopy and family members were screened.

Photographer: Giriraj Vibhute, dept of retina, M M Joshi eye institute, Hubli. India

Imaging device: Optos daytona

Condition/keywords: bear trackscongenital hypertrophy of the retinal pigment epithelium (CHRPE)

Aug 27 2024 by Monica Elena Cortizo Brown , MD

9 year old girl with pendular nystagmus, photophobia and a fundus photo that shows clear view of the choroidal vasculature due to the hypopigmentation of retinal pigment epithelium.

Photographer: Mónica Cortizo Brown , Hospital de la Luz, Ciudad de México

Condition/keywords: nystagmusocular albinismoculocutaneous albinismphotophobia

Jul 25 2024 by Navneet Mehrotra, DNB

Fundus photograph of a 17 year old boy with sudden decrease in vision in his left eye. Retinal pigment epithelial changes were noticed at the macula.

Photographer: Navneet Mehrotra

Imaging device: Nidek

Condition/keywords: retinal pigment epithelium (RPE) changes

May 26 2024 by shama sharief

Funds photo with CHRPE and CHRRPE.

Condition/keywords: CHRRPEcongenital hypertrophy of the retinal pigment epithelium (CHRPE)

May 23 2024 by ARVIND JAIN M

Bilateral involving CHRRPE lesion in a 26 year old gentleman who came with complains of defective vision in both eyes since childhood. His BCVA was Right eye 5/60 and left eye 6/60. His anterior segment examination showed no abnormality with posterior segment examination showed both eyes (Fig.1a and 1b) greyish white elevated lesion involving the macula with thick fibrotic membrane causing the macular drag temporally in right eye and supero-temporally in left eye. (Fig.2a and 2b) OCT showing the thick ERM with the disorganized inner retinal layers suggestive of hamartoma of the Retina and Retinal Pigment Epithelium.

Photographer: Dr. Arvind Jain M, MBBS,MS Ophthal, FVRS

Condition/keywords: CHRRPE

May 13 2024 by Gabrielle Hallai

Electrooculogram responses on the left from a control individual with no known retinal pathology. There is a clear dark trough around 13 minutes (arrow down) and a light peak around 25 minutes (arrow up). The Arden ratio, or the light peak to dark trough ratio, is 2.54, indicative of normal retinal pigment epithelium function (normal > 1.80, abnormal < 1.65). On the right-hand side, there is a representative image from an individual with Best macular dystrophy. Note the reduced responses for both the dark and light phase. There is a reduced Arden ratio of 1.23, suggestive of abnormal retinal pigment epithelium function. An abnormal Arden ratio is universal in Best vitelliform macular dystrophy and is the most common electroretinographic change in this disease. Other bestrophinopathies such as autosomal recessive bestrophinopathy may have normal EOG. EOG testing was completed on the Diagnosys ColorDome.

Photographer: Gabrielle Hallai, PhD, Cleveland Clinic Cole Eye Institute

Imaging device: Diagnosys ColorDome

Condition/keywords: Best diseaseelectrooculogramelectroretinographyEOG

May 8 2024 by KANWALJEET HARJOT MADAN, M.S. (Ophthalmology), FAICO (Vitreous - Retina)

These are the fundus pics of a 28 year young male who presented with history of night blindness. Fundus examintaion revealed presence of Choroideremia. There is diffuse pigment clumping followed by atrophy of retinal pigment epithelium, photoreceptors and choriocapillaris with visible sclera and choroidal vessels in this condition. Atrophy progresses centripetally and the fovea is the last to become affected.

Photographer: Dr. Kanwaljeet Harjot Madan

Imaging device: Zeiss Clarus

Condition/keywords: choriocapillarischoroideremianightblindness

Apr 24 2024 by Marcelo Zas, MD PhD

Best vitelliform macular dystrophy (BVMD) or Best disease. Is the most common autosomal dominant macular dystrophy. It involves the retinal pigment epithelium (RPE), and leads to a characteristic bilateral yellow “egg-yolk” appearance of the macula as you can see in this image. Essentially, BVMD is considered to have 6 clinical stages: Previtelliform, Vitelliform, Pseudohypopyon, Vitelleruptive, Atrophic and Choroidal neovascularization. As the disease progresses, patients may experience a slow, bilateral decrease in visual acuity, central scotoma, or metamorphopsia. With secondary CNV, visual decline can be rapid, however.

Photographer: Luciano Scorsetti MD

Condition/keywords: Macular Dystrophy

Apr 22 2024 by Angela Rico

59 year-old female with MM1 Mitochondrial Genetic Defect. V/A- OD: 20/25, OS:20/40

Photographer: Angela Rico M.D.

Condition/keywords: Dystrophy of the Retinal Pigment Epithelium

Apr 15 2024 by Virginia Gebhart

29 year old male with multiple flat CHRPE lesions, genetic testing negative for ACP genes associated with Gardner syndrome. Multiple intraretinal amelanotic lesions consistent with Benign Lobular Inner Nuclear Layer Proliferations (BLIP) of the retina

Photographer: Virginia Gebhart

Imaging device: Topcon

Condition/keywords: BLIP Benign Lobular Inner Nuclear Layer ProliferationsCHRPEcongenital hypertrophy of the retinal pigment epithelium (CHRPE)

Apr 2 2024 by José Laércio Araújo Filho

Fundus photograph of a 36-year-old man with a Hamartoma of the retinal pigment epithelium.

Photographer: José Laércio de Araújo Filho, Universidade de São Paulo, São Paulo

Imaging device: Optos Daytona P200T / A10600

Condition/keywords: retinal pigment epithelium (RPE) hamartoma

Apr 2 2024 by José Laércio Araújo Filho

Fundus photograph of a 36-year-old man with a Hamartoma of the retinal pigment epithelium.

Photographer: José Laércio de Araújo Filho, Universidade de São Paulo, São Paulo

Imaging device: Optos Daytona P200T / A10600

Condition/keywords: hamartoma

Mar 28 2024 by Houda Brarou

Fundus photograph of a 35 years old woman with a familial drusen which is characterized by the presence of small yellow-white accumulations of extracellular material under the retinal pigment epithelium in the ocular posterior pole,

Photographer: Houda brarou, Mohammed V military hospital of Rabat, Morocco

Imaging device: TOPCON DRI OCT Triton Plus

Condition/keywords: familial drusen

Feb 21 2024 by Nikhil K Bommakanti, MD

A monocular man in his sixties presented with blurred vision in the right eye for two months. Optical coherence tomography demonstrated vitreous cells and characteristic inflammatory deposits of the outer retina and retinal pigment epithelium, and laboratory testing confirmed the diagnosis of syphilis. He was admitted for intravenous penicillin and consultation with a specialist in infectious diseases.

Condition/keywords: syphilis

Nov 10 2023 by Virginia Gebhart

17-year-old male with multiple pigmented spots most likely related to Gardner's Syndrome. Pt has not been diagnosed with FAP at this time, however pt receives regular screenings. Extensive maternal family hx of FAP syndrome and colon cancer. Pt's mother has FAP, who had colon resection. Pt's 2 aunts, 1 uncle, grandmother and great grandmother all passed from colon cancer. Pt has multiple maternal cousins diagnosed with FAP

Photographer: Virginia Gebhart

Imaging device: Topcon

Condition/keywords: CHRPEcongenital hypertrophy of the retinal pigment epithelium (CHRPE)familial adenomatous polyposisGardner Syndrome

Oct 21 2023 by Aditya S Kelkar, MS, FRCS, FASRS,FRCOphth

Right eye fundus photograph of a 83 year old female demonstrating Disciform Scar And Retinal Pigment Epithelium (RPE) Detachment In A Case Of Idiopathic Polypoidal Choroidal Vasculopathy (IPCV).

Photographer: DR APURVA MUKADAM

Imaging device: OPTOS DAYTONA

Condition/keywords: disciform scar

Sep 12 2023 by Ben Serar

Fundus photograph of the LE showing an irregular, yellow-white, juxtapapillary, choroidal lesion with well-defined geographic borders; with diffuse and mottled depigmentation of the overlying pigment epithelium; and multiple small vascular networks on the tumor surface.

Condition/keywords: choroidal osteoma

Sep 12 2023 by Ben Serar

Fundus photograph of the RE showing an irregular, yellow-white, juxtapapillary, choroidal lesion with well-defined geographic borders; with diffuse and mottled depigmentation of the overlying pigment epithelium; and multiple small vascular networks on the tumor surface.

Condition/keywords: choroidal osteoma

Aug 8 2023 by Navneet Mehrotra, DNB

A 20 year old female presented with decreased vision and metamorphopsia noticed in her left eye for one year. Other eye was normal. BCVA was 6/12 in her left eye.

Photographer: Dharti, Retina Care , Ahmedabad

Condition/keywords: Combined pigment epithelial and retinal hamartoma