Search results (766 results)

Jun 26 2025 by Hector Gabriel Moreno Solano, MD, MHA

High-resolution OCT of the right eye shows a localized disruption of the retinal pigment epithelium (RPE)–Bruch’s membrane complex, consistent with a choroidal rupture. There is loss of the normal outer retinal architecture over the lesion, with focal elevation and irregularity of the underlying RPE. Hyperreflective material is noted at the level of the break, without associated subretinal fluid or signs of active choroidal neovascularization.

Photographer: Hector Gabriel Moreno Solano, Instituto Mexicano de Oftalmología “IMO I.A.P”

Imaging device: REVO

Condition/keywords: Choroidal Rupture, OCT

Jun 26 2025 by Hector Gabriel Moreno Solano, MD, MHA

Fundus autofluorescence imaging of the right eye shows three hypoautofluorescent linear lesions located temporally to the fovea, consistent with choroidal ruptures. The lesions demonstrate sharply demarcated borders with variable surrounding hyperautofluorescence, suggestive of retinal pigment epithelium (RPE) disruption and potential remodeling. One rupture is located near the foveal region, though the foveal center remains spared.

Photographer: Hector Gabriel Moreno Solano, Instituto Mexicano de Oftalmología “IMO I.A.P”

Imaging device: CLARUS

Condition/keywords: autofluorescence imaging, Choroidal Rupture

Jun 26 2025 by Hector Gabriel Moreno Solano, MD, MHA

Color fundus photograph of the right eye reveals three well-defined, curvilinear choroidal ruptures located temporal to the fovea running parallel. The lesions appear as pale, crescent-shaped bands, with underlying retinal pigment epithelium disruption. One of the ruptures is situated near the foveal center, though without direct involvement.

Photographer: Hector Gabriel Moreno Solano, Instituto Mexicano de Oftalmología “IMO I.A.P”

Imaging device: CLARUS

Condition/keywords: Choroidal Rupture, color fundus photograph, color wide field

Jun 25 2025 by Shivankar Sen, MS, FVRS

A 41 year old male came with complaints of Right eye blurring of vision since a day associated with watering and redness. He had no systemic illness, though gave a history of fall from bike 1 month back at the time of which he had blunt force trauma to the right side of the face. BCVA was 3/60, less than N36 in the right eye and 6/6, N6 in the left eye. Right eye had Marcus Gunn Pupil with clear lens, Left eye was within normal limits. IOP was normal; 16 in OD and 18 in OS. Retina evaluation revealed CRAO in the right eye with cilio-retinal artery sparing. Left eye was unremarkable Image Details Left to Right (Top 2 rows) Multicolor Reflectance Image (Blue-green enhanced 55 degree) revealing cilioretinal spared retinal stroma and a characteristic Cherry Red Spot; Green Reflectance showing corresopnding dark gray area with spared perfusion and black spot consistent with Cherry Red Spot on multicolor 2nd Row - 35 degree image (Multicolor Standard Reflectance and Green Reflectance) 3rd Row - SD-OCT revealing acute moderate CRAO findings with Middle retinal layer opacification and prominent middle limiting membrane (p-MLM) sign; Inner retinal layer opacification and prominent retinal pigment epithelium at the fovea with Diminished inner retinal layer stratification

Photographer: Gayathri M S

Imaging device: Heidelberg Spectralis HRA+OCT

Condition/keywords: CRAO with cilioretinal sparing, multicolor, multimodal imaging, OCT biomarkers, reflectance

Jun 13 2025 by Brandon I Fram, MD, BS

21 year-old, no past medical or family histories, with diffuse CHRPE spots suspicious for Gardner syndrome/FAP

Condition/keywords: bear tracks, CHRPE, congenital hypertrophy of the retinal pigment epithelium (CHRPE), familial adenomatous polyposis, Gardner Syndrome

Jun 4 2025 by Paulina Araujo

The 55-degree fundus photograph of the left eye shows bear tracks along the inferior temporal arcade.

Photographer: Paulina D.Araujo Martínez, Asociación para Evitar la Ceguera en México I.A.P., Hospital Dr Luis Sánchez Bulnes.

Condition/keywords: bear tracks, congenital hypertrophy of the retinal pigment epithelium (CHRPE)

May 27 2025 by César Adrián Gómez Valdivia, MD

Fundus photograph of a 21 year-old female patient with suspected Multiple Evanescent White Dot Syndrome (MEWDS). The White Dot Syndromes produce yellow-white retinal lesions classically located at the retinal pigment epithelium or outer retina and are found primarily in young adults. Symptoms of MEWDS include unilateral blurred vision, visual field loss, photopsias, and floaters.

Photographer: @eyemissu2

Imaging device: TOPCON TRC-50DX

Condition/keywords: multiple evanescent white dot syndrome (MEWDS)

Mar 26 2025 by Virginia Gebhart

54 year old female referred for iris mass. UBM shows large solid mass originating in the ciliary body and eroding into the anterior chamber under the iris epithelium. Recent CT scans revealed multiple bilateral pulmonary and hepatic nodules. Pt has been scheduled for PET scan and liver biopsy by radiation oncologist.

Photographer: Virginia Gebhart, Retina Consultants of Carolina

Imaging device: Samsung Galaxy

Condition/keywords: choroidal metastasis, ciliary body mass, metastatic cancer

Mar 25 2025 by Toolie Winters

Ultra-wide field fundus photograph of a 78-year-old woman with extensive CHRPE lesions OS. Continued observation has been recommended at this time.

Photographer: Toolie Winters

Imaging device: Optos California

Condition/keywords: CHRPE, congenital hypertrophy of the retinal pigment epithelium (CHRPE), fundus photography, Optos, Optos California, pseudocolor, ultra-wide field imaging

Mar 6 2025 by Gerardo - Montante Montelongo, MD

Fundus photograph of an 83-year-old male with a history of Diabetes, smoking, cataract surgery on the right eye in 2022, and open-angle glaucoma. Asymptomatic. Indirect ophthalmoscopy revealed 80% excavation, peripapillary atrophy, and a hyperpigmented perifoveal lesion with 35% atrophy, 10% drusen, and 5.1 mm diameter, corresponding to a CHRPE. At multimodal imaging, FFA shows hypoautofluorescence of the lesion, OCT shows preservation of internal retinal layers, atrophy of external retinal layer, with an RPE disruption, and posterior shadowing. USG shows a flat hyperechoic lesion 5.1 mm in diameter and 1.32 mm in thickness, solid and with high internal reflectance.

Photographer: Gerardo Montante-Montelongo, MD, Mexican Institute of Ophthalmology

Imaging device: Clarus 700

Condition/keywords: congenital hypertrophy of the retinal pigment epithelium (CHRPE), multimodal imaging

Jan 27 2025 by Vishal Agrawal, MD, FRCS,FACS,FASRS

16 year-old male patient presented with DOV, nyctalopia and nystagmus. Fundus revealed pigment clumping, pale disc and preserved para-arteriolar retinal pigment epithelium (PPRPE) in both eyes. Genetic testing revealed CRB1 gene mutation.

Photographer: Dr Ayushi Gupta

Imaging device: Clarus 700

Condition/keywords: retinitis pigmentosa

Jan 27 2025 by Vishal Agrawal, MD, FRCS,FACS,FASRS

16 year-old male patient presented with DOV, nyctalopia and nystagmus. Fundus revealed pigment clumping, pale disc and preserved para-arteriolar retinal pigment epithelium (PPRPE) in both eyes. Genetic testing revealed CRB1 gene mutation.

Photographer: Dr Ayushi

Imaging device: Clarus 700

Condition/keywords: retinitis pigmentosa

Jan 7 2025 by Drew Mitchell

Fundus Autofluorescence of a CHRPE and Bear Tracks.

Photographer: Drew Mitchel, OCT-C

Imaging device: Optos Silverstone

Condition/keywords: bear tracks, CHRPE, congenital hypertrophy of the retinal pigment epithelium (CHRPE)

Jan 5 2025 by César Adrián Gómez Valdivia, MD

Hamartoma of the retina and retinal pigment epithelium found in a 10 year-old male patient with type 2 neurofibromatosis history. Overlaying fibrous proliferation can be appreciated. Findings were unilateral.

Photographer: @eyemissu2

Imaging device: TOPCON TRC-50DX

Condition/keywords: hamartoma, retinal pigment epithelium (RPE) hamartoma

Oct 10 2024 by Virginia Gebhart

56 year old male with new amelanotic melanoma emanating from the ciliary body through the posterior iris epithelium. CT scan showed no evidence of metastatic disease. Pt scheduled for radioactive plaque and tumor biopsy

Photographer: Virginia Gebhart, Retina Consultants of Carolina

Imaging device: Samsung Galaxy

Condition/keywords: amelanotic melanoma, iris melanoma

Sep 6 2024 by Giriraj Vibhute

Fundus photo and autofluorescence image in a 58-year-old woman A&B: Right and left eye ultrawidefield pseudocolor imaging in case of congenital hypertrophy of RPE. C&D: Fundus autofluorescence of right and left eye of the same patient. The patient/ family members did not have any history of colon cancer. Patient was advised colonoscopy and family members were screened.

Photographer: Giriraj Vibhute, dept of retina, M M Joshi eye institute, Hubli. India

Imaging device: Optos daytona

Condition/keywords: bear tracks, congenital hypertrophy of the retinal pigment epithelium (CHRPE)

Aug 27 2024 by Monica Elena Cortizo Brown , MD

9 year old girl with pendular nystagmus, photophobia and a fundus photo that shows clear view of the choroidal vasculature due to the hypopigmentation of retinal pigment epithelium.

Photographer: Mónica Cortizo Brown , Hospital de la Luz, Ciudad de México

Condition/keywords: nystagmus, ocular albinism, oculocutaneous albinism, photophobia

Jul 25 2024 by Navneet Mehrotra, DNB

Fundus photograph of a 17 year old boy with sudden decrease in vision in his left eye. Retinal pigment epithelial changes were noticed at the macula.

Photographer: Navneet Mehrotra

Imaging device: Nidek

Condition/keywords: retinal pigment epithelium (RPE) changes

May 26 2024 by shama sharief

Funds photo with CHRPE and CHRRPE.

Condition/keywords: CHRRPE, congenital hypertrophy of the retinal pigment epithelium (CHRPE)

May 23 2024 by ARVIND JAIN M

Bilateral involving CHRRPE lesion in a 26 year old gentleman who came with complains of defective vision in both eyes since childhood. His BCVA was Right eye 5/60 and left eye 6/60. His anterior segment examination showed no abnormality with posterior segment examination showed both eyes (Fig.1a and 1b) greyish white elevated lesion involving the macula with thick fibrotic membrane causing the macular drag temporally in right eye and supero-temporally in left eye. (Fig.2a and 2b) OCT showing the thick ERM with the disorganized inner retinal layers suggestive of hamartoma of the Retina and Retinal Pigment Epithelium.

Photographer: Dr. Arvind Jain M, MBBS,MS Ophthal, FVRS

Condition/keywords: CHRRPE

May 13 2024 by Gabrielle Hallai

Electrooculogram responses on the left from a control individual with no known retinal pathology. There is a clear dark trough around 13 minutes (arrow down) and a light peak around 25 minutes (arrow up). The Arden ratio, or the light peak to dark trough ratio, is 2.54, indicative of normal retinal pigment epithelium function (normal > 1.80, abnormal < 1.65). On the right-hand side, there is a representative image from an individual with Best macular dystrophy. Note the reduced responses for both the dark and light phase. There is a reduced Arden ratio of 1.23, suggestive of abnormal retinal pigment epithelium function. An abnormal Arden ratio is universal in Best vitelliform macular dystrophy and is the most common electroretinographic change in this disease. Other bestrophinopathies such as autosomal recessive bestrophinopathy may have normal EOG. EOG testing was completed on the Diagnosys ColorDome.

Photographer: Gabrielle Hallai, PhD, Cleveland Clinic Cole Eye Institute

Imaging device: Diagnosys ColorDome

Condition/keywords: Best disease, electrooculogram, electroretinography, EOG

May 8 2024 by KANWALJEET HARJOT MADAN, M.S. (Ophthalmology); FAICO (Vitreous - Retina)

These are the fundus pics of a 28 year young male who presented with history of night blindness. Fundus examintaion revealed presence of Choroideremia. There is diffuse pigment clumping followed by atrophy of retinal pigment epithelium, photoreceptors and choriocapillaris with visible sclera and choroidal vessels in this condition. Atrophy progresses centripetally and the fovea is the last to become affected.

Photographer: Dr. Kanwaljeet Harjot Madan

Imaging device: Zeiss Clarus

Condition/keywords: choriocapillaris, choroideremia, nightblindness

Apr 24 2024 by Marcelo Zas, MD PhD

Best vitelliform macular dystrophy (BVMD) or Best disease. Is the most common autosomal dominant macular dystrophy. It involves the retinal pigment epithelium (RPE), and leads to a characteristic bilateral yellow “egg-yolk” appearance of the macula as you can see in this image. Essentially, BVMD is considered to have 6 clinical stages: Previtelliform, Vitelliform, Pseudohypopyon, Vitelleruptive, Atrophic and Choroidal neovascularization. As the disease progresses, patients may experience a slow, bilateral decrease in visual acuity, central scotoma, or metamorphopsia. With secondary CNV, visual decline can be rapid, however.

Photographer: Luciano Scorsetti MD

Condition/keywords: Macular Dystrophy

Apr 22 2024 by Angela Rico

59 year-old female with MM1 Mitochondrial Genetic Defect. V/A- OD: 20/25, OS:20/40

Photographer: Angela Rico M.D.

Condition/keywords: Dystrophy of the Retinal Pigment Epithelium

Apr 15 2024 by Virginia Gebhart

29 year old male with multiple flat CHRPE lesions, genetic testing negative for ACP genes associated with Gardner syndrome. Multiple intraretinal amelanotic lesions consistent with Benign Lobular Inner Nuclear Layer Proliferations (BLIP) of the retina

Photographer: Virginia Gebhart

Imaging device: Topcon

Condition/keywords: BLIP Benign Lobular Inner Nuclear Layer Proliferations, CHRPE, congenital hypertrophy of the retinal pigment epithelium (CHRPE)