Search results (809 results)

Jul 23 2026 by Pablo Angel García-Uribe, MD, PhD

A 61-year-old woman with a history of systemic hypertension treated with nifedipine and aspirin 100 mg daily underwent combined phacoemulsification and pars plana vitrectomy in the right eye for cataract and dense vitreous hemorrhage of initially undetermined etiology. This composite color fundus image, created from multiple photographs acquired with the ZEISS Visucam system, demonstrates extensive subretinal hemorrhage in different stages of evolution, including both chronic and recent hemorrhages. A large submacular fibrovascular scar and widespread retinal pigment epithelium alterations are also evident. The clinical appearance was highly suggestive of presumed polypoidal choroidal vasculopathy complicated by recurrent subretinal bleeding and advanced submacular fibrosis.

Photographer: David García-García, Optometrist, Clínica Oftalmológica Salauno, Mexico City

Imaging device: Fundus camera VISUCAM 524(Carl Zeiss Meditec AG, Jena, Germany)

Condition/keywords: fibrosis, idiopathic polypoidal choroidal vasculopathy, partially reabsorbed subretinal hemorrhage, reabsorbing subretinal hemorrhage, subretinal hemorrhage, subretinal blood

Jul 23 2026 by Pablo Angel García-Uribe, MD, PhD

A 61-year-old woman with a history of systemic hypertension treated with nifedipine and aspirin 100 mg daily underwent combined phacoemulsification and pars plana vitrectomy in the right eye for cataract and dense vitreous hemorrhage of initially undetermined etiology. This macula-centered color fundus photograph demonstrates a large submacular fibrovascular scar associated with extensive retinal pigment epithelium alterations and multiple areas of subretinal hemorrhage in different stages of evolution. Both chronic and more recent hemorrhagic components are visible within and surrounding the macular region. The clinical appearance was highly suggestive of presumed polypoidal choroidal vasculopathy complicated by recurrent subretinal bleeding and advanced submacular fibrosis.

Photographer: David García-García, Optometrist, Clínica Oftalmológica Salauno, Mexico City

Imaging device: Fundus camera VISUCAM 524(Carl Zeiss Meditec AG, Jena, Germany)

Condition/keywords: fibrosis, idiopathic polypoidal choroidal vasculopathy, partially reabsorbed subretinal hemorrhage, polypoidal choroidal vasculopathy (PCV), subretinal, subretinal hemorrhage, subretinal blood

Jul 22 2026 by Pablo Angel García-Uribe, MD, PhD

28 year-old patient with a history of right-eye leukocoria since the age of 15 and secondary sensory exotropia with ocular toxocariasis. Fundus autofluorescence showed an intensely hyperautofluorescent central lesion with relatively well-defined borders, corresponding to the fibroinflammatory granuloma. A heterogeneous autofluorescence pattern surrounded the lesion, with irregular marginal hypoautofluorescent areas, likely related to fibrosis, retinal pigment epithelium alterations, and a blocking effect. Mottled hyper- and hypoautofluorescent changes were also identified in the surrounding retina, consistent with chronic retinal pigment epithelium involvement. The optic disc showed homogeneous autofluorescence, and the tractional bands were associated with distortion of the posterior pole architecture.

Photographer: David García-García, Optometrist, Clínica Oftalmológica Salauno, Mexico City

Imaging device: VISUCAM 524(Carl Zeiss Meditec AG, Jena, Germany)

Condition/keywords: autofluorescence imaging, Toxocara, toxocara granuloma, toxocara scar, toxocariasis

Jul 3 2026 by Abhishek Karra, MS

Following initiation of high-dose systemic corticosteroid therapy, there was rapid anatomical recovery with complete resolution of subretinal fluid and restoration of foveal contour on OCT. Follow-up fundus photographs showed resolution of retinal elevation with residual retinal pigment epithelium alterations. This image pair highlights the dramatic structural response to prompt immunosuppressive treatment in acute VKH.

Photographer: Abhishek Karra

Imaging device: Nidek

Condition/keywords: color fundus photograph, serous retinal detachment, Vogt-Koyanagi-Harada (VKH) Symdrome

Jun 29 2026 by César Adrián Gómez Valdivia, MD

Short-wavelength fundus autofluorescence image obtained with Heidelberg Spectralis showing a central area of marked hypoautofluorescence corresponding to the macular exudative lesion and probable pigment epithelial detachment. Surrounding irregular hyperautofluorescent and hypoautofluorescent changes are seen, reflecting retinal pigment epithelium disturbance and chronic exudative activity in polypoidal choroidal vasculopathy.

Photographer: César Adrián Gómez Valdivia

Imaging device: HE

Condition/keywords: Active Polypoidal Choroidal Neovascularization, idiopathic polypoidal choroidal vasculopathy

Jun 25 2026 by César Adrián Gómez Valdivia, MD

Optical coherence tomography showing a steep dome-shaped serous pigment epithelial detachment with sharply elevated retinal pigment epithelium and associated subretinal fluid.

Photographer: César Adrián Gómez-Valdivia

Imaging device: Heidelberg

Condition/keywords: polypoidal choroidal vasculopathy (PCV)

Jun 25 2026 by César Adrián Gómez Valdivia, MD

Optical coherence tomography showing a steep dome-shaped serous pigment epithelial detachment with sharply elevated retinal pigment epithelium and associated subretinal fluid.

Photographer: César Adrián Gómez-Valdivia

Imaging device: Heidelberg

Condition/keywords: pigment epithelial detachment (PED)

Jun 22 2026 by César Adrián Gómez Valdivia, MD

Ultrawidefield green-light fundus autofluorescence image demonstrating a central area of marked hypoautofluorescence at the macula, consistent with retinal pigment epithelium atrophy, surrounded by numerous scattered flecks showing mixed autofluorescence throughout the posterior pole and extending toward the midperiphery. Findings are characteristic of Stargardt disease.

Photographer: Cesar Adrián Gómez Valdivia

Imaging device: Optos

Condition/keywords: Stargardt disease

Jun 22 2026 by César Adrián Gómez Valdivia, MD

Short-wavelength fundus autofluorescence image obtained with Heidelberg Spectralis, demonstrating a dense central area of hypoautofluorescence at the macula consistent with retinal pigment epithelium atrophy. Multiple surrounding flecks show mixed autofluorescence, forming a perifoveal/perimacular pattern characteristic of Stargardt disease.

Photographer: Cesar Adrián Gómez Valdivia

Imaging device: Hedielberg E.

Condition/keywords: autofluorescence imaging

Jun 22 2026 by César Adrián Gómez Valdivia, MD

Spectral-domain OCT obtained with Heidelberg Spectralis demonstrating central outer retinal and retinal pigment epithelium disruption with increased choroidal signal transmission, corresponding to macular atrophy. Scattered hyperreflective deposits and irregularity at the RPE/outer retinal complex are seen adjacent to the atrophic area, consistent with flecks in Stargardt disease.

Photographer: Cesar Adrián Gómez Valdivia

Imaging device: Hedelberg E.

Condition/keywords: Stargardt Disease

Jun 22 2026 by César Adrián Gómez Valdivia, MD

Color fundus photograph showing bilateral-appearing macular involvement centered at the posterior pole, with multiple yellow-white pisciform flecks and areas of retinal pigment epithelium mottling. The foveal region demonstrates pigmentary changes and atrophic-appearing alteration, consistent with Stargardt disease.

Photographer: César Adrián Gómez Valdivia

Imaging device: Topcon

Condition/keywords: Stargardt disease

Jun 22 2026 by Oftalmontt Clínica Láser

A 30 year-old female patient underwent OCT, OCTA and retinography, we can see a lesion in the optic nerve with neovascularization, a retinal hamartoma is suspected. It is a rare benign tumor, this lesion is composed of melanocytic tissue (glial and vascular). It is generally thought to be congenital and not hereditary. In the images we can see that the tumor is highly vascularized and that it extends to the foveal sector.

Photographer: Ophthalmic Medical Technologist

Imaging device: Avanti XR AngioVue OptoVue and COMPASS Centervue

Condition/keywords: Combined pigment epithelial and retinal hamartoma

Jun 19 2026 by César Adrián Gómez Valdivia, MD

Ultra-widefield fundus autofluorescence image showing extensive linear hypo- and hyperautofluorescent striae radiating from the posterior pole, corresponding to chorioretinal folds in hypotony maculopathy. FAF highlights the widespread impact of ocular hypotony on the retinal pigment epithelium and outer retinal architecture.

Photographer: César Adrián Gómez-Valdivia

Imaging device: OPTOS

Condition/keywords: maculopathy

Jun 3 2026 by Monica P Gonzalez-Collazo, MD

Wide-field fundus autofluorescence images of both eyes in a female carrier of X-linked Danon disease associated with a LAMP2 gene mutation. Images demonstrate a relatively preserved background autofluorescence pattern with scattered subtle mottled areas of increased and decreased autofluorescence. At baseline, a few small punctate hyperautofluorescent lesions are present in the peripheral retina. Over a 5-year follow-up period, these lesions become more numerous and widespread. These findings highlight progressive retinal pigment epithelium involvement in Danon disease, likely related to abnormal lipofuscin accumulation from impaired autophagic function.

Photographer: Hector Colon

Imaging device: Optos california

Condition/keywords: Danon disease, female carrier, fundus autofluorescence (FAF), hyperautofluorescence, hypoautofluorescence, inherited retinal disease, LAMP2, RPE mottling, wide-field imaging

May 5 2026 by César Adrián Gómez Valdivia, MD

CLARUS blue fundus autofluorescence image demonstrating bull’s-eye maculopathy. The posterior pole shows a well-defined parafoveal ring of abnormal autofluorescence surrounding a relatively preserved foveal center, producing the classic bull’s-eye pattern. Hypoautofluorescent areas correspond to retinal pigment epithelium atrophy or loss, while adjacent hyperautofluorescence reflects stressed or dysfunctional RPE. The macular changes are symmetric and sharply demarcated, consistent with outer retinal and RPE degeneration.

Photographer: César Adrián Gómez-Valdivia

Condition/keywords: bullseye maculopathy

May 5 2026 by César Adrián Gómez Valdivia, MD

CLARUS blue fundus autofluorescence image demonstrating bull’s-eye maculopathy. The posterior pole shows a well-defined parafoveal ring of abnormal autofluorescence surrounding a relatively preserved foveal center, producing the classic bull’s-eye pattern. Hypoautofluorescent areas correspond to retinal pigment epithelium atrophy or loss, while adjacent hyperautofluorescence reflects stressed or dysfunctional RPE. The macular changes are symmetric and sharply demarcated, consistent with outer retinal and RPE degeneration.

Photographer: César Adrián Gómez-Valdivia

Condition/keywords: bullseye maculopathy, hydroxychloroquine toxicity

May 5 2026 by César Adrián Gómez Valdivia, MD

Heidelberg fundus autofluorescence image demonstrating bull’s-eye maculopathy. The macula shows a characteristic parafoveal ring of abnormal autofluorescence surrounding the foveal center, corresponding to retinal pigment epithelium and outer retinal dysfunction. Areas of decreased autofluorescence represent RPE atrophy, while adjacent increased autofluorescence highlights stressed or metabolically altered RPE. The pattern is well demarcated and symmetric, consistent with a classic bull’s-eye configuration.

Photographer: César Adrián Gómez-Valdivia

Condition/keywords: bullseye maculopathy, hydroxychloroquine toxicity

May 5 2026 by César Adrián Gómez Valdivia, MD

Heidelberg fundus autofluorescence image demonstrating bull’s-eye maculopathy. The macula shows a characteristic parafoveal ring of abnormal autofluorescence surrounding the foveal center, corresponding to retinal pigment epithelium and outer retinal dysfunction. Areas of decreased autofluorescence represent RPE atrophy, while adjacent increased autofluorescence highlights stressed or metabolically altered RPE. The pattern is well demarcated and symmetric, consistent with a classic bull’s-eye configuration.

Photographer: César Adrián Gómez-Valdivia

Condition/keywords: bulls eye maculopathy, hydroxychloroquine toxicity

May 5 2026 by César Adrián Gómez Valdivia, MD

50-degree color fundus photographs demonstrating classic bull’s-eye maculopathy. The posterior pole shows a well-demarcated parafoveal ring of retinal pigment epithelium mottling/atrophy surrounding a relatively preserved central foveal area, creating the characteristic bull’s-eye appearance. The macular changes are bilateral and symmetric, with perifoveal pigmentary alteration and outer retinal/RPE degeneration. No obvious hemorrhage, exudation, or signs of active choroidal neovascularization are observed in these images.

Photographer: César Adrián Gómez-Valdivia

Condition/keywords: bull's eye maculopathy, hydroxychloroquine toxicity

May 5 2026 by César Adrián Gómez Valdivia, MD

50-degree color fundus photographs demonstrating classic bull’s-eye maculopathy. The posterior pole shows a well-demarcated parafoveal ring of retinal pigment epithelium mottling/atrophy surrounding a relatively preserved central foveal area, creating the characteristic bull’s-eye appearance. The macular changes are bilateral and symmetric, with perifoveal pigmentary alteration and outer retinal/RPE degeneration. No obvious hemorrhage, exudation, or signs of active choroidal neovascularization are observed in these images.

Photographer: César Adrián Gómez-Valdivia

Condition/keywords: bullseye maculopathy, hydroxychloroquine toxicity

May 4 2026 by César Adrián Gómez Valdivia, MD

Macular OCT B-scan demonstrating a choroidal osteoma involving the macular region. The scan shows an elevated, hyperreflective choroidal lesion with associated retinal pigment epithelium and outer retinal layer disruption. Mild intraretinal and subretinal fluid are present, suggesting associated exudative activity. Findings are consistent with choroidal osteoma.

Photographer: César Adrián Gómez-Valdivia

Imaging device: Heidelberg E.

Condition/keywords: macular choroidal osteoma

Apr 27 2026 by Sherrie Cox

56 year-old female with CHRPE. It is long standing flat benign pigmented spot. Will monitor ongoing, no treatment necessary.

Photographer: Jaylynn Frost, Testing Technician, Florida Eye Surgeons and Associates

Condition/keywords: CHRPE

Jan 28 2026 by KANWALJEET HARJOT MADAN, M.S. (Ophthalmology); FAICO (Vitreous - Retina)

This is the fundus image of LE of a 16 year-old male depicting presence of Retinal Astrocytic Hamartoma in peripapillary region. Few depigmented areas of retinal pigment epithelium can be seen infero-temporally. He had associated Tuberous Sclerosis. Retinal Astrocytoma is a benign glial cell tumor, often asymptomatic tumor affecting 40-50% of patients with Tuberous Sclerosis Complex (TSC).

Photographer: Dr. Kanwaljeet Harjot Madan, Thind Eye Hospital, Jalandhar City (Punjab) INDIA.

Imaging device: Zeiss Fundus Camera

Condition/keywords: astrocytoma, tuberous sclerosis

Dec 22 2025 by Kimberly Wakester, COA, OCT-C

Optomap RGB image of an 48-year-old man with a CHRPE with lacunae in the right eye. Recommended yearly observation.

Photographer: Kimberly Wakester, COA, OCT-C

Imaging device: Optos California

Condition/keywords: congenital hypertrophy of the retinal pigment epithelium (CHRPE)

Dec 17 2025 by SHRADDHA RAJ SHRIVASTAVA

Right eye pseudocolor fundus photo of a 50 year old patient, known case of bilateral familial dominant drusens with right eye CNVM, having undergone multiple intravitreal anti-VEGF injections. Image shows a CDR of 0.3:1, with numerous drusens at macula with residual lipid exudation from CNVM, along the infero-temporal arcade. Temporal to the fovea, we can see a vertical hyperpigmented line corresponding to retracted and redundant torn Retinal pigment epithelium, leaving behind a well circumscribed area of depigmented fundus with bare Bruch's membrane underlying the retina, findings suggestive of an RPE tear post multiple intravitreal injections.

Photographer: Dr. Shraddha Raj Shrivastava

Imaging device: Nidek Mirante SLO/OCT (Confocal scanning/Spectral domain OCT)

Condition/keywords: choroidal neovascular membrane (CNVM), Doyne's Honeycomb, FAMILIAL DOMINANT DRUSEN, lipid exudation, retinal pigment epithelium, RPE Rip