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By Marcelo Zas, MD PhD
Hospital de Clinicas-University of Buenos Aires
Co-author(s): Luciano Scorsetti MD, Pablo Chiaradia MD PhD, Juan Cortalezzi MD, Alejandro Tau MD, Marcos Mendaro MD, Mariano Cotic MD, Virginia Vittar MD, Natalia Gerschovsky MD, Enzo Dilascio MD - Uploaded on Apr 24, 2024.
- Last modified by Joshua Friedman on Apr 24, 2024.
- Rating
- Appears in
- Miscellaneous
- Condition/keywords
- Macular Dystrophy
- Photographer
- Luciano Scorsetti MD
- Description
- Best vitelliform macular dystrophy (BVMD) or Best disease. Is the most common autosomal dominant macular dystrophy. It involves the retinal pigment epithelium (RPE), and leads to a characteristic bilateral yellow “egg-yolk” appearance of the macula as you can see in this image. Essentially, BVMD is considered to have 6 clinical stages: Previtelliform, Vitelliform, Pseudohypopyon, Vitelleruptive, Atrophic and Choroidal neovascularization. As the disease progresses, patients may experience a slow, bilateral decrease in visual acuity, central scotoma, or metamorphopsia. With secondary CNV, visual decline can be rapid, however.