Search results (54 results)
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Susac's Syndrome
Feb 13 2018 by John S. King, MD
Background: 46-year-old WF with CML (stable on Sprycel) saw her PCP for headaches without known cause; Headaches worsened and became confused, disoriented, off balance, and impaired short term memory. Heme-oncology ordered MRI that showed abnormal signal in the cerebellum and other parts of the brain, and LP has elevated protein. LP did show positive tau test, but fortunately, was a false positive for CJD. IV and PO steroids started and symptoms improved. MRI showed much improvement one month since starting steroids. 3 weeks later had a scotoma in right eye and eye doctor did not find anything at that time to cause it. Tinnitus developed (and some intermittent vertigo before that) and ENT referred back to eye doctor, who then referred the patient to Dr. Zocchi. He found a CWS and BRAO OD, and bilateral arteritis. She had some additional work-up for vasculitis. Given the retinal arteritis, cochlear issues, and MRI findings, Dr.Zocchi suspected Susac's Syndrome. She was started on multiple regimens including prednisone, IVIG, azathiprine, and MTX, and has had the best reponse to IVIG (FA shows a recurrence/worsening while adjusting IMT). She is stable and doing well with 20/20 vision in both eyes.
Photographer: Kay Dalby
Imaging device: Topcon
Condition/keywords: retinal vasculitis, Susac's syndrome
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AMD with Subretinal Hemorrhage Recurrence OS
Aug 24 2012 by John S. King, MD
Six months after subretinal tPA and regular antiVEGF, last of which was Eylea, there was a recurrent hemorrhage, and acuity drop from 20/50 to HM; discussed repeat subretinal tPA.
Photographer: Kristin Konecki, OcuSight Eye Care Center, Rochester, NY
Condition/keywords: EYLEA, subretinal hemorrhage
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Sympathetic Ophthalmia
Sep 28 2012 by Joseph M. Civantos, MD
Recurrence of S.O. when steroids were tapered after 4 months. Vision has dropped to 20/60.
Condition/keywords: sympathetic ophthalmia
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choroidal lymphoma
Nov 25 2012 by Mallika Goyal, MD
Left eye of a 60-year-old lady shows multiple sub-retinal yellowish masses of choroidal lymphoma. Radiotherapy resulted in complete regression with recurrence after 10 months.
Photographer: Mallika Goyal, MD, Apollo Health City, Hyderabad, India
Condition/keywords: lymphoma
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Acute Posterior Multifocal Placoid Pigment Epitheliopathy
Jan 4 2019 by Cláudia Farinha
Composite image of both eyes of a 27-year-old male with APMPPE. In the fundus photograph, multiple yellowish placoid lesions are observed in the posterior pole in both eyes. The ICGA revealed more lesions than those observed in fundoscopy, and these were hypofluorescent through the angiogram as expected. The en face OCTA segmented at the level of the choriocapillaris revealed areas of ischemia in close correspondence with the hypofluorescent lesions (image superimposed in ICGA ). The OCT b-scan with superimposed flow shows disruption and hyperreflectivity of the external retinal layers in the affected areas and again the absence of flow in the choriocapillaris underneath. A systemic study was carried out to exclude other inflammatory and infectious causes of placoid retinochoroidopathy. The clinical picture resolved after approximately one month from the onset, without recurrence.
Photographer: Pedro Melo, Ophthalmology Department, Centro Hospitalar e Universitário de Coimbra, Coimbra Portugal
Condition/keywords: acute posterior multifocal placoid pigment epitheliopathy (APMPPE), white dot syndrome
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AMD and Subretinal Heme Recurrence
Aug 24 2012 by John S. King, MD
Recurrent SRH 6m s/p subretinal tPA and regular anti-VEGF.
Photographer: Kristin Konecki, OcuSight Eye Care Center, Rochester, NY
Condition/keywords: subretinal hemorrhage
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Choroidal Lymphoma
Nov 25 2012 by Mallika Goyal, MD
Left eye of a 60-year-old lady shows multiple sub-retinal yellowish masses. This is a recurrence 10 months following complete resolution of the lesions post-radiotherapy. Radiotherapy was repeated with regression of tumor.
Photographer: Mallika Goyal, MD, Apollo Health City, Hyderabad, India
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Choroidal Hemangioma: OCT One Month (L) and Two Months (R) Since PDT
Nov 17 2019 by John S. King, MD
67-year-old white male with 6 days of decreased vision and known history of choroidal hemangioma, who had received PDT years ago for symptomatic SRF, had recurrence of SRF. PDT was applied to the lesion and one month later there is less subfoveal SRF, and vision has increased to 20/50 from 20/150. One month later the OCT shows that SRF continues to decrease and vision has improved to 20/40.
Condition/keywords: choroidal hemangioma
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Choroidal Lymphoma
Nov 25 2012 by Mallika Goyal, MD
Right eye of a 60-year-old lady shows multiple sub-retinal yellowish masses. This is a recurrence 10 months following complete resolution of the lesions post-radiotherapy. Radiotherapy was repeated with regression of tumor.
Photographer: Mallika Goyal, MD, Apollo Health City, Hydeabad, India
Condition/keywords: lymphoma
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Choroidal Lymphoma
Nov 25 2012 by Mallika Goyal, MD
Right eye of a 60-year-old lady shows multiple sub-retinal yellowish masses. This is a recurrence 10 months following complete resolution of the lesions post-radiotherapy. Radiotherapy was repeated with regression of tumor.
Photographer: Mallika Goyal, MD, Apollo Health City, Hydeabad, India
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choroidal lymphoma
Nov 25 2012 by Mallika Goyal, MD
Left eye of a 60-year-old lady shows multiple sub-retinal yellowish masses of choroidal lymphoma. Radiotherapy resulted in complete regression with recurrence after 10 months.
Photographer: Mallika Goyal, MD, Apollo Health City, Hyderabad, India
Condition/keywords: lymphoma
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choroidal lymphoma
Nov 25 2012 by Mallika Goyal, MD
Left eye of a 60-year-old lady shows multiple sub-retinal yellowish masses of choroidal lymphoma. Radiotherapy resulted in complete regression with recurrence after 10 months.
Photographer: Mallika Goyal, MD, Apollo Health City, Hyderabad, India
Condition/keywords: lymphoma
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Choroidal Metastasis
Apr 22 2016 by Mallika Goyal, MD
Left fundus of a 65-year-old male physician, ex-smoker, shows a choroidal metastasis superior to macula from primary lung carcinoma non-responsive to chemotherapy. Resolved with radiotherapy with recurrence at same site after 2 months.
Photographer: Mallika Goyal, MD, Apollo Health City, Hyderabad, India
Condition/keywords: choroidal metastasis
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Choroidal Metastasis
Apr 22 2016 by Mallika Goyal, MD
Right fundus of a 65-year-old male physician, ex-smoker, shows a choroidal metastasis nasal to disc from primary lung carcinoma non-responsive to chemotherapy. Resolved with radiotherapy with recurrence at same site after 2 months.
Photographer: Mallika Goyal, MD, Apollo Health City, Hyderabad, India
Condition/keywords: choroidal metastasis
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Choroidal Metastasis
Apr 22 2016 by Mallika Goyal, MD
Left fundus of a 65-year-old male physician, ex-smoker, shows a recurrent choroidal metastasis superior to macula from primary lung carcinoma non-responsive to chemotherapy. The lesion had initially resolved with radiotherapy with recurrence at same site after 2 months.
Photographer: Mallika Goyal, MD, Apollo Health City, Hyderabad, India
Condition/keywords: choroidal metastasis
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Choroidal Metastasis
Apr 22 2016 by Mallika Goyal, MD
Left fundus of a 65-year-old male physician, ex-smoker, shows a recurrent choroidal metastasis superior to macula from primary lung carcinoma non-responsive to chemotherapy. The lesion had initially resolved with radiotherapy with recurrence at same site after 2 months.
Photographer: Mallika Goyal, MD, Apollo Health City, Hyderabad, India
Condition/keywords: choroidal metastasis
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Choroidal Metastasis
Apr 22 2016 by Mallika Goyal, MD
Left fundus of a 65-year-old male physician, ex-smoker, shows a recurrent choroidal metastasis superior to macula from primary lung carcinoma non-responsive to chemotherapy. The lesion had initially resolved with radiotherapy with recurrence at same site after 2 months.
Photographer: Mallika Goyal, MD, Apollo Health City, Hyderabad, India
Condition/keywords: choroidal metastasis
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Circumscribed Choroidal Hemangioma
Oct 12 2019 by John S. King, MD
67-year-old white male with 6 days of decreased vision and known history of choroidal hemangioma, who had received PDT years ago for symptomatic SRF, had recurrence of SRF. PDT was applied to the lesion and one month later there is less subfoveal SRF, and vision has increased to 20/50 from 20/150. Will follow up in a month. Pictured is an orange-red choroidal mass with margins that blend with the surrounding choroid.
Photographer: Shelly Blair
Condition/keywords: choroidal hemangioma, photodynamic therapy
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Dry Macular Scar With Recurrence
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Eccentric Macular Scar With Recurrence
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Fingolimob Associated Macular Edema (FAME)?
Jun 1 2019 by John S. King, MD
60 year old caucasian female with two week history of decreased vision in the left eye. Background history includes multiple sclerosis for which she uses Gileyna for the past five years, and no history of uveitis or recent MS relapse. Her vision in the left eye was 20/100 J5. The eye appeared overall "quiet" with the exception of rare cells in the anterior vitreous. The fundus appearance and FA can be seen in the images provided. OCT shows CME and SRF in OS only (left image). STK was administered and neurologist was able to discontinue the Gileyna. STK has been reported to be effective in FAME in patients who continue Gileyna (see below). 10 days later the CME had decreased significantly. 8 weeks later the edema had resolved as seen in the OCT images of the initial and latest appearance. Of note, this is a late presentation for FAME, and there was some rare debris in the anterior vitreous; it is possible, although no history of uveitis and the MS was inactive, that the CME may be related to other causes like uveitis (if there is recurrence of CME while patient is off Gileyna, then further work-up will be performed) Minuk A, Belliveau MJ, Almeida DR, Dorrepaal SJ, Gale JS. Fingolimod-associated macular edema: resolution by sub-tenon injection of triamcinolone with continued fingolimod use. JAMA ophthalmol 2013; 131(6): 802–804.
Photographer: Kay Dalby
Imaging device: Cirrus
Condition/keywords: cystoid macular edema (CME), Gilenya, macular edema
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Juxtafoveal Hemorrhage with Recurrence
Oct 8 2012 by Jeffrey G. Gross, MD, FASRS
Juxtafoveal hemorrhage with recurrence.
Condition/keywords: juxtafoveal hemorrhage, recurrence
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Ocular Histoplasmosis Syndrome (OHS)
Oct 8 2013 by Maurice F. Rabb
Thirty six year old white male stated that approximately 5 years earlier he had a blurry spot in his left eye that went away spontaneously after 3 months. Three years later the spot returned. He was seen by a local ophthalmologist who noted two "histo spots" in the left eye. Over the next 6 months his vision deteriorated from 20/30 to 20/200 in the left eye. A week prior to being seen at the UIHC he noted bulginess in his right eye. Visual acuity without correction was 20/15 OD, 20/200 OS. Color fundus photography and fluorescein angiography were performed and the patient was treated with argon laser photocoagulation. Vision decreased to 20/30 following laser surgery, but within two weeks returned to 20/15 and remained that way over the next two years. OVer the following 15 years the patient did well although he developed a recurrence in the untreated left eye and periodically he experienced vague changes in his central field.
Condition/keywords: ocular histoplasmosis syndrome (OHS)
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Ocular Histoplasmosis Syndrome (OHS)
Oct 8 2013 by Maurice F. Rabb
Thirty six year old white male stated that approximately 5 years earlier he had a blurry spot in his left eye that went away spontaneously after 3 months. Three years later the spot returned. He was seen by a local ophthalmologist who noted two "histo spots" in the left eye. Over the next 6 months his vision deteriorated from 20/30 to 20/200 in the left eye. A week prior to being seen at the UIHC he noted bulginess in his right eye. Visual acuity without correction was 20/15 OD, 20/200 OS. Color fundus photography and fluorescein angiography were performed and the patient was treated with argon laser photocoagulation. Vision decreased to 20/30 following laser surgery, but within two weeks returned to 20/15 and remained that way over the next two years. OVer the following 15 years the patient did well although he developed a recurrence in the untreated left eye and periodically he experienced vague changes in his central field.
Condition/keywords: ocular histoplasmosis syndrome (OHS)
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Ocular Toxoplasmosis
May 26 2016 by Sam Kanavati
A blue autofluorescence image of an inactive well-demarcated chorioretinal scar involving the right optic nerve head secondary to ocular toxoplasmosis in a 65 year-old female patient. This scar dates back to 1971 without any recurrence. Although the scar is extensive, visual acuity was 6/6 but with a corresponding visual field defect.
Photographer: Sam Kanavati, University Hospital Southampton NHS Foundation Trust, UK
Imaging device: Heidelberg Spectralis
Condition/keywords: inactive toxoplasmosis