Search results (431 results)

  • Inflammatory pupillary membrane in patient with endophthalmitis

    Jan 28 2023 by Kingston Rodolfo Ureña-Wong, MD, Opht, MSc

    Anterior segment photography of a 54-year-old woman with post phacoemulsification endophthalmitis. She did not improve after first intravitreal antibiotics injection and develop an inflammatory pupillary membrane. After two vitrectomies, and a complete three intravitreal injections scheme, we decided to remove the intraocular lens and capsules.

    Photographer: Marco Antonio Rubio-Atonal,UNAM, Asociación para evitar la ceguera en México

    Imaging device: Zeiss Clarus 700

    Condition/keywords: endophthalmitis, pupillary membranes

  • CMV Retinitis with Frosted Branch Angiitis

    Sep 23 2020 by Nimesh A. Patel, MD, FASRS

    Fundus photo showing peri-vascular inflammation of both arteries and veins with translucent exudation (yellow arrow). Superior nasally, there is classic retinal whitening with retinal hemorrhages superior. This patient was found to have a low CD4 count and a diagnosis of AIDS was made.

    Condition/keywords: cytomegalovirus (CMV), HIV, uveitis

  • Choroidal Granuloma

    Apr 7 2017 by Manish Nagpal, MD, FRCS (UK), FASRS

    Colour photo of a case of peripapillary choroidal granuloma presenting with exudation and hemorrhages.

    Photographer: pooja barot

    Condition/keywords: choroid, granuloma, inflammation

  • Chorioretinitis with Overlying Vitreous Stranding/Vitritis

    Mar 23 2023 by Isaac Agranoff

    Fundus photograph of a 37-year-old woman presenting with chorioretinitis with overlying vitreous stranding/vitritis that has remained unchanged for multiple years. Patient presented with irritation and blurred vision and her vision was 20/40 OD. The OCT revealed evidence of low-grade inflammation and the recommend treatment was anti-inflammatory eye drops at this time and to obtain second opinion with another physician in the office.

    Photographer: Isaac Agranoff, Technician

    Imaging device: Optos California

    Condition/keywords: chorioretinal scar, chorioretinitis, inflammation, Optos, ultra-wide field imaging, vitritis

  • Choroidal Granuloma

    Apr 7 2017 by Manish Nagpal, MD, FRCS (UK), FASRS

    Fluorescein angiography of a case of peripapillary choroidal granuloma presenting with exudation and hemorrhages.

    Photographer: Pooja Barot

    Condition/keywords: choroid, granuloma, inflammation

  • Foveoschisis secondary to high myopia

    Mar 13 2015 by Niloofar Piri, MD

    Infrared and HD-OCT of the right eye in a 55-year-old African American female with high myopia (more than -6.00 D), BCVA: 20/25 OU Cartwheel appearance of the fovea in the infrared imaging is visible. HD- OCT demonstartes schisis in different layers of the retina (both NFL and OPL; notice stretching of the Muller cells); VMT is also present . Outer retinal layers are preserved which explains the good vision . She had the same findings in OS.

    Photographer: Niloofar Piri, MD

    Imaging device: Heidelberg Spectralis

    Condition/keywords: high myopia, retinoschisis

  • Myelinated Nerve Fibre (MNF)

    Jun 17 2023 by Harsh Vardhan Singh, MS

    Fundus photograph of 32-year-old male having good best corrected visual acuity in both eyes with right eye having high myopia & MNF as incidental finding

    Photographer: Dr Harsh Vardhan Singh, Assistant Professor, AIIMS, Guwahati

    Condition/keywords: medullated nerve fibers, MNF, myelinated nerve fiber layer, myelinated nerve fibers, Nerve fiber layer arrangements, NFL

  • Retinocoroiditis Inactiva Por Toxoplasmosis

    Apr 28 2025 by Paulina Araujo

    Fundus photography demonstrates a 2-disc-diameter chorioretinal scar in the superior temporal arcade, consistent with inactive toxoplasmic retinochoroiditis. The lesion exhibits pigmented borders and central atrophy, with adjacent splinter hemorrhages and vascular sheathing. No vitreous inflammation or active satellite lesions are present.

    Photographer: Paulina D.Araujo Martínez, Asociación para Evitar la Ceguera en México I.A.P., Hospital Dr Luis Sánchez Bulnes.

    Condition/keywords: toxoplasmosis chorioretinitis

  • Acute myeloid leukemia

    Dec 9 2012 by Mallika Goyal, MD

    Right eye of a 21-year-old gentleman with acute myeloid leukemia who is undergoing chemotherapy and has low platelet counts (17,000) shows multiple pre-retinal haemorrhages. Other eye has similar picture. There is no vascular occlusion or inflammation. Visual prognosis remains good with spontaneous resolution expected over few weeks.

    Photographer: Mallika Goyal, MD, Apollo Health City, Hyderabad, India

    Condition/keywords: preretinal hemorrhage

  • Advanced Proliferative Diabetic Retinopathy With Fibrovascular Proliferation

    Jan 4 2019 by Isha Agarwalla

    A 29-year-old female with a long-standing history of diabetes mellitus presented with a fibrovascular membrane (FVM) at the viteroretinal interface due to underlying inflammation and angiogenesis induced by ischemia. FVM involved the disc and extended towards the superior and inferior arcades along with extensive capillary drop out areas due to micro aneurysms.

    Condition/keywords: fibrovascular proliferation, proliferative diabetic retinopathy (PDR)

  • Auto-Enucleation with Tire Iron

    Oct 19 2012 by Larry Halperin, MD

    Auto-enucleation with tire iron

    Condition/keywords: enucleation, self-inflicted, trauma

  • Choroidopathy

    May 27 2020 by Jamin S. Brown, MD

    Fluorescein angiography image of 28 year old female with focal chorioretinal inflammation, macular or paramacular OS. chorioretinal scar OS.

    Photographer: Jeffrey Barker, Retina-Vitreous Surgeons of CNY

    Condition/keywords: choroidopathy

  • CRVO

    Nov 26 2020 by Priya Rasipuram Chandrasekaran, MBBS, DO, DNB, FRCS

    A 44-year-old male patient presented with no underlying systemic illness presented with this picture showing extensive scattered superficial and deep retinal haemorrhages to confluent retinal hemorrhages extending to all the quadrants associated with marked dilatation and tortuosity of vessels and associated with optic disc edema, macular edema and retinal thickening giving the appearance of blood and thunder retina.

    Condition/keywords: central retinal vein occlusion (CRVO)

  • Extensive Chorioretinal Scarring With Partial Macular Sparing

    Apr 22 2025 by Maxwell J Wingelaar, MD

    Fundus autofluorescence of extensive chorioretinal scarring in the left eye.

    Photographer: Killian Roberts

    Imaging device: Heidelberg Spectralis AF

    Condition/keywords: chorioretinal atrophy, chorioretinal inflammations

  • Giant Papillary Conjunctivitis, Left Upper Eyelid

    Jul 22 2013 by Jason S. Calhoun

    Contact lens wearer, in for exam. Has rough feeling underneath both eyelids. Patient thought it was through SCL wear. Patient VA was 20/20. right eye, 20/30, left eye. Underneath the left upper eyelid, you can see papillary inflammation and redness.

    Photographer: Jason S. Calhoun, Department of Ophthalmology, Mayo Clinic Jacksonville, Florida

    Imaging device: TOPCON D-90 SL NIKON CAMERA

    Condition/keywords: giant papillary conjunctivitis

  • Granulomatous Uveitis

    May 18 2020 by McGill University Health Centre

    Granulomatous uveitis is found in many inflammatory diseases, and is generally characterized by a predominant histiocytic infiltrate forming a “wall” (granuloma) around a pathogen or foreign body. This is an example of granulomatous uveitis. The eye is aphakic; the uveal track is thickened; and a granuloma is present and attached to the endothelium of the cornea (arrow). The anterior chamber is filled with a hazy material (arrowhead). The vitreous is fibrotic and tractional bands are also present (*).

    Condition/keywords: granulomatous uveitis

  • Idiopathic Peripapillary CNV

    Jan 4 2024 by Virginia Gebhart

    13 year old female with inactive CNV. Increased pigment 360 at 1 year follow up. No inflammation or SRF, pt remains asymptomatic

    Photographer: Virginia Gebhart

    Imaging device: Optos California

    Condition/keywords: choroidal neovascularization (CNV), peripapillary choroidal neovascularization (PPCNVM)

  • Mild Patton's Lines in IIH - Initial Photos

    Jan 16 2019 by John S. King, MD

    18-year-old African American female with increased BMI with a history of headaches, nausea, transient diplopia and vision loss that she notices when getting up from her bed (and goes away after standing upright) for the last two weeks. Went to PCP and was treated for the flu, and after no improvement and visual symptoms known, was sent to ED. MRI did not show any masses and showed empty sella turcia. Vision 20/30 OD and 20/20 OS; no RAPD; IOP 15OU; no anterior segment or vitreous inflammation; discs are elevated with obscuration of the disc margins and some of the smaller vessels; there are no SVPs; there are mild Patton's lines temporally (see Initial Photos). The optic disc cube shows 360 degrees of RNFL thickening (see OCT). Was referred to near-ophthalmologist, Dr. Doyle. She obtained additional work-up, and LP opening pressure was high, and MRV showed bilateral transverse sinus stenosis. Patient showed steady improvement with medical therapy, that included weight loss and oral diamox. On her last visit with Dr. Doyle, vision has remained stable at 20/20-20/25 without an enlarged blindspot; there are SVPs and optic disc edema has resolved (see Post Treatment Photos); she is currently on 1000 mg of diamox and has lost 15 pounds, and no stinting procedure needed.

    Photographer: Gretchen Harper

    Imaging device: Topcon 50

    Condition/keywords: idiopathic intracranial hypertension, optic disc edema, papilledema, Patton's Lines

  • Multiple Areas of Myelinated RNFL OD

    Sep 18 2019 by John S. King, MD

    68-year-old African American male presented with an acute PVD in the fellow eye. Fellow eye had similar findings, but the pics were not as good as OD.

    Photographer: Brittany Dewberry

    Imaging device: Optos CA

    Condition/keywords: myelinated nerve fiber layer, myelinated nerve fibers

  • Myelinated Nerve Fibers

    Apr 18 2025 by DR Rohit Gupta

    The **myelinated nerve fibers of the optic disc** (also known as **medullated nerve fibers**) are retinal nerve fibers that retain their myelin sheath as they pass through the optic nerve head. Normally, retinal nerve fibers are unmyelinated to allow for light transparency, but in some cases, myelination extends anteriorly into the retina, appearing as a striking white, feathery patch on the optic disc or peripapillary retina. ### **Key Features:** 1. **Appearance:** - Dense, white, striated patches with feathery edges. - Typically located at the superior or inferior pole of the optic disc. - May obscure retinal vessels underneath. 2. **Clinical Significance:** - Usually **benign** and asymptomatic. - **Congenital** (present at birth or early childhood). - Rarely associated with **visual field defects** (e.g., scotomas corresponding to the area of myelination). - Occasionally linked with **high myopia** or **amblyopia** if extensive. 3. **Pathophysiology:** - Failure of oligodendrocytes or Schwann cells to stop myelination at the lamina cribrosa. - Normally, myelination stops at the optic nerve head, but in this condition, it extends into the retina. 4. **Diagnosis:** - **Fundoscopy:** Classic white, feathery appearance. - **Optical Coherence Tomography (OCT):** Shows thickened retinal nerve fiber layer (RNFL). - **Visual Field Testing:** May detect defects if large. 5. **Differential Diagnosis:** - Optic disc edema - Cotton wool spots - Retinoblastoma (rarely, but must be ruled out in children) 6. **Management:** - No treatment required if asymptomatic. - Monitor for amblyopia in children. - Rare cases with significant visual impairment may need further evaluation. ### **Fun Fact:** Myelinated nerve fibers are seen in **~0.5-1%** of the population and are usually an incidental finding.

    Photographer: Dr Rohit gupta

    Imaging device: Samsung S21

    Condition/keywords: Medulated Nerve fibre, Medullated Nerve fibres, myelinated nerve fibers, Myelinated Nerve Fibres, optic disc drusen

  • Posterior Placoid Chorioretinopathy

    Dec 19 2020 by John S. King, MD

    44-year-old white female seen over the weekend complaining of a "spot" in her vision centrally OD for three days. She was referred over by another eye doctor who was concerned about a possible retinal detachment vs ARN in that eye. Her past medical history includes adrenal insufficiency for which she takes a low dose of hydrocortisone, thyroxine (post thyroidectomy), Plaquenil (inflammatory arthritis). She is divorced with one partner and denies any IVDU. Va 20/200 OD and 20/20 OS, IOP 12 OU, pupils mydriatic post gtts (light desaturation OD). There was 1+ A/C cell OD, O/W unremarkable anterior segment OU; in the posterior segment OD there was 1+ vitritis with a diffusely swollen optic disc and a large yellowish placoid lesion in the macula with yellowish border and extended out past the arcades inferiorly, as well as another lesion smaller in the IN periphery, and two possible smaller spots SN (See Photo above). There was a trace vitreous cell OS with a large, granular placoid lesion nasally. The OCT showed mild subfoveal fluid with nodular areas in the RPE and some overlying irregular architecture of the outer retina. Syphilis was a concern at this point. She denied any hand or foot rash, and said that she was recently working on the house, and her hands were dried out. There did appear to be a rash on the hand, and later learned that she had a rash on the soles of her feet. She was sent to ED for a work-up and her syphilis IgG was positive and VDRL 1:128, and negative for HIV. She was started on a course IV Penicillin (40mg PO steroid two days after tx started). She has responded well. A few days after treatment her visual acuity has improved to 20/60 OD; there was no anterior segment inflammation OU, and decreased vitreous cell OU. Disc edema was improved. The large placoid lesion in the macula of the right eye was slightly enlarged, but more granular in appearance without a distinct yellowish border, and the smaller lesions SN had dissipated. OCT showed resolution of the subfoveal fluid and an improved appearance of the outer retina and RPE layer.

    Imaging device: Optos CA

    Condition/keywords: acute syphilitic posterior placoid chorioretinitis, syphilis

  • Choroidal Granuloma Secondary to Tuberculosis

    Mar 14 2013 by Eduardo Torres-Porras, MD

    OCT scan through the granuloma shows attachment of the retinal pigment epithelial-choriocapillaris layer and the neurosensory retina over the granuloma (“contact” sign), inflammatory retinal infiltrate in the deeper retinal layers and subretinal fluid.

    Photographer: Eduardo Torres Porras

    Imaging device: Cirrus

    Condition/keywords: optical coherence tomography (OCT), tubercular choroidal granuloma

  • Extensive Chorioretinal Scarring with Partial Macular Sparring

    Apr 22 2025 by Maxwell J Wingelaar, MD

    A multicolor photo showing chorioretinal scarring with partial macular sparing in the left eye.

    Photographer: Killian Roberts

    Imaging device: Heidelberg Spectralis Multicolor Photo

    Condition/keywords: chorioretinal atrophy, chorioretinal inflammations

  • Giant Papillary Conjunctivitis, Left Upper Eyelid

    Jul 22 2013 by Jason S. Calhoun

    Contact lens wearer in for exam. Has rough feeling underneath both eyelids. Patient thought it was through SCL wear. Patient VA was 20/20. right eye, 20/30, left eye. Underneath the left upper eyelid, you can see papillary inflammation and redness.

    Photographer: Jason S. Calhoun, Department of Ophthalmology, Mayo Clinic Jacksonville, Florida

    Imaging device: TOPCON D-90 SL NIKON CAMERA

    Condition/keywords: giant papillary conjunctivitis

  • "Starry Sky" Fundus in Vogt-Koyanaki-Harada Syndrome

    Jan 10 2018 by Peter H. Tang, MD, PhD

    Fluorescein angiography imaging of a 27-year-old male with acute inflammation as part of Vogt-Koyanagi-Harada Syndrome.

    Imaging device: Optos California

    Condition/keywords: chorioretinal inflammations, retina, uveitis, Vogt-Koyanagi-Harada