Lancaster Course in Ophthalmology » Unit 05 Diseases of the Eyelids

Feb 20 2019 by Lancaster Course in Ophthalmology

Normal lid skin from a darkly pigmented individual.

Condition/keywords: normal eye

Feb 20 2019 by Lancaster Course in Ophthalmology

The thickened epidermis shows acanthosis (prickle cell proliferation) and parakeratosis (retention of nuclei in desquamating surface-layer cells).

Condition/keywords: acanthosis, epidermis, Keratosis pilaris (KP), prickle cell proliferation

Feb 20 2019 by Lancaster Course in Ophthalmology

Loss of orderly maturation of epidermal cells (dysplasia). The red blood cell-like ellipse in the center of the epithelium is a cell which has keratinized out of place (dyskeratosis).

Condition/keywords: dyskeratosis, dysplasia, epidermal cells, epithelium

Feb 20 2019 by Lancaster Course in Ophthalmology

Marked downward proliferation of acanthotic epithelium (pseudoepithe­liomatous hyperplasia) at the edge of a fungal ulcer.

Condition/keywords: acanthosis, fungal ulcer

Feb 20 2019 by Lancaster Course in Ophthalmology

Thick layer of basophilic (bluish) glassy fibers in the subepithelial tissue represents elastosis.

Condition/keywords: basophilic, elastosis, subepithelial tissue

Feb 20 2019 by Lancaster Course in Ophthalmology

Papula lid lesions of sarcoid. (Courtesy of Donald Morris, M.D.)

Condition/keywords: eye lid, sarcoid

Feb 20 2019 by Lancaster Course in Ophthalmology

Discrete pink clumps of epithelioid cells in sarcoid. Note the giant cell in one clump.

Condition/keywords: epithelioid cells, giant cell, sarcoid

Feb 20 2019 by Lancaster Course in Ophthalmology

Small chalazion in situ in the lid. Lipogranulomatous reaction around large and small clear spaces (pools of dissolved fat) from a single obstructed meibomian lobule.

Condition/keywords: chalazion, lipogranulomatous reaction, meibomian lobule, situ

Feb 20 2019 by Lancaster Course in Ophthalmology

Verruca vulgaris of the lid showing acanthotic downgrowths of epithelium incurving toward the center.

Condition/keywords: acanthosis, epithelium, verruca vulgaris

Feb 20 2019 by Lancaster Course in Ophthalmology

Vacuolated epidermal cells containing basophilic intranuclear viral inclu­sions.

Condition/keywords: basophilic, epidermal cells

Feb 20 2019 by Lancaster Course in Ophthalmology

Molluscum contagiosum nodule on lid margin.

Condition/keywords: eye lid, molluscum contagiosum nodule

Feb 20 2019 by Lancaster Course in Ophthalmology

Thick, acanthotic lobules of epithelial cells with large, red cytoplasmic inclusions in the inner cells.

Condition/keywords: acanthosis, cytoplasmic inclusions, inner cells

Feb 20 2019 by Lancaster Course in Ophthalmology

Intraepidermal bulla in herpes zoster of the skin.

Condition/keywords: intraepidermal bulla

Feb 20 2019 by Lancaster Course in Ophthalmology

Fusion of infected epidermal cells form giant cells in the base of a lesion. Note the many intranuclear red inclusion bodies.

Condition/keywords: epidermal cells, giant cell, intranuclear red inclusion bodies

Feb 20 2019 by Lancaster Course in Ophthalmology

Symmetrical plaques of xanthelasma.

Condition/keywords: xanthelasma

Feb 20 2019 by Lancaster Course in Ophthalmology

Symmetrical plaques of xanthelasma.

Condition/keywords: symmetrical, xanthelasma

Feb 20 2019 by Lancaster Course in Ophthalmology

Bland, foamy macrophage accumulation in the dermis from xanthe­lasma. Note the single Touton giant cell below the center.

Condition/keywords: epidermis, giant cell, macrophage accumulation

Feb 20 2019 by Lancaster Course in Ophthalmology

Dermoid cyst of the left upper lid in an 11-month-old female (Courtesy of John Hoepner, M.D.)

Condition/keywords: cyst, eye lid

Feb 20 2019 by Lancaster Course in Ophthalmology

Keratinizing epithelium lining a dermoid cyst in the center, with keratin contents and a single large hair above. The connective tissue wall has a large hair follicle in it.

Condition/keywords: cyst, epithelium

Feb 20 2019 by Lancaster Course in Ophthalmology

Edge of three cystic cavities in a multilocular Moll cyst. The upper wall has a small area of "decapitate secretion" on the surface of the lining cells.

Condition/keywords: cyst, cystic cavities, decapitate secretion, multilocular

Feb 20 2019 by Lancaster Course in Ophthalmology

Hyperkeratotic squamous papilloma consisting of thin, keratin-covered fronds with dermal cores.

Condition/keywords: dermal cores, papilloma

Feb 20 2019 by Lancaster Course in Ophthalmology

Seborrheic keratoses with notable pigmentation. (Courtesy of Anthony Dark, M.D.)

Condition/keywords: Keratosis pilaris (KP)

Feb 20 2019 by Lancaster Course in Ophthalmology

Basal cell proliferation and keratin cysts of a typical seborrheic keratosis.

Condition/keywords: basal cell, cyst, Keratosis pilaris (KP)

Feb 20 2019 by Lancaster Course in Ophthalmology

Inverted follicular keratosis with thick, acanthotic, folded epithelium and keratin cysts.

Condition/keywords: acanthosis, cyst, epithelium

Feb 25 2019 by Lancaster Course in Ophthalmology

Center of epidermis has three "squamous eddies" of whorled squamous cells.

Condition/keywords: epidermis, squamous cells, squamous eddies

Feb 25 2019 by Lancaster Course in Ophthalmology

Keratoacanthoma of the lid. (Courtesy of Anthony Dark, M.D.)

Condition/keywords: keratoacanthoma, lids

Feb 25 2019 by Lancaster Course in Ophthalmology

Cup-shaped keratoacanthoma with central keratin plug.

Condition/keywords: keratin plug, keratoacanthoma

Feb 25 2019 by Lancaster Course in Ophthalmology

Senile keratosis has marked hyperkeratinization with columns of para­ keratosis and dermal infiltrate.

Condition/keywords: dermal infiltrate, hyperkeratinization, senile keratosis

Feb 25 2019 by Lancaster Course in Ophthalmology

A cutaneous horn arising from an inverted follicular keratosis.

Condition/keywords: cutaneous horn, inverted follicular keratosis

Feb 25 2019 by Lancaster Course in Ophthalmology

Two-layered sweat gland ducts in a tubular hidradenoma.

Condition/keywords: sweat gland ducts, tubular hidradenoma

Feb 25 2019 by Lancaster Course in Ophthalmology

Pilomatrixoma of the lid. (Courtesy of Schiele Brewer, M.D.)

Condition/keywords: lids, tumor

Feb 25 2019 by Lancaster Course in Ophthalmology

Cystic basal cell carcinoma arising in the skin of the lid, which was incorrectly diagnosed clinically.

Condition/keywords: basal cell, lids

Feb 25 2019 by Lancaster Course in Ophthalmology

Large nuclei of an ulceronodular basal cell carcinoma can be compared with the adjacent normal epithelial cell nuclei. Note the peripheral palisading of the nuclei around the edge of the tumor lobules.

Condition/keywords: basal cell carcinoma of eyelid, epithelial, nuclei

Feb 25 2019 by Lancaster Course in Ophthalmology

Cords of infiltrating basal cells in the dense, fibrous stroma of a morphea type basal cell carcinoma.

Condition/keywords: basal cell, basal cell carcinoma of eyelid, fibrous stroma

Feb 25 2019 by Lancaster Course in Ophthalmology

Basal cell carcinoma originating from five separate sites in the surface epithelium over the lacrimal punctum and canaliculus.

Condition/keywords: basal cell, canaliculus, epithelium, lacrimal punctum

Feb 25 2019 by Lancaster Course in Ophthalmology

Edge of squamous cell carcinoma of the skin showing sudden change from normal epithelium to infiltrating islands of large, malignant squamous cells.

Condition/keywords: epithelium, squamous cells

Feb 25 2019 by Lancaster Course in Ophthalmology

Cross-section of lid showing sebaceous carcinoma occupying the tarsal and middle compartments.

Condition/keywords: lids, tarsus

Feb 25 2019 by Lancaster Course in Ophthalmology

Lobule of with central foamy cells best seen in upper left.

Condition/keywords: lobule

Feb 25 2019 by Lancaster Course in Ophthalmology

Three nests of nevus cells at the tips of epithelial rete pegs, forming a "junctional" nevus.

Condition/keywords: epithelial, nevus

Feb 25 2019 by Lancaster Course in Ophthalmology

One nest of junctional nevus cells at the base of the epidermis and larger nodules of nevus cells in the dermis make this a "compound" nevus.

Condition/keywords: epidermis, junctional nevus

Feb 25 2019 by Lancaster Course in Ophthalmology

Inconspicuous spindle nevus cells and pigment in dense collagen of the dermis constitute a "blue" nevus.

Condition/keywords: collagen, nevus, pigment

Feb 25 2019 by Lancaster Course in Ophthalmology

Nest of atypical melanocytes resembling a junctional nevus at the edge of a superficial spreading melanoma in a 70-year-old female. Note the inflammatory cells in the dermis.

Condition/keywords: junctional nevus, melanocytes, melanoma