• OCT Montage: Choroidal Aspergilloma With Secondary Choroidal Neovascularization and Exudative Retinal Detachment

    Mar 21 2019 by Scott D Walter, MD, MSc

    Multimodal imaging of a transplant patient with disseminated Aspergillosis and vision loss in her left eye.

    Condition/keywords: choroidal neovascular membrane (CNVM), choroidal neovascularization (CNV), exudative detachment, focal chorioretinitis, fungal endophthalmitis, granulomatous choroiditis

  • FA: Choroidal Aspergilloma With Secondary Choroidal Neovascularization and Exudative Retinal Detachment

    Mar 21 2019 by Scott D Walter, MD, MSc

    Multimodal imaging of a transplant patient with disseminated Aspergillosis and vision loss in her left eye.

    Condition/keywords: choroidal neovascular membrane (CNVM), choroidal neovascularization (CNV), exudative detachment, focal chorioretinitis, fungal endophthalmitis, granulomatous choroiditis

  • ICG: Choroidal Aspergilloma With Secondary Choroidal Neovascularization and Exudative Retinal Detachment

    Mar 21 2019 by Scott D Walter, MD, MSc

    Multimodal imaging of a transplant patient with disseminated Aspergillosis and vision loss in her left eye.

    Condition/keywords: choroidal neovascular membrane (CNVM), choroidal neovascularization (CNV), exudative detachment, focal chorioretinitis, fungal endophthalmitis, granulomatous choroiditis

  • Posterior Vitreous Detachment

    Mar 21 2019 by Michael Politis, MD

    Intra-op image of a PVD induction using Kenalog in a retinal detachment after retained nuclear material

    Photographer: Michael Politis MD, McGill University, Montreal, Canada

    Imaging device: Karl Stroze

    Condition/keywords: kenalog, PVD induction, retinal detachment

  • Paracentral Acute Middle Maculopathy (PAMM)

    Mar 21 2019 by Jonathan Tsui, MD

    26-year-old female with hypertension presenting with chief complaint of "darkening" in her nasal visual field in the right eye. No flashes, floaters, or vision loss. Va 20/60 and nasal VF defect OD. SD-OCT demonstrated hyperreflectivity in the INL consistent with paracentral acute middle maculopathy. She was referred to her PCP for blood pressure optimization and a cardiovascular work-up. She returned for follow-up two months later with 20/80 OD, 20/20 OS. Repeat SD-OCT demonstrated inner retinal atrophy.

    Photographer: Zellers, Diane

    Condition/keywords: paracentral acute middle maculopathy

  • High-Risk Proliferative Diabetic Retinopathy

    Mar 20 2019 by Anfisa Ayalon

    Fundus fluorescein angiography of 58-year-old patient with left eye high-risk proliferative diabetic retinopathy. Note severe ischemia of retina, large areas of neovascularization elsewhere and preretinal hemorrhages.

    Photographer: Anfisa Ayalon, Meir Medical Center, Kfar Saba, Israel.

    Imaging device: California, Optos 200 DTX

    Condition/keywords: ischemia, neovascularization elsewhere (NVE), proliferative diabetic retinopathy (PDR), retina, subhyaloid hemorrhage

  • Slide 6-60

    Mar 20 2019 by Lancaster Course in Ophthalmology

    Retinoblastoma has extended out of the right eye into the orbit, causing proptosis and exposure keratitis of the eye.

    Condition/keywords: keratitis, proptosis, retinoblastoma

  • Slide 6-59

    Mar 20 2019 by Lancaster Course in Ophthalmology

    Hand-Schiiller-Christian disease. Dark pink areas represent the remain­ing sphenoid bone, which is almost completely replaced by atypical histiocytes (H&E x28). (Hogan, M. J., and Zimmerman, L. E. (eds.): Ophthalmic Pathology. W. B. Saunders, Philadelphia, 1968, p. 778.)

    Condition/keywords: Hand-Schiiller-Christian disease, histiocytes, sphenoid bone

  • Slide 6-58

    Mar 20 2019 by Lancaster Course in Ophthalmology

    Eosinophilic granuloma. Infiltration of orbital bone by eosinophils and large histiocytes (H&E x400).

    Condition/keywords: eosinophilic, eosinophils, histiocytes

  • Slide 6-57

    Mar 20 2019 by Lancaster Course in Ophthalmology

    Benign reactive lymphoid hyperplasia, showing monotonous infiltrate of mature lymphocytes with occasional mitotic figure (H&E x252).

    Condition/keywords: hyperplasia, lymphocytes

  • Slide 6-56

    Mar 20 2019 by Lancaster Course in Ophthalmology

    Granulocytic leukemia. Infiltration of orbital tissue by immature granu­locytes (H&E x640).

    Condition/keywords: leukemia

  • Slide 6-55

    Mar 20 2019 by Lancaster Course in Ophthalmology

    Burkitt's lymphoma. Undifferentiated, diffuse lymphosarcoma shows scattered macrophages engulfing nuclear debris, giving a "starry-sky" appearance to the tumor (H&E x252).

    Condition/keywords: Burkitt's lymphoma, lymphosarcoma

  • Slide 6-53

    Mar 20 2019 by Lancaster Course in Ophthalmology

    Inflammatory pseudotumor showing polymorphism and ancillary evi­dence of inflammation. Note presence of lymphocytes, plasma cells, and "juicy" capil­laries (H&E x252).

    Condition/keywords: lymphocytes, polymorphism, pseudotumor

  • Slide 6-52

    Mar 20 2019 by Lancaster Course in Ophthalmology

    Adenoid cystic carcinoma. Stroma between nests of neoplastic cells shows mild inflammatory reaction but is otherwise relatively acellular. No peripheral palisading is present, differentiating this tumor from similar-appearing basal cell carci­noma (H&E x40).

    Condition/keywords: carcinoma, neoplastic cells, stroma

  • Slide 6-51

    Mar 20 2019 by Lancaster Course in Ophthalmology

    Adenoid cystic carcinoma. A lacrimal gland is seen in the lower right corner. Nests of tumor cells show punched-out areas, giving a "Swiss cheese" appear­ance (H&E xl6).

    Condition/keywords: carcinoma, lacrimal gland

  • Slide 6-50

    Mar 20 2019 by Lancaster Course in Ophthalmology

    Malignant mixed tumor. Some areas resemble benign mixed tumors, while other areas are obviously adenocarcinoma (H&E xlOl).

    Condition/keywords: tumor

  • Slide 6-49

    Mar 20 2019 by Lancaster Course in Ophthalmology

    Benign mixed tumor. Cellular areas are composed of tubular epithelium, here showing some squamous metaplasia (H&E x252).

    Condition/keywords: metaplasia, tubular epithelium, tumor

  • Slide 6-48

    Mar 20 2019 by Lancaster Course in Ophthalmology

    Benign mixed tumor. Biphasic appearance is due to alternating, rela­tively acellular myxomatous spaces and cellular areas (H&E x40).

    Condition/keywords: tumor

  • Slide 6-47

    Mar 20 2019 by Lancaster Course in Ophthalmology

    Neurilemmoma. Antoni B pattern is composed of degenerated micro­cystoid areas of tumor (H&E xlOl).

    Condition/keywords: neurilemmoma

  • Slide 6-46

    Mar 20 2019 by Lancaster Course in Ophthalmology

    Neurilemmoma. Antoni A pattern under higher magnification (H&E xlOl).

    Condition/keywords: neurilemmoma

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