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Presumed Ocular Histoplasmosis Syndrome (POHS) with Choroidal Neovascular Membrane (CNVM) in the Right Eye: Treatment Response After One Dose of Anti-VEGF Therapy (Bevacizumab)
Oct 20 2026 by Fernando Pellerano, MD
A 48-year-old man presented with acute vision loss OD. BCVA was 20/80 OD and 20/20 OS. (A) Fundus examination of the right eye showed mild peripapillary atrophy (PPA), peripheral chorioretinal scars, and macular chorioretinal scarring with hemorrhage, concerning for CNVM. (B) Fundus autofluorescence (FAF) of the right eye showed hypoautofluorescence in areas of chorioretinal scarring. (C) Optical coherence tomography (OCT) of the right eye showed cystoid macular edema, subretinal hyperreflective material, and subretinal fluid. (D) OCT one month after a single dose of bevacizumab showed resolution of intraretinal fluid (IRF) and subretinal fluid (SRF), and visual acuity improved to 20/25. The patient was treated and extended with bevacizumab and faricimab-svoa, receiving a total of six intravitreal injections OD. Two years after discontinuing treatment, he remains free of active CNVM with preserved vision. The left eye showed histo spots and PPA without CNVM (not shown).
Photographer: Fernando Pellerano MD , Glick Eye Institute, Indiana University , School of Medicine
Imaging device: Heidelberg Spectralis
Condition/keywords: choroidal neovascular membrane (CNVM), presumed ocular histoplasmosis syndrome (POHS)
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Lyophilized Amniotic Membrane Graft for Traumatic Macular Hole
Oct 16 2026 by Mauricio Bayram-Suverza, MD
Fundus image of a 31-year-old man who underwent pars plana vitrectomy + ILM peeling + lyophilized amniotic membrane graft for a traumatic macular hole in the right eye.
Photographer: Mauricio Bayram-Suverza
Imaging device: TRC-50DX
Condition/keywords: Lyophilized Amniotic Membrane, traumatic macular hole, vitreoretinal surgery
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Scars and Memories of Impact: Chorioretinitis sclopetaria.
Oct 16 2026 by Sean Teixeira
A 14-year-old male presented with a history of ocular trauma to the left eye (OS) caused by a rubber projectile. Fundus photography revealed concentric chorioretinal scars consistent with choroidal ruptures surrounding the optic disc. A temporal lesion with hyperpigmented and hypopigmented areas and a cicatricial appearance was also observed. Diagnosis: Chorioretinitis sclopetaria.
Photographer: Sean Teixeira, Instituto de Oftalmologia do Rio de Janeiro
Imaging device: Clarus Zeiss
Condition/keywords: chorioretinal fold, chorioretinitis sclopetaria, trauma
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"Couched" Crystalline Lens
Oct 16 2026 by Max D Schlesinger, MD
Optos image of a spontaneously dislocated intact crystalline lens.
Photographer: Annalisa Lombardi
Condition/keywords: dislocated crystalline lens
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Dislocaed IOL in Retinitis Pigmentosa
Oct 15 2026 by Parnian Arjmand, MD, MSc, FRCSC, DABO, FASRS
A lone one piece acrylic IOL sits on an RP retina in the eye of a patient with an optically empty vitreoretinopathy
Photographer: Alex Amigleo
Condition/keywords: aphakia, sector retinitis pigmentosa
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YAG Hyaloidotomy
Oct 14 2026 by Seif Allah Anwar
Fundus photograph immediately after Nd:YAG laser hyaloidotomy for a dense premacular (subhyaloid) hemorrhage. The posterior hyaloid face over the hemorrhage has been punctured, and the trapped blood is now draining into the vitreous cavity. The residual boat-shaped pocket, with its sharp inferior border, outlines the original sub-hyaloid space.
Photographer: Seif Anwar FRCSEd , King Salman International University
Imaging device: TOPCON TRC DX50
Condition/keywords: YAG HYALOIDOTOMY
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Postoperative Image of Patient Operated for Giant Retinal Tear Detachment
Oct 13 2026 by PUJA NEGI
Postoperative photograph of patient operated for giant retinal tear detachment with attached retina and early emulsification of silicon oil
Photographer: Dr Margi Panchal
Condition/keywords: Giant Retinal Tear
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Preoperative Giant Retinal Tear with Nasal RD
Oct 13 2026 by PUJA NEGI
Young male patient with giant retinal tear
Photographer: Dr Margi Panchal
Condition/keywords: giant retinal tear
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The Retinal Hibiscus: Neovascularization of the Disc in CRAO
Oct 11 2026 by S. Natarajan, MD, FASRS, FRCS (GLASGOW) , FICO, D.Sc, FELA
A 59-year-old female presented with complaints of sudden loss of vision in the left eye since 1 year. On examination, visual acuity in the right eye (RE) was 20/20, while in the left eye (LE) it was perception of light (PL) with inaccurate projection. Anterior segment examination was unremarkable. Fundus examination of the LE revealed Neovascularization of the Disc (NVD) with scleroses retinal vessels, giving a "retinal hibiscus" appearance. Based on clinical findings, a probable diagnosis of Central Retinal Artery Occlusion (CRAO) with Ocular Ischemic Syndrome (OIS) was made. The patient was advised Pan-Retinal Photocoagulation (PRP) for the NVD and further systemic evaluation.
Photographer: MS. ASHWINI SUTAR
Imaging device: MIRANTE NIDEK
Condition/keywords: CRAO, neovascularization of the disc (NVD)
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Retinal Hemangioblastoma - Macular OCT
Oct 11 2026 by César Adrián Gómez Valdivia, MD
The foveal depression is lost and replaced by large central intraretinal cystoid spaces. Numerous hyperreflective foci in the outer retina, consistent with hard exudates, cast posterior shadows. Subretinal fluid extends beneath the fovea. The inner retinal surface is irregular, and the outer retinal bands are poorly defined in the subfoveal region.
Photographer: @eyemissu2
Imaging device: Heidelberg E.
Condition/keywords: vhl
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Retinal Hemangioblastoma - Raster OCT
Oct 11 2026 by César Adrián Gómez Valdivia, MD
The infrared reference image shows a round, dark, well-circumscribed lesion temporal to the macula, about 5 mm from the fovea. The B-scan through it reveals a dome-shaped elevation of the inner retina with a hyperreflective surface and dense posterior shadowing. The adjacent retina shows intraretinal cystoid spaces, hyperreflective foci consistent with hard exudates, and subretinal fluid.
Photographer: @eyemissu2
Imaging device: Heidelberg E.
Condition/keywords: OCT, tumor
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Retinal Hemangioblastoma - FA
Oct 11 2026 by César Adrián Gómez Valdivia, MD
The dilated superotemporal artery fills rapidly in the earliest frames, while the tortuous inferotemporal vein shows delayed laminar filling. The temporal peripheral lesion demonstrates intense early hyperfluorescence with progressive leakage that obscures its margins by one minute. Hypofluorescent areas with hyperfluorescent borders correspond to the chorioretinal scars. A round hyperfluorescent focus temporal to the fovea increases in intensity throughout the sequence.
Photographer: @eyemissu2
Imaging device: Clarus 700
Condition/keywords: FA late phase leakage
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Retinal Hemangioblastoma - RG
Oct 11 2026 by César Adrián Gómez Valdivia, MD
A markedly dilated and tortuous pair of retinal vessels arises from the optic disc and courses along the temporal arcades, converging on an elevated orange-red lesion in the temporal periphery. The lesion is surrounded by fibroglial tissue with preretinal traction. Lipid exudates are present in the macula and along the inferotemporal arcade. Pigmented chorioretinal scars from prior treatment are seen temporal to the macula and in the mid-periphery.
Photographer: @eyemissu2
Imaging device: OPTOS
Condition/keywords: retinal hemangioblastoma
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Diabetic Retinopathy
Oct 9 2026 by Andrea Arriola-Lopez, MD MSc
43-year-old male, BCVA 20/400, rubeosis iridis, PDR.
Photographer: Dr. Wendy Yax
Imaging device: EIDON UWF
Condition/keywords: Advanced diabetic eye disease, proliferative diabetic retinopathy (PDR)
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Acute Optic Nerve Head Avulsion With Secondary CRAO
Oct 8 2026 by Vishal Agrawal, MD, FRCS,FACS,FASRS
Fundus photograph of a 6 year old boy with sudden and complete loss of vision in left eye following blunt trauma. Fundus photography shows pre retinal blood surrounding the nerve suggestive of ONH avulsion. A fresh central retinal artery occlusion with stagnant blood column is also seen.
Photographer: Dr Gargi Sharma
Imaging device: Clarus 700
Condition/keywords: central retinal artery occlusion, optic nerve head avulsion
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Laser Barrage
Oct 6 2026 by Seif Allah Anwar
Widefield fundus image of the right eye shows a superotemporal retinal tear surrounded by a confluent, well-pigmented laser barrage, with dispersed vitreous haemorrhage settling inferiorly and a normal-appearing disc and macula.
Photographer: Seif Anwar FRCSEd , King Salman International University
Imaging device: CenterVue Eidon
Condition/keywords: BARRAGE LASER
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The Disappearing Gold: Oguchi Disease
Oct 6 2026 by Abhishek Karra, MS
Color fundus photographs before (upper panels) and after dark adaptation (lower panels) demonstrate the characteristic Mizuo–Nakamura phenomenon. The diffuse golden-yellow fundus sheen of Oguchi disease markedly diminishes following dark adaptation, revealing a relatively normal fundus appearance.
Photographer: Abhishek Karra
Imaging device: Zeiss Clarus
Condition/keywords: congenital stationary night blindness (CSNB), inherited retinal disease, Mizuo Nakamura Phenomenon, Oguchi's disease
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Extensive persistent avascular retina after anti-VEGF therapy for retinopathy of prematurity
Oct 5 2026 by Joaquín Sosa Lockward, MD
UltraWidefield fluorescein angiography demonstrates temporal avascular retina with associated vessels straightening without evidence of vascular leakage.
Condition/keywords: ROP
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Chronic retinal detachment in adult regressed retinopathy of prematurity previously treated with aggressive laser photocoagulation
Oct 5 2026 by Joaquín Sosa Lockward, MD
Color fundus photography demonstrates chronic retinal detachment in a 22-year-old patient with a history of extreme prematurity (born at 26 weeks of gestation) and regressed retinopathy of prematurity previously treated with extensive peripheral laser photocoagulation and primary scleral buckle. In the right eye, chronic subretinal fluid is observed dissecting toward the fovea, with a small atrophic retinal tear located at the border of the laser treated retina, corresponding to the site of the former ridge. In the left eye, retina appears attached under 5,000 Centistokes silicone oil tamponade following repair of recurrent retinal detachment.
Condition/keywords: ROP
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Chronic retinal detachment in adult regressed retinopathy of prematurity previously treated with aggressive laser photocoagulation
Oct 5 2026 by Joaquín Sosa Lockward, MD
Color fundus photography demonstrates chronic retinal detachment in a 22-year-old patient with a history of extreme prematurity (born at 26 weeks of gestation) and regressed retinopathy of prematurity previously treated with extensive peripheral laser photocoagulation and primary scleral buckle. In the right eye, chronic subretinal fluid is observed dissecting toward the fovea, with a small atrophic retinal tear located at the border of the laser treated retina, corresponding to the site of the former ridge. In the left eye, retina appears attached under 5,000 Centistokes silicone oil tamponade following repair of recurrent retinal detachment.
Condition/keywords: ROP

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