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Probable Cytomegalovirus Retinitis as the Presenting Manifestation of Newly Diagnosed HIV Infection
Sep 29 2026 by Pablo Angel García-Uribe, MD, PhD
A 45-year-old patient was referred to the Uveitis Service for presumed cytomegalovirus (CMV) retinitis in the right eye. Medical history was notable for chronic diarrhea, 15-kg unintentional weight loss, and hair loss. Visual acuity was 20/100 OD, improving to 20/50 with pinhole. Wide-field fundus photography showed a large area of necrotizing retinitis along the superior temporal vascular arcade, with retinal whitening, vascular sheathing, and intraretinal hemorrhages, while the macula remained uninvolved. The fellow eye was unremarkable. HIV-1 testing was positive, raising concern for an opportunistic retinal infection in the setting of immunosuppression. CMV retinitis was considered the leading diagnosis, and the patient was urgently referred for tertiary infectious disease and ophthalmologic management.
Photographer: David García-García, Optometrist, Clínica Oftalmológica Salauno, Mexico City
Imaging device: VISUCAM 524(Carl Zeiss Meditec AG, Jena, Germany)
Condition/keywords: cytomegalovirus (CMV), Cytomegalovirus Retinitis, infectious uveitis, retinitis
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Central Retinal Vein Occlusion - FA
Sep 29 2026 by César Adrián Gómez Valdivia, MD
Widefield fluorescein angiogram (Clarus, Zeiss) of the right eye, mid-phase, showing diffuse blocked fluorescence corresponding to extensive intraretinal hemorrhages in all four quadrants, venous wall staining, and areas of peripheral capillary nonperfusion with associated leakage, predominantly in the inferotemporal periphery.
Photographer: @eyemissu2
Imaging device: Clarus 700
Condition/keywords: central retinal vein occlusion (CRVO)
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Central Retinal Vein Occlusion - RG
Sep 29 2026 by César Adrián Gómez Valdivia, MD
Widefield color fundus photograph (Clarus, Zeiss) of the right eye showing diffuse four-quadrant retinal hemorrhages (dot, blot, and flame-shaped) radiating from the optic disc, along with venous tortuosity and dilation and mild disc hyperemia. Findings are consistent with an acute central retinal vein occlusion.
Photographer: @eyemissu2
Imaging device: Clarus 700
Condition/keywords: central retinal vein occlusion
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Central Retinal Vein Occlusion - OCT
Sep 29 2026 by César Adrián Gómez Valdivia, MD
Horizontal macular OCT B-scan of the right eye showing marked cystoid macular edema with large intraretinal cystic spaces spanning the outer and inner retinal layers, diffuse retinal thickening, and disruption of the normal foveal contour
Photographer: @eyemissu2
Imaging device: Heidelberg E.
Condition/keywords: central retinal vein occlusion
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Pericentral Retinitis Pigmentosa - Visual-Field
Sep 29 2026 by César Adrián Gómez Valdivia, MD
Goldmann kinetic perimetry of the right eye demonstrating a dense annular (ring) scotoma affecting the mid-peripheral field, with a relatively preserved central island and residual peripheral isopters (III4e and II4e). This ring-scotoma pattern is characteristic of pericentral retinitis pigmentosa.
Photographer: @eyemissu2
Condition/keywords: pericentral retinitis pigmentosa, retinitis pigmentosa, retinitis pigmentosa (RP) dystrophy
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Pericentral Retinitis Pigmentosa - OCT
Sep 29 2026 by César Adrián Gómez Valdivia, MD
Horizontal macular OCT B-scan of the right eye showing preservation of the foveal contour and ellipsoid zone centrally, with progressive perifoveal attenuation and loss of the ellipsoid and interdigitation zones extending toward the pericentral retina. Outer nuclear layer thinning is noted outside the fovea, consistent with pericentral photoreceptor degeneration.
Photographer: @eyemissu2
Imaging device: Heidelberg E.
Condition/keywords: pigmentosa
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Pericentral Retinitis Pigmentosa - Ultra-Wide-FAF
Sep 29 2026 by César Adrián Gómez Valdivia, MD
Ultra-widefield autofluorescence image of the right eye demonstrating an oval, pericentral zone of mottled hypo- and hyperautofluorescence encircling the macula, with a discrete hyperautofluorescent ring at its inner border and relative preservation of both the central macula and far peripheral retina. Findings support a pericentral pattern of retinal degeneration.
Photographer: @eyemissu2
Imaging device: OPTOS
Condition/keywords: retinitis
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Pericentral Retinitis Pigmentosa - FAF
Sep 29 2026 by César Adrián Gómez Valdivia, MD
Fundus autofluorescence image (Clarus, Zeiss) of the right eye showing a well-defined parafoveal hyperautofluorescent ring encircling a relatively preserved central macula, surrounded by an annular zone of mottled hypo- and hyperautofluorescence corresponding to pericentral pigmentary degeneration. The far periphery is relatively spared.
Photographer: @eyemissu2
Imaging device: Clarus 700
Condition/keywords: RETINITIS PIGMENTOSA
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Pericentral Retinitis Pigmentosa - RG
Sep 29 2026 by César Adrián Gómez Valdivia, MD
Widefield color fundus photograph (Clarus, Zeiss) of the right eye showing a pericentral band of retinal pigment epithelium mottling and scattered bone-spicule-like pigment clumping surrounding the posterior pole, with relative sparing of the far periphery. The optic disc and retinal vasculature appear normal in caliber.
Photographer: @eyemissu2
Imaging device: Clarus 700
Condition/keywords: pericentral retinitis pigmentosa, retinitis pigmentosa (RP) dystrophy
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Ciloretinal Artery Occlusion - FA
Sep 29 2026 by César Adrián Gómez Valdivia, MD
Widefield fluorescein angiogram (Clarus, Zeiss) of the left eye showing delayed/absent filling of the cilioretinal artery with a corresponding hypofluorescent wedge-shaped area adjacent to the disc. Delayed filling is also noted in the inferotemporal retinal arterial branch. Findings support the diagnosis of cilioretinal artery occlusion with associated inferotemporal arterial filling delay.
Photographer: @eyemissu2
Imaging device: Clarus 700
Condition/keywords: cilioretinal artery occlusion
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Ciloretinal Artery Occlusion - OCT
Sep 29 2026 by César Adrián Gómez Valdivia, MD
Horizontal OCT B-scan through the optic disc showing focal thickening and hyperreflectivity of the inner retinal layers with posterior shadowing, corresponding to the area of ischemic retinal whitening seen clinically. The outer retinal layers and RPE remain relatively preserved. Appearance is consistent with acute inner retinal ischemia from cilioretinal artery occlusion.
Photographer: @eyemissu2
Imaging device: Clarus 700
Condition/keywords: ischemia, OCT
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Ciloretinal Artery Occlusion - RG
Sep 29 2026 by César Adrián Gómez Valdivia, MD
Widefield color fundus photograph (Clarus, Zeiss) of the left eye showing a well-demarcated, wedge-shaped area of retinal whitening (ischemic edema) adjacent to the optic disc, following the distribution of the cilioretinal artery. The remaining retinal vasculature and posterior pole appear otherwise unremarkable. Findings are consistent with an acute cilioretinal artery occlusion.
Photographer: @eyemissu2
Imaging device: Clarus 700
Condition/keywords: cilioretinal artery
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Valsalva Retinopathy
Sep 29 2026 by Kimberly Wakester, COA, OCT-C
Optos RGB image of a 29-year-old male with a large subILM hemorrhage in the left eye. Patient was was seen in the ER for central haze in vision of the left eye following strenuous pushups. Clinical findings are consistent with Valsalva Retinopathy which is not uncommon following strenuous activities. Patient was advised to return in 2-3 weeks for a follow up exam and repeat Fundus photos for documentation and continued monitoring.
Photographer: Kimberly Wakester, COA, CRT, OCT-C
Imaging device: Optos California
Condition/keywords: large subILM, left eye, valsalva retinopathy
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Retinal Detachment With Single Break
Sep 29 2026 by Kimberly Wakester, COA, OCT-C
Optomap RG image of a 56-year-old woman with a retinal detachment with a lattice-associated retinal tear in the right eye. Surgery was recommended. Patient is to continue follow up care post operatively.
Photographer: Kimberly Wakester, COA, CRT, OCT-C
Imaging device: Optos California
Condition/keywords: horseshoe tear, lattice degeneration, Retinal Detachment, retinal tear, right eye
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Autofluorescence Image of a Retinal Detachment With Single Break
Sep 29 2026 by Kimberly Wakester, COA, OCT-C
Optomap AF image of a 56-year-old woman with a retinal detachment with a lattice-associated retinal tear in the right eye.
Photographer: Kimberly Wakester, COA, CRT, OCT-C
Imaging device: Optos California
Condition/keywords: horseshoe tear, lattice degeneration, Retinal Detachment, retinal tear, right eye
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The Ischemic Landscape of Eales Sisease
Sep 29 2026 by Abhishek Karra, MS
A 30-year-old male patient presented with complaints of floaters in his left eye. On examination, a pre-retinal hemorrhage was noted superior to the disc. On FFA, we can see a beautiful tuft of neovascularization along with blocked fluorescence due to pre-retinal hemorrhage. Also we can note the extensive capillary non perfusion areas in the temporal and superior periphery.
Photographer: Abhishek Karra
Imaging device: Zeiss Clarus
Condition/keywords: Eales disease, FFA, neovascularization elsewhere (NVE)
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OCTA-BRAO
Sep 27 2026 by Thirumalesh Mochi Basavaraj, MD
A OCTA image of a 40-year-old patient who came with sudden onset blurring of visual acuity. The ultra-widefield OCTA image shows Inferotemporal Arterial occlusion with pruning of the arterial shadow and corresponding loss of capillary circulation.
Photographer: Thirumalesh Mochi Basavaraj
Imaging device: Dream OCTA , Intalight system
Condition/keywords: BRAO
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Coats Behind the Curtain
Sep 25 2026 by Resham Khatri, M. S. Ophthalmology, MBBS
Fundus image of a 13-year-old female presenting with gradual, progressive and profound loss of vision in right eye
Photographer: Dr Resham Khatri
Imaging device: Optos
Condition/keywords: Coat's disease, Coats' disease, creamy yellow exudates, diffuse lipid exudate
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Ciliary Body Cyst
Sep 25 2026 by Oftalmontt Clínica Láser
A middle-aged male patient who underwent LASEK laser refractive surgery attended a postoperative follow-up visit, during which the physician detected iris bulging and subsequently ordered OCT and UBM. The images show iris bulging in the left eye, where UBM visualizes the presence of multiple ciliary body cysts, suggesting that aqueous humor entrapment has occurred.
Photographer: Ophthalmic Medical Technologist
Imaging device: Avanti XR AngioVue OptoVue and UBM ABSolu
Condition/keywords: ciliary body cyst
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Florid-NVI
Sep 24 2026 by Thirumalesh Mochi Basavaraj, MD
Anterior segment photograph of a 50-year-old man who had come for diabetic retinopathy screening but found to have both eye Proliferative diabetic retinopathy with Flroid iris Neo vascularization with ectropion uvea
Photographer: Puttaswamy
Condition/keywords: iris neovascularization, neovascular glaucoma

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