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Oct 11 2026 by César Adrián Gómez Valdivia, MD

The foveal depression is lost and replaced by large central intraretinal cystoid spaces. Numerous hyperreflective foci in the outer retina, consistent with hard exudates, cast posterior shadows. Subretinal fluid extends beneath the fovea. The inner retinal surface is irregular, and the outer retinal bands are poorly defined in the subfoveal region.

Photographer: @eyemissu2

Imaging device: Heidelberg E.

Condition/keywords: vhl

Oct 11 2026 by César Adrián Gómez Valdivia, MD

The infrared reference image shows a round, dark, well-circumscribed lesion temporal to the macula, about 5 mm from the fovea. The B-scan through it reveals a dome-shaped elevation of the inner retina with a hyperreflective surface and dense posterior shadowing. The adjacent retina shows intraretinal cystoid spaces, hyperreflective foci consistent with hard exudates, and subretinal fluid.

Photographer: @eyemissu2

Imaging device: Heidelberg E.

Condition/keywords: OCT, tumor

Oct 11 2026 by César Adrián Gómez Valdivia, MD

The dilated superotemporal artery fills rapidly in the earliest frames, while the tortuous inferotemporal vein shows delayed laminar filling. The temporal peripheral lesion demonstrates intense early hyperfluorescence with progressive leakage that obscures its margins by one minute. Hypofluorescent areas with hyperfluorescent borders correspond to the chorioretinal scars. A round hyperfluorescent focus temporal to the fovea increases in intensity throughout the sequence.

Photographer: @eyemissu2

Imaging device: Clarus 700

Condition/keywords: FA late phase leakage

Oct 11 2026 by César Adrián Gómez Valdivia, MD

A markedly dilated and tortuous pair of retinal vessels arises from the optic disc and courses along the temporal arcades, converging on an elevated orange-red lesion in the temporal periphery. The lesion is surrounded by fibroglial tissue with preretinal traction. Lipid exudates are present in the macula and along the inferotemporal arcade. Pigmented chorioretinal scars from prior treatment are seen temporal to the macula and in the mid-periphery.

Photographer: @eyemissu2

Imaging device: OPTOS

Condition/keywords: retinal hemangioblastoma

Oct 9 2026 by Andrea Arriola-Lopez, MD MSc

43-year-old male, BCVA 20/400, rubeosis iridis, PDR.

Photographer: Dr. Wendy Yax

Imaging device: EIDON UWF

Condition/keywords: Advanced diabetic eye disease, proliferative diabetic retinopathy (PDR)

Oct 8 2026 by Vishal Agrawal, MD, FRCS,FACS,FASRS

Fundus photograph of a 6 year old boy with sudden and complete loss of vision in left eye following blunt trauma. Fundus photography shows pre retinal blood surrounding the nerve suggestive of ONH avulsion. A fresh central retinal artery occlusion with stagnant blood column is also seen.

Photographer: Dr Gargi Sharma

Imaging device: Clarus 700

Condition/keywords: central retinal artery occlusion, optic nerve head avulsion

Oct 6 2026 by Seif Allah Anwar

Widefield fundus image of the right eye shows a superotemporal retinal tear surrounded by a confluent, well-pigmented laser barrage, with dispersed vitreous haemorrhage settling inferiorly and a normal-appearing disc and macula.

Photographer: Seif Anwar FRCSEd , King Salman International University

Imaging device: CenterVue Eidon

Condition/keywords: BARRAGE LASER

Oct 6 2026 by Abhishek Karra, MS

Color fundus photographs before (upper panels) and after dark adaptation (lower panels) demonstrate the characteristic Mizuo–Nakamura phenomenon. The diffuse golden-yellow fundus sheen of Oguchi disease markedly diminishes following dark adaptation, revealing a relatively normal fundus appearance.

Photographer: Abhishek Karra

Imaging device: Zeiss Clarus

Condition/keywords: congenital stationary night blindness (CSNB), inherited retinal disease, Mizuo Nakamura Phenomenon, Oguchi's disease

Oct 5 2026 by Joaquín Sosa Lockward, MD

UltraWidefield fluorescein angiography demonstrates temporal avascular retina with associated vessels straightening without evidence of vascular leakage.

Condition/keywords: ROP

Oct 5 2026 by Joaquín Sosa Lockward, MD

Color fundus photography demonstrates chronic retinal detachment in a 22-year-old patient with a history of extreme prematurity (born at 26 weeks of gestation) and regressed retinopathy of prematurity previously treated with extensive peripheral laser photocoagulation and primary scleral buckle. In the right eye, chronic subretinal fluid is observed dissecting toward the fovea, with a small atrophic retinal tear located at the border of the laser treated retina, corresponding to the site of the former ridge. In the left eye, retina appears attached under 5,000 Centistokes silicone oil tamponade following repair of recurrent retinal detachment.

Condition/keywords: ROP

Oct 5 2026 by Joaquín Sosa Lockward, MD

Color fundus photography demonstrates chronic retinal detachment in a 22-year-old patient with a history of extreme prematurity (born at 26 weeks of gestation) and regressed retinopathy of prematurity previously treated with extensive peripheral laser photocoagulation and primary scleral buckle. In the right eye, chronic subretinal fluid is observed dissecting toward the fovea, with a small atrophic retinal tear located at the border of the laser treated retina, corresponding to the site of the former ridge. In the left eye, retina appears attached under 5,000 Centistokes silicone oil tamponade following repair of recurrent retinal detachment.

Condition/keywords: ROP

Sep 30 2026 by Seif Allah Anwar

This FFA demonstrates a linear hyperfluorescent track in a 54-year-old male ; extending from the optic disc along the superior temporal vascular arcade toward the peripheral retina. The track is associated with focal areas of late staining/leakage and adjacent chorioretinal atrophic changes, giving the appearance of a migrating/worm-like track.

Photographer: Seif Anwar , king Salman International University

Imaging device: TOPCON 50D X

Condition/keywords: diffuse unilateral subacute neuroretinitis (DUSN)

Sep 29 2026 by Pablo Angel García-Uribe, MD, PhD

A 45-year-old patient was referred to the Uveitis Service for presumed cytomegalovirus (CMV) retinitis in the right eye. Medical history was notable for chronic diarrhea, 15-kg unintentional weight loss, and hair loss. Visual acuity was 20/100 OD, improving to 20/50 with pinhole. Wide-field fundus photography showed a large area of necrotizing retinitis along the superior temporal vascular arcade, with retinal whitening, vascular sheathing, and intraretinal hemorrhages, while the macula remained uninvolved. The fellow eye was unremarkable. HIV-1 testing was positive, raising concern for an opportunistic retinal infection in the setting of immunosuppression. CMV retinitis was considered the leading diagnosis, and the patient was urgently referred for tertiary infectious disease and ophthalmologic management.

Photographer: David García-García, Optometrist, Clínica Oftalmológica Salauno, Mexico City

Imaging device: VISUCAM 524(Carl Zeiss Meditec AG, Jena, Germany)

Condition/keywords: cytomegalovirus (CMV), Cytomegalovirus Retinitis, infectious uveitis, retinitis

Sep 29 2026 by César Adrián Gómez Valdivia, MD

Widefield fluorescein angiogram (Clarus, Zeiss) of the right eye, mid-phase, showing diffuse blocked fluorescence corresponding to extensive intraretinal hemorrhages in all four quadrants, venous wall staining, and areas of peripheral capillary nonperfusion with associated leakage, predominantly in the inferotemporal periphery.

Photographer: @eyemissu2

Imaging device: Clarus 700

Condition/keywords: central retinal vein occlusion (CRVO)

Sep 29 2026 by César Adrián Gómez Valdivia, MD

Widefield color fundus photograph (Clarus, Zeiss) of the right eye showing diffuse four-quadrant retinal hemorrhages (dot, blot, and flame-shaped) radiating from the optic disc, along with venous tortuosity and dilation and mild disc hyperemia. Findings are consistent with an acute central retinal vein occlusion.

Photographer: @eyemissu2

Imaging device: Clarus 700

Condition/keywords: central retinal vein occlusion

Sep 29 2026 by César Adrián Gómez Valdivia, MD

Horizontal macular OCT B-scan of the right eye showing marked cystoid macular edema with large intraretinal cystic spaces spanning the outer and inner retinal layers, diffuse retinal thickening, and disruption of the normal foveal contour

Photographer: @eyemissu2

Imaging device: Heidelberg E.

Condition/keywords: central retinal vein occlusion

Sep 29 2026 by César Adrián Gómez Valdivia, MD

Goldmann kinetic perimetry of the right eye demonstrating a dense annular (ring) scotoma affecting the mid-peripheral field, with a relatively preserved central island and residual peripheral isopters (III4e and II4e). This ring-scotoma pattern is characteristic of pericentral retinitis pigmentosa.

Photographer: @eyemissu2

Condition/keywords: pericentral retinitis pigmentosa, retinitis pigmentosa, retinitis pigmentosa (RP) dystrophy

Sep 29 2026 by César Adrián Gómez Valdivia, MD

Horizontal macular OCT B-scan of the right eye showing preservation of the foveal contour and ellipsoid zone centrally, with progressive perifoveal attenuation and loss of the ellipsoid and interdigitation zones extending toward the pericentral retina. Outer nuclear layer thinning is noted outside the fovea, consistent with pericentral photoreceptor degeneration.

Photographer: @eyemissu2

Imaging device: Heidelberg E.

Condition/keywords: pigmentosa

Sep 29 2026 by César Adrián Gómez Valdivia, MD

Ultra-widefield autofluorescence image of the right eye demonstrating an oval, pericentral zone of mottled hypo- and hyperautofluorescence encircling the macula, with a discrete hyperautofluorescent ring at its inner border and relative preservation of both the central macula and far peripheral retina. Findings support a pericentral pattern of retinal degeneration.

Photographer: @eyemissu2

Imaging device: OPTOS

Condition/keywords: retinitis

Sep 29 2026 by César Adrián Gómez Valdivia, MD

Fundus autofluorescence image (Clarus, Zeiss) of the right eye showing a well-defined parafoveal hyperautofluorescent ring encircling a relatively preserved central macula, surrounded by an annular zone of mottled hypo- and hyperautofluorescence corresponding to pericentral pigmentary degeneration. The far periphery is relatively spared.

Photographer: @eyemissu2

Imaging device: Clarus 700

Condition/keywords: RETINITIS PIGMENTOSA