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Mar 21 2019 by Scott D Walter, MD, MSc

Multimodal imaging of a transplant patient with disseminated Aspergillosis and vision loss in her left eye.

Condition/keywords: choroidal neovascular membrane (CNVM), choroidal neovascularization (CNV), exudative detachment, focal chorioretinitis, fungal endophthalmitis, granulomatous choroiditis

Mar 21 2019 by Scott D Walter, MD, MSc

Multimodal imaging of a transplant patient with disseminated Aspergillosis and vision loss in her left eye.

Condition/keywords: choroidal neovascular membrane (CNVM), choroidal neovascularization (CNV), exudative detachment, focal chorioretinitis, fungal endophthalmitis, granulomatous choroiditis

Mar 21 2019 by Scott D Walter, MD, MSc

Multimodal imaging of a transplant patient with disseminated Aspergillosis and vision loss in her left eye.

Condition/keywords: choroidal neovascular membrane (CNVM), choroidal neovascularization (CNV), exudative detachment, focal chorioretinitis, fungal endophthalmitis, granulomatous choroiditis

Mar 21 2019 by Michael Politis, MD

Intra-op image of a PVD induction using Kenalog in a retinal detachment after retained nuclear material

Photographer: Michael Politis MD, McGill University, Montreal, Canada

Imaging device: Karl Stroze

Condition/keywords: kenalog, PVD induction, retinal detachment

Mar 21 2019 by Jonathan Tsui, MD

26-year-old female with hypertension presenting with chief complaint of "darkening" in her nasal visual field in the right eye. No flashes, floaters, or vision loss. Va 20/60 and nasal VF defect OD. SD-OCT demonstrated hyperreflectivity in the INL consistent with paracentral acute middle maculopathy. She was referred to her PCP for blood pressure optimization and a cardiovascular work-up. She returned for follow-up two months later with 20/80 OD, 20/20 OS. Repeat SD-OCT demonstrated inner retinal atrophy.

Photographer: Zellers, Diane

Condition/keywords: paracentral acute middle maculopathy

Mar 20 2019 by Anfisa Ayalon

Fundus fluorescein angiography of 58-year-old patient with left eye high-risk proliferative diabetic retinopathy. Note severe ischemia of retina, large areas of neovascularization elsewhere and preretinal hemorrhages.

Photographer: Anfisa Ayalon, Meir Medical Center, Kfar Saba, Israel.

Imaging device: California, Optos 200 DTX

Condition/keywords: ischemia, neovascularization elsewhere (NVE), proliferative diabetic retinopathy (PDR), retina, subhyaloid hemorrhage

Mar 20 2019 by Lancaster Course in Ophthalmology

Retinoblastoma has extended out of the right eye into the orbit, causing proptosis and exposure keratitis of the eye.

Condition/keywords: keratitis, proptosis, retinoblastoma

Mar 20 2019 by Lancaster Course in Ophthalmology

Hand-Schiiller-Christian disease. Dark pink areas represent the remain­ing sphenoid bone, which is almost completely replaced by atypical histiocytes (H&E x28). (Hogan, M. J., and Zimmerman, L. E. (eds.): Ophthalmic Pathology. W. B. Saunders, Philadelphia, 1968, p. 778.)

Condition/keywords: Hand-Schiiller-Christian disease, histiocytes, sphenoid bone

Mar 20 2019 by Lancaster Course in Ophthalmology

Eosinophilic granuloma. Infiltration of orbital bone by eosinophils and large histiocytes (H&E x400).

Condition/keywords: eosinophilic, eosinophils, histiocytes

Mar 20 2019 by Lancaster Course in Ophthalmology

Benign reactive lymphoid hyperplasia, showing monotonous infiltrate of mature lymphocytes with occasional mitotic figure (H&E x252).

Condition/keywords: hyperplasia, lymphocytes

Mar 20 2019 by Lancaster Course in Ophthalmology

Granulocytic leukemia. Infiltration of orbital tissue by immature granu­locytes (H&E x640).

Condition/keywords: leukemia

Mar 20 2019 by Lancaster Course in Ophthalmology

Burkitt's lymphoma. Undifferentiated, diffuse lymphosarcoma shows scattered macrophages engulfing nuclear debris, giving a "starry-sky" appearance to the tumor (H&E x252).

Condition/keywords: Burkitt's lymphoma, lymphosarcoma

Mar 20 2019 by Lancaster Course in Ophthalmology

Inflammatory pseudotumor showing polymorphism and ancillary evi­dence of inflammation. Note presence of lymphocytes, plasma cells, and "juicy" capil­laries (H&E x252).

Condition/keywords: lymphocytes, polymorphism, pseudotumor

Mar 20 2019 by Lancaster Course in Ophthalmology

Adenoid cystic carcinoma. Stroma between nests of neoplastic cells shows mild inflammatory reaction but is otherwise relatively acellular. No peripheral palisading is present, differentiating this tumor from similar-appearing basal cell carci­noma (H&E x40).

Condition/keywords: carcinoma, neoplastic cells, stroma

Mar 20 2019 by Lancaster Course in Ophthalmology

Adenoid cystic carcinoma. A lacrimal gland is seen in the lower right corner. Nests of tumor cells show punched-out areas, giving a "Swiss cheese" appear­ance (H&E xl6).

Condition/keywords: carcinoma, lacrimal gland

Mar 20 2019 by Lancaster Course in Ophthalmology

Malignant mixed tumor. Some areas resemble benign mixed tumors, while other areas are obviously adenocarcinoma (H&E xlOl).

Condition/keywords: tumor

Mar 20 2019 by Lancaster Course in Ophthalmology

Benign mixed tumor. Cellular areas are composed of tubular epithelium, here showing some squamous metaplasia (H&E x252).

Condition/keywords: metaplasia, tubular epithelium, tumor

Mar 20 2019 by Lancaster Course in Ophthalmology

Benign mixed tumor. Biphasic appearance is due to alternating, rela­tively acellular myxomatous spaces and cellular areas (H&E x40).

Condition/keywords: tumor

Mar 20 2019 by Lancaster Course in Ophthalmology

Neurilemmoma. Antoni B pattern is composed of degenerated micro­cystoid areas of tumor (H&E xlOl).

Condition/keywords: neurilemmoma

Mar 20 2019 by Lancaster Course in Ophthalmology

Neurilemmoma. Antoni A pattern under higher magnification (H&E xlOl).

Condition/keywords: neurilemmoma