Browse. Share. Learn.

Sep 2 2026 by Pablo Angel García-Uribe, MD, PhD

Case description A 63-year-old woman with neovascular age-related macular degeneration (nAMD) in the right eye underwent a loading course of three intravitreal aflibercept injections. Following treatment, she developed a large retinal pigment epithelium (RPE) tear involving nearly the entire macular area, with marked retraction and folding of the detached RPE. Spectral-domain OCT Spectral-domain optical coherence tomography demonstrates abrupt interruption of the RPE layer with extensive retraction of the torn RPE. The displaced RPE forms a prominent, sharply elevated hyperreflective fold with dense posterior shadowing. Adjacent areas lacking RPE show increased optical transmission into the choroid. The folded tissue creates a striking double-layered configuration, resembling a folded “quesadilla,” corresponding to the markedly retracted edges of the large RPE tear.

Photographer: David García-García, Optometrist, Clínica Oftalmológica Salauno, Mexico City

Imaging device: Fundus camera VISUCAM 524(Carl Zeiss Meditec AG, Jena, Germany)

Condition/keywords: RPE Rip, RPE-Rip

Sep 2 2026 by Pablo Angel García-Uribe, MD, PhD

Case description A 63-year-old woman with neovascular age-related macular degeneration (nAMD) in the right eye underwent a loading course of three intravitreal aflibercept injections. Following treatment, she developed a large retinal pigment epithelium (RPE) tear involving nearly the entire macular area, with marked retraction and folding of the detached RPE. Fundus autofluorescence Fundus autofluorescence demonstrates a large area of marked hypoautofluorescence corresponding to loss of the RPE and exposure of the underlying tissue. In contrast, the retracted and folded RPE appears markedly hyperautofluorescent, sharply delineating the displaced pigment epithelium and emphasizing the extensive configuration of the tear.

Photographer: David García-García, Optometrist, Clínica Oftalmológica Salauno, Mexico City

Imaging device: Fundus camera VISUCAM 524(Carl Zeiss Meditec AG, Jena, Germany)

Condition/keywords: RPE Rip, RPE-Rip, wet age-related macular degeneration (wet AMD)

Sep 2 2026 by Pablo Angel García-Uribe, MD, PhD

Case description A 63-year-old woman with neovascular age-related macular degeneration (nAMD) in the right eye underwent a loading course of three intravitreal aflibercept injections. Following treatment, she developed a large retinal pigment epithelium (RPE) tear involving nearly the entire macular area, with marked retraction and folding of the detached RPE. Color fundus photograph Color fundus photography of the right eye shows a broad area of macular RPE disruption and retraction. The torn RPE is displaced and folded upon itself within the central macula, producing a well-demarcated elevated pigmented lesion surrounded by an area of relative RPE absence.

Photographer: David García-García, Optometrist, Clínica Oftalmológica Salauno, Mexico City

Imaging device: Fundus camera VISUCAM 524(Carl Zeiss Meditec AG, Jena, Germany)

Condition/keywords: RPE Rip, RPE-Rip, wet age-related macular degeneration (wet AMD)

Aug 31 2026 by Vicente Nicanor Mancilla Guerrero

Fundus examination of a young female patient with type 1 diabetes mellitus, with a diabetes duration of over 10 years, currently diagnosed with proliferative diabetic retinopathy. Laser spots can be seen in the periphery, multiple hemorrhagic foci in all four quadrants, and exudation.

Photographer: Vicente Mancilla G, Ophthalmic Medical Technologist

Imaging device: Compass CenterVue

Condition/keywords: diabetes

Aug 28 2026 by Marin Shehata

77-year-old male with significant inflammatory of the blood vessels inside the retina.

Photographer: Marin Shehata, Retina consultants of Carolina

Condition/keywords: Retinal Vasculitis

Aug 27 2026 by Poornachandra B, MS, FVRS

Wide-field FAF shows multiple discrete and confluent hyperautofluorescent vitelliform deposits involving the posterior pole and peripapillary region, with surrounding mottled RPE hypoautofluorescence, consistent with Autosomal Recessive Bestrophinopathy, reflecting widespread lipofuscin accumulation with chronic RPE dysfunction.

Photographer: Mr Dhikshith

Condition/keywords: autofluorescence imaging, Autosomal recessive bestrophinopathy, inherited retinal disease

Aug 26 2026 by Muthanna B Yasir, MD,CAB(Ophth),JBO,FICO,MRCS

This video demonstrates Internal Limiting Membrane (ILM) peeling directly on a mobile, detached retina without PFCL (Decalin) stabilization—a technique often necessary in high myopic eyes with posterior staphyloma or extensive chorioretinal atrophy.

Photographer: Muthanna Basheer Yasir

Condition/keywords: ILM peeling, IRD

Aug 25 2026 by Dallin Milner

Monocular pediatric patient who had lost vision due to chronic retinal detachment from FEVR OD who presented with decreased vision OS. The patient was found to have a combined tractional and rhegmatogenous detachment that was repaired with a 510 sponge.

Condition/keywords: familial exudative vitreoretinopathy (FEVR), pediatric retinal detachment, pediatric scleral buckle

Aug 25 2026 by Dallin Milner

Monocular pediatric patient who had lost vision due to chronic retinal detachment from FEVR OD who presented with decreased vision OS. The patient was found to have a combined tractional and rhegmatogenous detachment that was repaired with a 510 sponge.

Condition/keywords: FEVR, pediatric retinal detachment, pediatric scleral buckle

Aug 25 2026 by Dallin Milner

Pediatric dialysis treated with scleral buckle

Condition/keywords: pediatric retinal detachment, pediatric scleral buckle

Aug 25 2026 by Dallin Milner

s/p buckle

Condition/keywords: Pediatric PVR Detachment, pediatric scleral buckle

Aug 24 2026 by SHAILEEN PARIKH, MS, DO, FMRF

Fundus photo of a 75-year old man presented with a large macular hole of 1770 microns without any history of trauma.

Photographer: Dr. Shaileen Parikh, Eye & U Clinic, Nairobi

Condition/keywords: Macular hole

Aug 24 2026 by Ray Johnson

An OCT image of a 50 year-old female following a repair of a macula-off retinal detachment; demonstrating a superior reflection of the fovea caused by the residual intraocular gas bubble.

Photographer: Andy Quinn, Great Lakes Eye Care

Imaging device: Optovue

Condition/keywords: fovea

Aug 24 2026 by Ray Johnson

An OCT image of a 50 year-old female following a repair of a macula-off retinal detachment, demonstrating a superior reflection of the fovea caused by the residual intraocular gas bubble.

Photographer: Andy Quinn, Great Lakes Eye Care

Imaging device: Optovue

Condition/keywords: fovea, gas bubble

Aug 21 2026 by Shikhara Vijayan

A 73 year-old woman with right eye Vitreomacular Traction and Tractional Schisis, later underwent Vitrectomy surgery.

Photographer: Ansif

Condition/keywords: vitreomacular traction (VMT)

Aug 20 2026 by Mauricio Bayram-Suverza, MD

Fundus photograph of an 80 year-old female patient under follow-up with neurology. She was referred for retinal evaluation due to a fundoscopic finding.

Photographer: Mauricio Bayram-Suverza. Fundación Hospital Nuestra Señora de la Luz. Mexico City.

Imaging device: TRC-50DX

Condition/keywords: tortuous vessels, vascular anomaly

Aug 20 2026 by Mauricio Bayram-Suverza, MD

Fluorescein angiography demonstrated late staining of the white dots.

Photographer: Mauricio Bayram-Suverza, Fundación Hospital Nuestra Señlora de la Luz. Mexico City

Imaging device: Optos California

Condition/keywords: multiple evanescent white dot syndrome (MEWDS)

Aug 20 2026 by Mauricio Bayram-Suverza, MD

Optical coherence tomography (OCT) showed selective disorganization of the outer retinal layers

Photographer: Mauricio Bayram-Suverza, Fundación Hospital Nuestra Señlora de la Luz. Mexico City

Imaging device: Spectralis

Condition/keywords: multiple evanescent white dot syndrome (MEWDS)

Aug 20 2026 by Mauricio Bayram-Suverza, MD

Fundus autofluorescence (FAF) revealed hyperautofluorescent lesions.

Photographer: Mauricio Bayram-Suverza, Fundación Hospital Nuestra Señlora de la Luz. Mexico City

Imaging device: Spectralis, blue Fundus autofluorescence

Condition/keywords: multiple evanescent white dot syndrome (MEWDS)

Aug 20 2026 by Mauricio Bayram-Suverza, MD

A 23 year-old female presented for evaluation after one week of blurred vision in the right eye. Her history was notable for a flu-like illness (viral prodrome) approximately one week before symptom onset. Fundus examination revealed the classic foveal granularity characteristic of multiple evanescent white dot syndrome (MEWDS), along with the remaining findings typical of this condition.

Photographer: Mauricio Bayram Suverza, Fundación Hospital Nuestra Señora de la Luz. Mexico City,

Imaging device: TRC-50DX

Condition/keywords: multiple evanescent white dot syndrome (MEWDS), white dot syndrome