Aug 20 2026 by JEFFERSON R SOUSA, Tecgº Biomedical Syst, Pg. in Visual Neuroscience

A 13-year-old male patient undergoing oncologic treatment presents with no light perception (NLP). Ophthalmologic examination revealed significant funduscopic abnormalities. Fundus photography of both eyes, presented as panoramic retinal montages, demonstrates extensive areas of arteriovascular compromise, as well as retinal hemorrhages and severe optic disc pallor.

Photographer: JEFFERSON R SOUSA - Departamento de Oftalmologia da (Lens Oftalmologia Hospital Beneficência Portuguesa), São Paulo-Brazil

Imaging device: Topcon TRC-50 DX, Imaginet 5.0, 50-degree angle. 50 W-s flash, panoramic retinal imaging with 14 images.

Condition/keywords: Acute myeloid leukaemia with Roth spots and leukaemia infiltrates, Leukemic optic neuropathy

Aug 18 2026 by Pablo Angel García-Uribe, MD, PhD

An 83 year-old man with bilateral pseudophakia and secondary glaucoma presented with a 2-year history of progressive, fluctuating visual loss, predominantly in the right eye. Wide-field fundus photography demonstrated dense whitish fibrillar, branching, and sheet-like vitreous opacities with a characteristic glass-wool appearance, markedly obscuring the posterior pole. Similar vitreous deposits were present in the fellow eye. The patient underwent pars plana vitrectomy and vitreous biopsy of the right eye. Intraoperatively, dense peripheral whitish vitreous bands were observed; after their removal, the retina was completely attached without evidence of vasculitis. Histopathologic examination demonstrated Congo red-positive material with characteristic birefringence under polarized light, confirming amyloid deposition.

Photographer: David García-García, Optometrist, Clínica Oftalmológica Salauno, Mexico City

Imaging device: VISUCAM 524(Carl Zeiss Meditec AG, Jena, Germany)

Condition/keywords: amyloidosis, vitreous amyloidosis

Aug 15 2026 by Anju Bansal

NVE's on angiography

Photographer: Dr. Anju Bansal

Condition/keywords: FFA, PRP

Aug 15 2026 by Siri Uppuluri

External photograph of a 66 year-old woman with migration of Ozurdex implant into anterior chamber.

Photographer: Siri Uppuluri, MD; Rutgers New Jersey Medical School

Condition/keywords: Ozurdex implant

Jun 19 2026 by César Adrián Gómez Valdivia, MD

Ultra-widefield fundus photograph showing hypotony maculopathy, characterized by prominent chorioretinal folds radiating through the posterior pole, vascular tortuosity, and a distorted macular contour. The image highlights the characteristic undulating retinal appearance associated with low intraocular pressure.

Photographer: César Adrián Gómez Valdivia

Imaging device: OPTOS

Condition/keywords: hypotony maculopathy

Jun 10 2026 by KANWALJEET HARJOT MADAN, M.S. (Ophthalmology); FAICO (Vitreous - Retina)

This is the fundus image of right eye of 65 years old male depicting Subretinal PFCL Bubbles with attached Retina. He had been operated for Retinal Detachment with Proliferative Vitreo-retinopathy previously.

Photographer: Dr. Kanwaljeet Harjot Madan, Jalandhar City (Punjab). INDIA.

Imaging device: Zeiss Fundus Camera

Condition/keywords: Proliferative Vitreoretinopathy, Retina detachment, Subretinal PFCL

Jun 23 2026 by SHRADDHA RAJ SHRIVASTAVA

Right eye G-FAF image of Stargardt Macular Dystrophy, showing hypoautofluorescence corresponding to central macular atrophy and variable hypo-hyperFAF corresponding to the pisciform flecks.

Photographer: Dr. Shraddha Raj Shrivastava

Imaging device: Nidek Mirante SLO/OCT (Confocal scanning/Spectral domain OCT)

Condition/keywords: fundus autofluorescence (FAF), fundus flavimaculatus, pisciform flecks, Stargardt Disease

Jul 28 2026 by rohan jain

A case of a 74 year-old male who presented with 1 month of decreased vision in OD (hand movement), with 03 IOP, was given posterior subtenon's injection of triamcilonone along with steroid eye drops.

Photographer: Dr. ROHAN JAIN

Imaging device: mirante

Condition/keywords: choroidal detachment

Jul 23 2026 by Pablo Angel García-Uribe, MD, PhD

A 61-year-old woman with a history of systemic hypertension treated with nifedipine and aspirin 100 mg daily underwent combined phacoemulsification and pars plana vitrectomy in the right eye for cataract and dense vitreous hemorrhage of initially undetermined etiology. This macula-centered color fundus photograph demonstrates a large submacular fibrovascular scar associated with extensive retinal pigment epithelium alterations and multiple areas of subretinal hemorrhage in different stages of evolution. Both chronic and more recent hemorrhagic components are visible within and surrounding the macular region. The clinical appearance was highly suggestive of presumed polypoidal choroidal vasculopathy complicated by recurrent subretinal bleeding and advanced submacular fibrosis.

Photographer: David García-García, Optometrist, Clínica Oftalmológica Salauno, Mexico City

Imaging device: Fundus camera VISUCAM 524(Carl Zeiss Meditec AG, Jena, Germany)

Condition/keywords: fibrosis, idiopathic polypoidal choroidal vasculopathy, partially reabsorbed subretinal hemorrhage, polypoidal choroidal vasculopathy (PCV), subretinal, subretinal hemorrhage, subretinal blood

Jul 22 2026 by Gabriel Costa Andrade, PhD

A 56 year-old patient with a history of rhegmatogenous retinal detachment in the right eye underwent retinal reattachment surgery, including scleral buckling, pars plana vitrectomy, endolaser photocoagulation, and partial silicone oil tamponade. During the postoperative follow-up, recurrent inferior retinal detachment associated with proliferative vitreoretinopathy (PVR) was identified.

Photographer: Gabriel Andrade

Condition/keywords: detached retina, retina, Retina detachment, vitrectomy

Jun 24 2026 by Elysse Tom, MD

Fundus photograph of a 33 year-old female with a giant retinal tear and retinal detachment after bungee cord injury to her right eye.

Condition/keywords: giant retinal tear, GRT

Jul 21 2026 by Shikhara Vijayan

Fundus photo of a 10 year-old boy shows a thick Falciform fold from the optic disc to peripheral granuloma of Toxocara granuloma.

Condition/keywords: ultra-wide field imaging

May 5 2026 by César Adrián Gómez Valdivia, MD

Heidelberg fundus autofluorescence image demonstrating bull’s-eye maculopathy. The macula shows a characteristic parafoveal ring of abnormal autofluorescence surrounding the foveal center, corresponding to retinal pigment epithelium and outer retinal dysfunction. Areas of decreased autofluorescence represent RPE atrophy, while adjacent increased autofluorescence highlights stressed or metabolically altered RPE. The pattern is well demarcated and symmetric, consistent with a classic bull’s-eye configuration.

Photographer: César Adrián Gómez-Valdivia

Condition/keywords: bulls eye maculopathy, hydroxychloroquine toxicity

Apr 28 2026 by Rebecca Hong

A 60 year-old man with poorly controlled JAK2+ polycythaemia vera (PV) on hydroxyurea presented with progressive bilateral vision loss. Fundoscopy revealed bilateral choroidal neovascular membranes (CNVM) with subtle radial streaks emanating from the optic discs (A). Fundus autofluorescence (B) elegantly demonstrated the angioid streaks with striking perilesional hyperautofluorescence - a hallmark of RPE metabolic stress. On optical coherence tomography, the right eye showed active neovascularisation with intra- & subretinal fluid, responding favourably to intravitreal anti-VEGF therapy. The left eye exhibited atrophic changes precluding treatment. This case underscores a rare but sight-threatening complication of PV.

Photographer: Rebecca Hong, MD MPHTM

Imaging device: Optos Ultra-widefield

Condition/keywords: Angioid Streaks, choroidal neovascular membrane (CNVM), polycythaemia vera

May 6 2026 by Sakthi Gnana Sundaram Natarajan, MS

An interesting case of a 60 year-old man, who is diagnosed to have Diabetic macular edema - being treated with Ozurdex implant. Here, we see the former implant, laying in the vitreous after serving its purpose, making way for the second newly injected implant to start its miracle - like a shadow lurking past - The Deja Vu of Life.

Photographer: DR.SUPREME GOEL , FELLOW - FNB VITREO RETINAL SURGERY , CHAITHANYA EYE HOSPITAL & RESEARCH INSTITUTE , THIRUVANANTHAPURAM , KERALA , INDIA.

Imaging device: OPTOS ultra-widefield (UWF™) retinal imaging

Condition/keywords: Corticosteroid implant, cystoid macular edema (CME), dexamethasone implant, diabetic macular oedema, intravitreal implant, intravitreal injection, ozurdex, Ozurdex implant

May 12 2026 by Hrishikesh Naik, MS

A fundus photograph of a 53 year-old with retinal detachment associated with a giant retinal tear.

Imaging device: Zeiss Visucam 224

Condition/keywords: giant retinal tear, retinal detachment

May 10 2026 by Greeshma M G

Widefield spectral-domain OCT demonstrates a taut posterior hyaloid, epiretinal membrane, and multiple fibrovascular tractional membranes, creating a striking architectural distortion in a case of advanced diabetic eye disease.

Photographer: Alfina M S

Condition/keywords: diabetic retinopathy

May 7 2026 by César Adrián Gómez Valdivia, MD

Follow-up color fundus photograph after intravitreal aflibercept and pneumatic displacement showing marked clearing/displacement of the premacular hemorrhage, with residual intraretinal hemorrhage along the temporal arcade and persistent circinate hard exudates involving the macular region. The retinal arterial macroaneurysm remains visible, with improved visualization of the posterior pole compared with the initial presentation.

Photographer: César Adrián Gómez-Valdivia

Imaging device: Topcon

Condition/keywords: ruptured macroaneurysm

May 20 2026 by Vinod Kumar, MS DNB MNAMS FRCS (Glasg)

Wide-Field OCT Angiography of a 50 year-old male with proliferative diabetic retinopathy.

Photographer: Kabirrudin Molla

Imaging device: Dream OCT

Condition/keywords: OCTA, PDR, ULTRA WIDE FIELD

May 21 2026 by Vishal Agrawal, MD, FRCS,FACS,FASRS

A 35 year-old male developed progressive profound vision loss following uncomplicated cataract surgery and subsequent intravitreal vancomycin/ceftazidime for suspected postoperative endophthalmitis. Fundus examination revealed circumferential midperipheral fibrosed retinal vasculitis / neovascularization with pericentral retinal ischemia and scattered hemorrhages. Fluorescein angiography demonstrated extensive capillary nonperfusion encircling the posterior pole and temporal macula with an enlarged irregular FAZ, consistent with hemorrhagic occlusive retinal vasculitis (HORV).

Photographer: Dr Ayushi Gupta, Agrawal Hospital, Jaipur

Imaging device: Clarus 700

Condition/keywords: HORV, retinal vasculitis, VANCOMYCIN