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Jul 10 2025 by Jessilla Phou

These are fundus photographs capturing an 18 year old male with Type 1 Sialidosis, a rare inherited lysosomal storage disorder caused by a deficiency in the neuraminidase 1 (Neu1) enzyme. Currently, there are fewer than 1,000 people in the USA who have this disorder. It is characterized by a cherry red spot in the macula which occurs when lipids accumulate in the retinal ganglion cells. This causes the macula to appear red as seen in these fundus images. The patient presented at our office with ataxia, depth perception issues, and slow reaction time. His visual acuity was 20/40, suggestive of early stage Sialidosis.

Photographer: Jessilla Phou

Imaging device: Optos California

Condition/keywords: cherry red spot, fundus photograph, Sialidosis

Jul 9 2025 by Majda Hadziahmetovic, MD

Fluorescein angiography image demonstrating multiple areas of neovascularization in a middle-aged male patient with long-standing diabetes.

Condition/keywords: proliferative diabetic retinopathy (PDR)

Jul 9 2025 by Jeffrey Barker

57 year old male presents with Proliferative Diabetic Retinopathy and Tractional Retina detachment.

Photographer: Jeffrey P. Barker, B.S. Retina Vitreous Surgeons of CNY

Condition/keywords: Diabetes, proliferative diabetic retinopathy (PDR), Traction retinal detachment

Jul 9 2025 by Hrishikesh Naik, MS

A peripapillary colobomatous pseudo-duplication of the optic disc as seen in an asymptomatic 23 year old female with myopia referred for routine retinal periphery screening. Rest retinal exam was normal. Duplication of the optic disc can be classified as either true duplication or pseudoduplication, both of which are rare clinical conditions. Pseudodoubling of the optic disc is commonly caused by optic disc or peripapillary colobomas, characterized by a circumscribed, disc-like lesion with radiating vessels but only one normal optic nerve. A few cases have involved pathological myopia, moderate myopia, proliferative diabetic retinopathy and CHARGE syndrome. The lesion is often found inferior to the normal optic disc. The patient was advised regular follow ups.

Photographer: Hrishikesh Naik

Imaging device: Optos Daytona

Condition/keywords: Coloboma, Pseudoduplication of optic disc

Jul 8 2025 by Niloofar Piri, MD

Mid AV phase fluorescein angiogram of a 13 yo AA male with SC disease demonstrating multiple classic sea fan neovascularization with peripheral capillary non perfusion (CNP). CNP is more obvious in this image involving the temporal retina and inferonasal retina.

Photographer: Stefan Raev, COT, Saint Louis University

Condition/keywords: Proliferative sickle cell retinopathy, proliferative sickle retinopathy, sickle cell retinopathy

Jul 8 2025 by T. P . VIGNESH, MBBS,MS

Fundus photograph of an 45 year old man revealing CSCR with subretinal precipitates.

Photographer: Sivanath

Imaging device: EIDON

Condition/keywords: central serous chorioretinopathy (CSCR)

Jul 7 2025 by Jenn Geelan

FA photo of a 34 year old male with prior stage 3 ROP with history of 360 degree cryotherapy.

Photographer: Jenn Geelan, Retina-Vitreous Surgeons of CNY

Imaging device: Optos California

Condition/keywords: cryotheraphy scar, fluorescein angiogram (FA), fundus photograph, retinopathy of prematurity (ROP), ROP, tilted disc

Jul 7 2025 by Moazzam Parvez

Fundus fluorescein image of a 62 year old gentleman in the early phase showing diffuse RPE mottling in the temporal aspect of the arcade.

Photographer: Moazzam Parvez

Imaging device: Heidelberg Spectralis

Condition/keywords: FA early phase, FFA, RPE mottling

Jul 7 2025 by César Adrián Gómez Valdivia, MD

Scimitar Sign & Sunset Glow Fundus found in a 38YO female patient diagnosed with Vogt-Koyanagi-Harada disease. Findings were bilateral.

Photographer: @eyemissu2

Imaging device: TOPCON TRC-50DX

Condition/keywords: Scimitar Sign

Jul 7 2025 by César Adrián Gómez Valdivia, MD

Neuroretinitis found in a 38 YO male patient with IV drugs abuse history. Findings were bilateral. The lipid-rich component of the exudate is able to penetrate into the outer plexiform layer, creating what is clinically seen as a macular star pattern.

Photographer: @eyemissu2

Imaging device: TOPCON TRC-50DX

Condition/keywords: neuroretinitis

Jul 7 2025 by César Adrián Gómez Valdivia, MD

Fluorescein Angiography showing a Schlaegel Line in a patient with suspected PHOS

Photographer: @eyemissu2

Imaging device: California ICG OPTOS

Condition/keywords: Schlaegel Line

Jul 5 2025 by Gustavo Uriel Fonseca Aguirre

This B-mode transverse ultrasound scan reveals a mushroom-shaped choroidal tumor in the inferior nasal quadrant adjacent to the optic nerve head. The lesion appears solid with homogeneous internal reflectivity and is associated with minimal surrounding subretinal fluid and scleral excavation. It measures 6.54 mm in height × 7.52 mm in base diameter (transverse view) and extends 9.52 mm longitudinally. The vitreous contains abundant punctate opacities consistent with pigment dispersion. The retina and choroid remain attached elsewhere.

Photographer: Gustavo U. Fonseca Aguirre, Hospital Conde de Valenciana, Ciudad de México

Condition/keywords: choroidal melanoma

Jul 5 2025 by Gustavo Uriel Fonseca Aguirre

This wide-field fundus autofluorescence image demonstrates a mushroom-shaped choroidal melanoma adjacent to the optic nerve head, exhibiting hypo-autofluorescence (melanin). Vitreous pigment dispersion (tobacco dust sign) is evident, indicating tumor activity.

Photographer: Gustavo U. Fonseca Aguirre, Hospital Conde de Valenciana, Ciudad de México

Condition/keywords: choroidal melanoma

Jul 5 2025 by Gustavo Uriel Fonseca Aguirre

This B-mode longitudinal ultrasound scan reveals a giant retinal tear, demonstrating a circumferential retinal flap with rolled edges extending over M-X to M-I. The vitreous shows diffuse hemorrhage and anterior-posterior traction strands inserting at the tear margins. The remaining retina appears attached without subretinal fluid.

Photographer: Gustavo U. Fonseca Aguirre, Hospital Conde de Valenciana, Ciudad de México

Condition/keywords: giant retinal tear

Jul 5 2025 by Gustavo Uriel Fonseca Aguirre

This 50° central fundus photograph reveals a mushroom-shaped choroidal melanoma adjacent to the optic nerve head. The lesion demonstrates characteristic pigmentation with overlying vitreous pigment dispersion (tobacco dust sign).

Photographer: Gustavo U. Fonseca Aguirre, Hospital Conde de Valenciana, Ciudad de México

Condition/keywords: choroidal melanoma

Jul 5 2025 by Gustavo Uriel Fonseca Aguirre

This B-mode longitudinal ultrasound scan demonstrates a retinal dialysis, appearing as a linear discontinuity at the ora serrata with associated vitreous base avulsion. The scan reveals mild subretinal fluid extending from the dialysis site with macular involvement.

Photographer: Gustavo U. Fonseca Aguirre, Hospital Conde de Valenciana, Ciudad de México

Condition/keywords: retinal dialysis

Jul 5 2025 by César Adrián Gómez Valdivia, MD

Giant Persistent Macular Hole found in a 48YO male patient 1 year after vitrectomy.

Photographer: @eyemissu2

Imaging device: TOPCON TRC-50DX

Condition/keywords: macular hole

Jul 5 2025 by César Adrián Gómez Valdivia, MD

Fundus photograph of an 66 YO female patient diagnosed with advanced proliferative diabetic retinopathy.

Photographer: @eyemissu2

Imaging device: TOPCON TRC-50DX

Condition/keywords: tractional retinal detachment

Jul 5 2025 by T. P . VIGNESH, MBBS,MS

Fundus photograph of a 52-year-old man with a macular branch retinal vein occlusion and macular edema.

Photographer: Sivanath

Imaging device: EIDON

Condition/keywords: branch retinal vein occlusion (BRVO)

Jul 4 2025 by Julian Navarro Saucedo

Fundus photograph of a 52-year-old woman with sudden vision loss showing a hemorrhagic retinal arterial macroaneurysm.

Photographer: Julian Navarro, Tecnologico de Monterrey, Escuela de Medician y Ciencias de la Salud.

Imaging device: VISUCAM 524 ZEISS

Condition/keywords: macroaneurysm