Human Vitreous Collagen Fibril

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File number: 62206


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    Appears in
    Vitreous
    Condition/keywords
    vitreous, collagen, vitreous fibrils
    Description
    Schematic diagram of human vitreous collagen fibril showing the central core of hybrid types V/XI surrounded by type II collagen, the most prevalent type in both vitreous and joints. Type IX is located on the surface of the fibril where it can mediate interactions with other extracellular matrix components in the vitreous body. [From Bishop PN: The biochemical structure of mammalian vitreous. Eye 1996;10:664–70; reprinted in Sebag J: Vitreous – in Health & Disease. Springer, New York, 2014; image © Springer Nature, reprinted with permission]

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