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By McGill University Health Centre
The MUHC-McGill University
Co-author(s): Sabrina Bergeron, P. Zoroquiain, E. Esposito, S. Corredor Casas, P. Logan, A. N. Odashiro, Miguel N. Burnier, Paulina García de Alba Graue, McGill University Health Center-McGill University Ocular Pathology & Translational Research Laboratory - Uploaded on May 18, 2020.
- Last modified by Caroline Bozell on May 19, 2020.
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- Appears in
- Infiltration of the Optic Nerve
- Condition/keywords
- infiltration of the optic nerve
- Description
- The main morphological prognostic factor for retinoblastoma is infiltration of the optic nerve. The invasion of the optic nerve has to be assessed by a pathologist in all cases. The superior calotte is removed in this enucleation specimen to show an extensively exophytic necrotic tumor occupying the vitreous chamber with severe infiltration of the optic nerve (arrowhead). Intratumoral calcification is a hallmark of this tumor and can be seen in the chalky white areas (arrow).
