McGill University Health Centre » Infiltration of the Optic Nerve

May 18 2020 by McGill University Health Centre

The main morphological prognostic factor for retinoblastoma is infiltration of the optic nerve. The invasion of the optic nerve has to be assessed by a pathologist in all cases. The superior calotte is removed in this enucleation specimen to show an extensively exophytic necrotic tumor occupying the vitreous chamber with severe infiltration of the optic nerve (arrowhead). Intratumoral calcification is a hallmark of this tumor and can be seen in the chalky white areas (arrow).

Condition/keywords: infiltration of the optic nerve