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By César Adrián Gómez Valdivia, MD
Fundación Hospital Nuestra Señora de la Luz, I.A.P.
Co-author(s): Dr. Mauricio Bayram-Suverza - Uploaded on May 5, 2026.
- Last modified by Joshua Friedman on May 6, 2026.
- Rating
- Appears in
- Bulls Eye Maculopathy
- Condition/keywords
- bullseye maculopathy, hydroxychloroquine toxicity
- Photographer
- César Adrián Gómez-Valdivia
- Imaging device
- Fundus camera
- Description
- CLARUS blue fundus autofluorescence image demonstrating bull’s-eye maculopathy. The posterior pole shows a well-defined parafoveal ring of abnormal autofluorescence surrounding a relatively preserved foveal center, producing the classic bull’s-eye pattern. Hypoautofluorescent areas correspond to retinal pigment epithelium atrophy or loss, while adjacent hyperautofluorescence reflects stressed or dysfunctional RPE. The macular changes are symmetric and sharply demarcated, consistent with outer retinal and RPE degeneration.
