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By Robert Andrew Sisk, MD, FACS, FASRS
Cincinnati Eye Institute - Uploaded on Mar 25, 2025.
- Last modified by Joshua Friedman on Mar 26, 2025.
- Rating
- Appears in
- Miscellaneous
- Condition/keywords
- Gene Therapy, Subretinal Injection, Fluid-Air Exchange, genetic disorder
- Imaging device
- Leica Proveo 8
- Description
- Color stills from surgical video after subretinal delivery of gene augmentation therapy with voretigene neparvovec-rzyl A) before and B) after fluid-air exchange (FAX). The blebs were between 0.5- and 1-disc diameters from the fovea. After FAX, they gradually extended beneath the fovea and eventually merged. This spared the fovea the trauma from the injection pressure of subretinal injection while allowing treatment to the area.
