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By Robert Andrew Sisk, MD, FACS, FASRS
Cincinnati Eye Institute - Uploaded on Mar 25, 2025.
- Last modified by Joshua Friedman on Mar 26, 2025.
- Rating
- Appears in
- Miscellaneous
- Condition/keywords
- gene therapy, genetic disorder, subretinal injection, optical coherence tomography (OCT), retinitis pigmentosa
- Imaging device
- Zeiss Artevo 800
- Description
- Color still from surgical video of subretinal delivery of laru-zova for X-linked retinitis pigmentosa. Live optical coherence tomography (OCT) with foveal tracking via the embedded software in the operating microscope allows monitoring foveal integrity for signs of stress. The contour of the fovea does not exceed the curvature of the bleb (e.g. no inversion). The tangential cannula angle facilitated steering of the bleb posteriorly. The bleb covers essentially the entire macula, which is the target area.
