Search results (8 results)

Dec 10 2020 by McGill University Health Centre

47-year-old female with cough and fever. Imaging showed a right pulmonary infiltrate. Transbronchial needle biopsy revealed lymphangitic spread of papillary adenocarcinoma with psammoma bodies. MRI of thyroid, CT of abdomen and pelvis were negative. gynecologic evaluation negative at that time. The patient had bilateral floaters, VA: 20/40 OD and 20/20 OS. Fundus examination showed retinal arteriolar sheathing and a flat choroidal lesion OS and vitritis OD. Fluorescein angiogram showed staining of left superior temporal retinal arterioles and bilateral midperipheral patchy hyperfluorescence at RPE The patient vision in the OD deteriorated to 20/400, and in the OS 20/50. Four months later a new choroidal lesion was diagnosed OS. An abdominal mass consistent with a cystadenoma of the ovary was diagnosed. After a year patient developed systemic metastasis. Autopsy: Metastatic adenocarcinoma to the lung, both adrenals, para-aortic lymph nodes, left hip, right breast, occipital skin, serosal surface of liver, pituitary. In almost all metastatic lesions psammoma bodies were found. Presumptive diagnosis is a primary tumor of the ovary.

Condition/keywords: bilateral, calcification, metastatic adenocarcinoma, retinal arteriolar occlusion

May 18 2020 by McGill University Health Centre

Metastatic disease is the most frequent intraocular malignant tumor. In women, the most common origin is breast cancer. In men, the most common origin is lung cancer. This pupil–optic nerve section shows a whitish tumor with several foci of necrosis (*) occupying the posterior aspect of the choroid. Note the pigment epithelium over the inner surface of the tumor. A serous retinal detachment is present (arrow) with a retinal detachment artifact overlying the tumor and normal choroid. Note the air bubble artifacts in the vitreous cavity. Another artifact, the compression of the eyeball, is present on the right side.

Condition/keywords: breast cancer, foci of necrosis, metastatic adenocarcinoma, tumor

Dec 10 2020 by McGill University Health Centre

47-year-old female with cough and fever. Imaging showed a right pulmonary infiltrate. Transbronchial needle biopsy revealed lymphangitic spread of papillary adenocarcinoma with psammoma bodies (MRI of thyroid, CT of abdomen and pelvis were negative) gynecologic evaluation negative at that time. The patient had bilateral floaters, VA: 20/40 OD and 20/20 OS. Fundus examination showed retinal arteriolar sheathing and a flat choroidal lesion OS and vitritis OD. Fluorescein angiogram showed staining of left superior temporal retinal arterioles and bilateral midperipheral patchy hyperfluorescence at RPE. The patient vision in the OD deteriorated to 20/400, and in the OS 20/50. Four months later a new choroidal lesion was diagnosed OS. An abdominal mass consistent with a cystadenoma of the ovary was diagnosed. After a year patient developed systemic metastasis. Autopsy: Metastatic adenocarcinoma to the lung, both adrenals, para-aortic lymph nodes, left hip, right breast, occipital skin, serosal surface of liver, pituitary. In almost all metastatic lesions psammoma bodies were found. Presumptive diagnosis is a primary tumor of the ovary.

Imaging device: Fluoroscein angiogram

Condition/keywords: bilateral, calcification, metastatic adenocarcinoma, retinal arteriolar occlusion

Dec 10 2020 by McGill University Health Centre

47-year-old female with cough and fever. Imaging showed a right pulmonary infiltrate. Transbronchial needle biopsy revealed lymphangitic spread of papillary adenocarcinoma with psammoma bodies (MRI of thyroid, CT of abdomen and pelvis were negative) gynecologic evaluation negative at that time. The patient had bilateral floaters, VA: 20/40 OD and 20/20 OS. Fundus examination showed retinal arteriolar sheathing and a flat choroidal lesion OS and vitritis OD. Fluorescein angiogram showed staining of left superior temporal retinal arterioles and bilateral midperipheral patchy hyperfluorescence at RPE. The patient vision in the OD deteriorated to 20/400, and in the OS 20/50. Four months later a new choroidal lesion was diagnosed OS. An abdominal mass consistent with a cystadenoma of the ovary was diagnosed. After a year patient developed systemic metastasis. Autopsy: Metastatic adenocarcinoma to the lung, both adrenals, para-aortic lymph nodes, left hip, right breast, occipital skin, serosal surface of liver, pituitary. In almost all metastatic lesions psammoma bodies were found. Presumptive diagnosis is a primary tumor of the ovary. Histopathologic examination of both eyes disclosed : Bilateral metastatic adenocarcinoma to the vitreous with partially calcified proliferation along internal limiting membrane, OS. Metastatic adenocarcinoma to choroid, OS. Bilateral optic atrophy secondary to retinal arteriolar occlusion with calcification.

Condition/keywords: bilateral, calcification, histopathology, metastatic adenocarcinoma, pathology, retinal arteriolar occlusion

Dec 10 2020 by McGill University Health Centre

47-year-old female with cough and fever. Imaging showed a right pulmonary infiltrate. Transbronchial needle biopsy revealed lymphangitic spread of papillary adenocarcinoma with psammoma bodies (MRI of thyroid, CT of abdomen and pelvis were negative) gynecologic evaluation negative at that timePatient had bilateral floaters, VA: 20/40 OD and 20/20 OS. Fundus examination showed retinal arteriolar sheathing and a flat choroidal lesion OS and vitritis OD. Fluorescein angiogram showed staining of left superior temporal retinal arterioles and bilateral midperipheral patchy hyperfluorescence at RPE The patient vision in the OD deteriorated to 20/400, and in the OS 20/50. Four months later a new choroidal lesion was diagnosed OS. An abdominal mass consistent with a cystadenoma of the ovary was diagnosed. After a year patient developed systemic metastasis. Autopsy: Metastatic adenocarcinoma to the lung, both adrenals, para-aortic lymph nodes, left hip, right breast, occipital skin, serosal surface of liver, pituitary. In almost all metastatic lesions psammoma bodies were found. Presumptive diagnosis is a primary tumor of the ovary. Histopathologic examination of both eyes disclosed : Bilateral metastatic adenocarcinoma to the vitreous with partially calcified proliferation along internal limiting membrane, OS. Metastatic adenocarcinoma to choroid, OS. Bilateral optic atrophy secondary to retinal arteriolar occlusion with calcification.

Condition/keywords: bilateral, calcification, histopathology, metastatic adenocarcinoma, pathology, retinal arteriolar occlusion

Dec 10 2020 by McGill University Health Centre

47-year-old female with cough and fever. Imaging showed a right pulmonary infiltrate. Transbronchial needle biopsy revealed lymphangitic spread of papillary adenocarcinoma with psammoma bodies (MRI of thyroid, CT of abdomen and pelvis were negative) gynecologic evaluation negative at that time. The patient had bilateral floaters, VA: 20/40 OD and 20/20 OS. Fundus examination showed retinal arteriolar sheathing and a flat choroidal lesion OS and vitritis OD. Fluorescein angiogram showed staining of left superior temporal retinal arterioles and bilateral midperipheral patchy hyperfluorescence at RPE. The patient vision in the OD deteriorated to 20/400, and in the OS 20/50. Four months later a new choroidal lesion was diagnosed OS. An abdominal mass consistent with a cystadenoma of the ovary was diagnosed. After a year patient developed systemic metastasis. Autopsy: Metastatic adenocarcinoma to the lung, both adrenals, para-aortic lymph nodes, left hip, right breast, occipital skin, serosal surface of liver, pituitary. In almost all metastatic lesions psammoma bodies were found. Presumptive diagnosis is a primary tumor of the ovary. Histopathologic examination of both eyes disclosed : Bilateral metastatic adenocarcinoma to the vitreous with partially calcified proliferation along internal limiting membrane, OS. Metastatic adenocarcinoma to choroid, OS. Bilateral optic atrophy secondary to retinal arteriolar occlusion with calcification.

Condition/keywords: bilateral, calcification, histopathology, metastatic adenocarcinoma, pathology, retinal arteriolar occlusion

Dec 10 2020 by McGill University Health Centre

47-year-old female with cough and fever. Imaging showed a right pulmonary infiltrate. Transbronchial needle biopsy revealed lymphangitic spread of papillary adenocarcinoma with psammoma bodies (MRI of thyroid, CT of abdomen and pelvis were negative) gynecologic evaluation negative at that time. The patient had bilateral floaters, VA: 20/40 OD and 20/20 OS. Fundus examination showed retinal arteriolar sheathing and a flat choroidal lesion OS and vitritis OD. Fluorescein angiogram showed staining of left superior temporal retinal arterioles and bilateral midperipheral patchy hyperfluorescence at RPE The patient vision in the OD deteriorated to 20/400, and in the OS 20/50. Four months later a new choroidal lesion was diagnosed OS. An abdominal mass consistent with a cystadenoma of the ovary was diagnosed. After a year patient developed systemic metastasis. Autopsy: Metastatic adenocarcinoma to the lung, both adrenals, para-aortic lymph nodes, left hip, right breast, occipital skin, serosal surface of liver, pituitary. In almost all metastatic lesions psammoma bodies were found. Presumptive diagnosis is a primary tumor of the ovary. Histopathologic examination of both eyes disclosed : Bilateral metastatic adenocarcinoma to the vitreous with partially calcified proliferation along internal limiting membrane, OS. Metastatic adenocarcinoma to choroid, OS. Bilateral optic atrophy secondary to retinal arteriolar occlusion with calcification.

Condition/keywords: bilateral, calcification, histopathology, metastatic adenocarcinoma, pathology, retinal arteriolar occlusion

Dec 10 2020 by McGill University Health Centre

47-year-old female with cough and fever. Imaging showed a right pulmonary infiltrate. Transbronchial needle biopsy revealed lymphangitic spread of papillary adenocarcinoma with psammoma bodies (MRI of thyroid, CT of abdomen and pelvis were negative) gynecologic evaluation negative at that time. The patient had bilateral floaters, VA: 20/40 OD and 20/20 OS. Fundus examination showed retinal arteriolar sheathing and a flat choroidal lesion OS and vitritis OD. Fluorescein angiogram showed staining of left superior temporal retinal arterioles and bilateral midperipheral patchy hyperfluorescence at RPE The patient vision in the OD deteriorated to 20/400, and in the OS 20/50. Four months later a new choroidal lesion was diagnosed OS. An abdominal mass consistent with a cystadenoma of the ovary was diagnosed. After a year patient developed systemic metastasis. Autopsy: Metastatic adenocarcinoma to the lung, both adrenals, para-aortic lymph nodes, left hip, right breast, occipital skin, serosal surface of liver, pituitary. In almost all metastatic lesions psammoma bodies were found. Presumptive diagnosis is a primary tumor of the ovary. Histopathologic examination of both eyes disclosed : Bilateral metastatic adenocarcinoma to the vitreous with partially calcified proliferation along internal limiting membrane, OS. Metastatic adenocarcinoma to choroid, OS. Bilateral optic atrophy secondary to retinal arteriolar occlusion with calcification.

Condition/keywords: bilateral, calcification, histopathology, metastatic adenocarcinoma, pathology, retinal arteriolar occlusion