Search results (117 results)

Feb 17 2017 by Kristen Wagner

22-year-old female fundus photograph of a right eye with Optic Nerve Drusen with Idiopathic CNV.

Photographer: Kristen Wagner, COT, OSC Ophthalmic Photographer, Tennessee Retina, Nashville TN

Condition/keywords: choroidal neovascularization (CNV), drusen of optic disc, optic disc drusen

Apr 21 2025 by Virginia Gebhart

28 year old male with stable retinitis pigmentosa and optic disc drusen OU. Bardet-Biedl variant identified in previous genetic testing. BCVA 20/50 OD, 20/30 OS

Photographer: Virginia Gebhart, Retina Consultants of Carolina

Imaging device: Optos California

Condition/keywords: Drusen, optic disc drusen, retinitis pigmentosa

Apr 18 2025 by DR Rohit Gupta

The **myelinated nerve fibers of the optic disc** (also known as **medullated nerve fibers**) are retinal nerve fibers that retain their myelin sheath as they pass through the optic nerve head. Normally, retinal nerve fibers are unmyelinated to allow for light transparency, but in some cases, myelination extends anteriorly into the retina, appearing as a striking white, feathery patch on the optic disc or peripapillary retina. ### **Key Features:** 1. **Appearance:** - Dense, white, striated patches with feathery edges. - Typically located at the superior or inferior pole of the optic disc. - May obscure retinal vessels underneath. 2. **Clinical Significance:** - Usually **benign** and asymptomatic. - **Congenital** (present at birth or early childhood). - Rarely associated with **visual field defects** (e.g., scotomas corresponding to the area of myelination). - Occasionally linked with **high myopia** or **amblyopia** if extensive. 3. **Pathophysiology:** - Failure of oligodendrocytes or Schwann cells to stop myelination at the lamina cribrosa. - Normally, myelination stops at the optic nerve head, but in this condition, it extends into the retina. 4. **Diagnosis:** - **Fundoscopy:** Classic white, feathery appearance. - **Optical Coherence Tomography (OCT):** Shows thickened retinal nerve fiber layer (RNFL). - **Visual Field Testing:** May detect defects if large. 5. **Differential Diagnosis:** - Optic disc edema - Cotton wool spots - Retinoblastoma (rarely, but must be ruled out in children) 6. **Management:** - No treatment required if asymptomatic. - Monitor for amblyopia in children. - Rare cases with significant visual impairment may need further evaluation. ### **Fun Fact:** Myelinated nerve fibers are seen in **~0.5-1%** of the population and are usually an incidental finding.

Photographer: Dr Rohit gupta

Imaging device: Samsung S21

Condition/keywords: Medulated Nerve fibre, Medullated Nerve fibres, myelinated nerve fibers, Myelinated Nerve Fibres, optic disc drusen

Jun 29 2022 by Mohamed Awadalla, MD, FRCSEd

Autofluorescence in optic disc drusen Red free fundus photo

Condition/keywords: Autofluorescence, optic disc drusen

Jul 10 2013 by Hamid Ahmadieh, MD

Fundus autofluorescence image of the left eye of a 24-year-old woman with optic disc drusen and VA 20/20.

Photographer: Solmaz Shahmohammad, Negah Eye Center, Tehran

Imaging device: Heidelberg Spectralis

Condition/keywords: fundus autofluorescence (FAF), optic disc drusen

Dec 25 2012 by Alex P. Hunyor, MD

Autofluorescent image of the right optic disc showing autofluorescence of optic disc drusen.

Condition/keywords: optic disc drusen

Jun 3 2020 by Mirko Ratkovic, MD

Optic disc drusen and angioid streaks.

Condition/keywords: angioid streaks, drusen of optic disc, fundus autofluorescence (FAF), fundus photograph

Jun 3 2020 by Mirko Ratkovic, MD

Optic disc drusen and angioid streaks.

Condition/keywords: angioid streaks, fundus autofluorescence (FAF), fundus photograph, optic disc drusen

Jun 3 2020 by Mirko Ratkovic, MD

Optic disc drusen and angioid streaks.

Condition/keywords: angioid streaks, fundus autofluorescence (FAF), fundus photograph, optic disc drusen

Jun 3 2020 by Mirko Ratkovic, MD

Optic disc drusen and angioid streaks.

Condition/keywords: angioid streaks, fundus autofluorescence (FAF), optic disc drusen

Jul 16 2023 by Aditya S Kelkar, MS, FRCS, FASRS,FRCOphth

Fundus autofluorescence imaging of a 22-year-old male with optic disc drusen seen as hyperautofluorescent spot.

Photographer: Dr. Harsh Jain

Condition/keywords: Autofluorescence imaging of Optic Disc Drusen

Jan 6 2020 by Sarah Oelrich

Angioid streaks with associated disc drusen and CNV.

Photographer: Sarah Oelrich CRA COT OCT-C

Imaging device: Topcon, Heidelberg

Condition/keywords: angioid streaks, choroidal neovascular membrane (CNVM), disc drusen

Aug 1 2018 by Emily Cooper

Fundus autofluorescence photo of a 62-year-old man who presented for evaluation of choroidal folds and optic disc drusen. He is currently following up with neuro-ophthalmology and has suspected intracranial hypertension.

Photographer: Emily Cooper, Retina Specialists of Michigan

Condition/keywords: choroidal folds, drusen of optic disc

Sep 21 2018 by Sarah Oelrich

Angioid streaks with associated disc drusen and CNV.

Photographer: Sarah Oelrich CRA COT, Southeastern Retina Associates Knoxville Tn

Condition/keywords: angioid streaks, autofluorescence imaging, choroidal neovascularization (CNV), disc drusen, infrared image

Mar 27 2013 by Henry J. Kaplan, MD

Autofluorescence imaging shows heper AF on the optic nerve head specially superiorly due to drusen in the same patient #2.

Imaging device: Heidelberg spectralis

Condition/keywords: drusen of optic disc, optic disc drusen, optic nerve drusen

Sep 21 2012 by Suber S. Huang, MD, MBA, FASRS

Optic disc drusen demonstrating autofluorescence

Mar 26 2019 by Gary R. Cook, MD, FACS

Autofluorescent (AF) image of the left eye of a 60-year-old with bilateral optic disc drusen; VA= 20/15.

Imaging device: Topcon VT-50

Condition/keywords: drusen of optic disc, optic disc drusen

Oct 30 2024 by JULIAN VILLARREAL, MD

FAF showing angiod streaks , optic disc drusen, and macular atrophy secondary to macular neovascular membrane.

Photographer: Julián Villarreal MD

Imaging device: Mirante

Condition/keywords: Angioid Streaks, macular atrophy, optic disc drusen

Feb 19 2013 by From the Collections of Thomas M. Aaberg, MD and Thomas M. Aaberg Jr., MD

Unknown lesion, astrocytoma, exuberant disc drusen.

Condition/keywords: astrocytoma, disc drusen

Feb 19 2013 by From the Collections of Thomas M. Aaberg, MD and Thomas M. Aaberg Jr., MD

Unknown lesion, astrocytoma, exuberant disc drusen.

Condition/keywords: astrocytoma, disc drusen

Feb 19 2013 by From the Collections of Thomas M. Aaberg, MD and Thomas M. Aaberg Jr., MD

Unknown lesion, astrocytoma, exuberant disc drusen.

Condition/keywords: astrocytoma, disc drusen

May 28 2024 by Nishikant J Borse, MS, FMRF, FASRS

65-year-old female was referred for disc edema. An Autofluorescence Imaging was done which showed the autofluorescence of the optic nerve head drusen.

Photographer: Dr Nishikant Borse , Insight eye Clinic , Mumbai

Imaging device: Topcon Triton

Condition/keywords: Autofluorescence imaging of Optic Disc Drusen

May 28 2024 by Nishikant J Borse, MS, FMRF, FASRS

65-year-old female was referred for disc edema. An Autofluorescence Imaging was done which showed the autofluorescence of the optic nerve head drusen.

Photographer: Dr Nishikant Borse , Insight eye Clinic , Mumbai

Imaging device: Topcon Triton

Condition/keywords: Autofluorescence imaging of Optic Disc Drusen

Mar 2 2014 by Homayoun Tabandeh, MD, FASRS

Autofluorescence of optic disc drusen.

Condition/keywords: optic disc drusen

Dec 19 2012 by Eric A. Postel, MD

Buried optic disc drusen complicated by peripapillary subretinal neovascularisation

Condition/keywords: choroidal neovascularization (CNV), optic disc drusen