Search results (44 results)

Mar 9 2025 by Oscar Francisco Miranda, MD

A 36-year-old male with bilateral visual loss of 3 months' duration, with no relevant medical history on inquiry. A round-shaped lesion with well-defined borders and a yellowish-white color is observed in the macula of both eyes, accompanied by vitreous cellularity. The macular OCT shows a dentate RPE. The VDRL, FTA-ABS, and HIV tests were positive.

Photographer: Oscar Francisco Miranda-Gómez

Imaging device: Heidelberg Spectralis

Condition/keywords: acute syphilitic posterior placoid chorioretinitis, OCT, Ocular syphilis

Mar 9 2025 by Oscar Francisco Miranda, MD

A 36-year-old male with bilateral visual loss of 3 months' duration, with no relevant medical history on inquiry. A round-shaped lesion with well-defined borders and a yellowish-white color is observed in the macula of both eyes, accompanied by vitreous cellularity. The macular OCT shows a dentate RPE. The VDRL, FTA-ABS, and HIV tests were positive.

Photographer: Oscar Francisco Miranda-Gómez

Imaging device: Autofluorescence Zeiss Clarus 700

Condition/keywords: acute posterior placoid chorioretinitis, Autofluorescence, ocular syphilis

Mar 9 2025 by Oscar Francisco Miranda, MD

A 36-year-old male with bilateral visual loss of 3 months' duration, with no relevant medical history on inquiry. A round-shaped lesion with well-defined borders and a yellowish-white color is observed in the macula of both eyes, accompanied by vitreous cellularity. The macular OCT shows a dentate RPE. The VDRL, FTA-ABS, and HIV tests were positive.

Photographer: Oscar Francisco Miranda-Gómez

Imaging device: Zeiss Clarus 700

Condition/keywords: acute posterior placoid chorioretinitis, Ocular syphilis

Oct 20 2024 by César Adrián Gómez Valdivia, MD

Fundus autofluorescence image of an acute syphilitic posterior placoid chorioretinitis found in a HIV positive 28 YO male patient with suspected neurosyphilis. A beautiful butterfly autofluorescence pattern can be appreciated.

Photographer: @eyemissu2

Imaging device: California ICG OPTOS

Condition/keywords: acute syphilitic posterior placoid chorioretinitis

Oct 16 2024 by César Adrián Gómez Valdivia, MD

Fundus autofluorescence image of an acute syphilitic posterior placoid chorioretinitis found in a HIV positive 28 YO male patient with suspected neurosyphilis. A beautiful butterfly autofluorescence pattern can be appreciated.

Photographer: @eyemissu2

Imaging device: California ICG OPTOS

Condition/keywords: acute syphilitic posterior placoid chorioretinitis, chorioretinitis, syphilis

Mar 22 2024 by Anjana Mirajkar, MS Ophthalmology

An OCT image BE of 36 year old female showing RPE granularity and IS/OS irregularity in a case of syphilitic posterior placoid chorioretinitis

Photographer: Dr. Anjana Mirajkar -Retina Foundation, Ahmedabad

Condition/keywords: acute posterior placoid chorioretinitis, acute syphilitic posterior placoid chorioretinitis

Mar 22 2024 by Anjana Mirajkar, MS Ophthalmology

FA image of RE of a 36 year old female showing hyper-fluorescence (staining) from early to late phases of the angiogram in a case syphilitic posterior placoid chorioretinitis. ICG image depicts hypo-cyanence from early to late phases.

Photographer: Dr. Anjana Mirajkar -Retina Foundation, Ahmedabad

Imaging device: Heidelberg

Condition/keywords: acute syphilitic posterior placoid chorioretinitis

Mar 22 2024 by Anjana Mirajkar, MS Ophthalmology

FA image of LE of a 36 year old female showing hyper-fluorescence (staining) from early to late phases of the angiogram in a case syphilitic posterior placoid chorioretinitis. ICG image depicts hypo-cyanence from early to late phases.

Photographer: Dr. Anjana Mirajkar -Retina Foundation, Ahmedabad

Condition/keywords: acute syphilitic posterior placoid chorioretinitis

Mar 22 2024 by Anjana Mirajkar, MS Ophthalmology

A color photo image of RE of a 36 year old female showing hypopigmented lesions at the posterior pole(ground glass appearance) in a case of syphilitic posterior placoid chorioretinitis

Photographer: Dr. Anjana Mirajkar -Retina Foundation, Ahmedabad

Imaging device: Mirante-Nidek

Condition/keywords: posterior uveitis

Mar 22 2024 by Anjana Mirajkar, MS Ophthalmology

A color photo image of LE of a 36 year old female showing hypopigmented lesions at the posterior pole(ground glass appearance) in a case of syphilitic posterior placoid chorioretinitis

Photographer: Dr. Anjana Mirajkar -Retina Foundation, Ahmedabad

Imaging device: Mirante-Nidek

Condition/keywords: syphilitic posterior uveitis

Apr 24 2022 by Aniruddha K Agarwal, MD

Green-light fundus autofluorescence (FAF) of the right eye from a 55-year-old man with risk factors for sexually trasnmitted diseases who presented to the retina clinic for a central scotoma. Funduscopy revealed a placoid lesion in the posterior pole. FAF highlights a hyperautofluorescent placoid lesion involving the macula with granular hyperfluorescence. The patient tested positive for syphilis and received intravenous penicillin treatment.

Photographer: Esther CIANCAS, MD, PhD, Gema CRESPO-RODRÍGUEZ, RN

Imaging device: Zeiss Clarus fundus camera

Condition/keywords: chorioretinitis, IUSG, syphilis, uveitis

May 12 2021 by Joseph D Boss, MD

Ultra-widefield fundus photograph of a 36-year-old male with acute syphilitic posterior placoid chorioretinitis. Subsequent testing reviewed a positive RPR 1:256 and positive syphilis antibody.

Photographer: Joseph Boss, MD; Retina Specialists of Michigan

Condition/keywords: acute syphilitic posterior placoid chorioretinitis, syphilitis uveitis

May 4 2021 by RAFAEL REIS PEREIRA, MD

A 31-year-old patient with a complaint of photophobia and low visual acuity OD in the previous three weeks. BCVA was 20/60 and 20/20 The fundus examination revealed a placoid white lesion in the posterior pole and vitreous cells in the right eye. The left eye was unremarkable. Fluorescein angiography reveals hyperfluorescent plaque with distinctive “leopard spots” hypofluorescence.

Imaging device: Opto California

Condition/keywords: acute syphilitic posterior placoid chorioretinitis

Mar 30 2021 by Tanya Jain

A 41-year-old homosexual male patient presented with placoid chorioretinitis and was diagnosed with acute syphilitic posterior placoid chorioretinitis, neurosyphilis and HIV disease. The patient was started with HAART and intravenous antibiotics.

Photographer: Tanya Jain

Condition/keywords: acute syphilitic posterior placoid chorioretinitis, choroiditis, papillitis

Dec 20 2020 by John S. King, MD

44-year-old white female seen over the weekend complaining of a "spot" in her vision centrally OD for three days. She was referred over by another eye doctor who was concerned about a possible retinal detachment vs ARN in that eye. Her past medical history includes adrenal insufficiency for which she takes a low dose of hydrocortisone, thyroxine (post thyroidectomy), Plaquenil (inflammatory arthritis). She is divorced with one partner and denies any IVDU. Va 20/200 OD and 20/20 OS, IOP 12 OU, Pupils mydriatic post gtts (light desaturation OD). There was 1+ A/C cell OD, O/W unremarkable anterior segment OU; in the posterior segment OD there was 1+ vitritis with a diffusely swollen optic disc and a large yellowish placoid lesion in the macula with yellowish border and extended out past the arcades inferiorly, as well as another lesion smaller in the IN periphery. There was trace vitreous cell OS, mild disc edema, and a large, granular placoid area nasally that appeared to be granulated. The OCT showed mild subfoveal fluid with nodular areas in the RPE and some overlying irregular architecture of the outer retina. Syphilis was a concern at this point. She denied any hand or foot rash, and said that she was recently working on the house, and her hands were dried out. There did appear to be a rash on the hand (See Image), and later learned that she had a rash on the soles of her feet. She was sent to ED for a work-up and her syphilis IgG was positive and VDRL 1:128, and negative for HIV. She was started on a course IV Penicillin (40mg PO steroid two days after tx started). She has responded well. A few days after treatment her visual acuity has improved to 20/60 OD; there was no anterior segment inflammation OU, and decreased vitreous cell OU. Disc edema was improved. The large placoid lesion in the macula of the right eye was slightly enlarged, but more granular in appearance without a distinct yellowish border, and the smaller lesions SN had dissipated. OCT showed resolution of the subfoveal fluid and an improved appearance of the outer retina and RPE layer.

Imaging device: Optos CA

Condition/keywords: acute syphilitic posterior placoid chorioretinitis

Dec 19 2020 by John S. King, MD

44-year-old white female seen over the weekend complaining of a "spot" in her vision centrally OD for three days. She was referred over by another eye doctor who was concerned about a possible retinal detachment vs ARN in that eye. Her past medical history includes adrenal insufficiency for which she takes a low dose of hydrocortisone, thyroxine (post thyroidectomy), plaquenil (inflammatory arthritis). She is divorced with one partner and denies any IVDU. Va 20/200 OD and 20/20 OS, IOP 12 OU, pupils mydriatic post gtts (light desaturation OD). There was 1+ A/C cell OD, O/W unremarkable anterior segment OU; in the posterior segment OD there was 1+ vitritis with a diffusely swollen optic disc and a large yellowish placoid lesion in the macula with yellowish border and extended out past the arcades inferiorly, as well as another lesion smaller in the IN periphery. There was a trace vitreous cell OS with a large, granular placoid lesion nasally. The OCT (see above) shows mild subfoveal fluid with nodular areas in the RPE and some overlying irregular architecture of the outer retina. Syphilis was a concern at this point. She denied any hand or foot rash, and said that she was recently working on the house, and her hands were dried out. There did appear to be a rash on the hand, and later learned that she had a rash on the soles of her feet. She was sent to ED for a work-up and her syphilis IgG was positive and VDRL 1:128, and negative for HIV. She was started on a course IV Penicillin (40mg PO steroid two days after tx started). She has responded well. A few days after treatment her visual acuity has improved to 20/60 OD; there was no anterior segment inflammation OU, and decreased vitreous cell OU. Disc edema was improved. The large placoid lesion in the macula of the right eye was slightly enlarged, but more granular in appearance without a distinct yellowish border, and the smaller lesions SN had dissipated. OCT showed resolution of the subfoveal fluid and an improved appearance of the outer retina and RPE layer.

Imaging device: Zeiss Cirrus

Condition/keywords: acute syphilitic posterior placoid chorioretinitis, syphilis

Dec 19 2020 by John S. King, MD

44-year-old white female seen over the weekend complaining of a "spot" in her vision centrally OD for three days. She was referred over by another eye doctor who was concerned about a possible retinal detachment vs ARN in that eye. Her past medical history includes adrenal insufficiency for which she takes a low dose of hydrocortisone, thyroxine (post thyroidectomy), plaquenil (inflammatory arthritis). She is divorced with one partner and denies any IVDU. Va 20/200 OD and 20/20 OS, IOP 12 OU, pupils mydriatic post gtts (light desaturation OD). There was 1+ A/C cell OD, O/W unremarkable anterior segment OU; in the posterior segment OD there was 1+ vitritis with a diffusely swollen optic disc and a large yellowish placoid lesion in the macula with yellowish border and extended out past the arcades inferiorly, as well as another lesion smaller in the IN periphery. There was a trace vitreous cell OS with a large, granular placoid lesion nasally. The OCT via the lesion (see above) shows nodular areas in the RPE and some overlying disruption of EZ and outer retina. Syphilis was a concern at this point. She denied any hand or foot rash, and said that she was recently working on the house, and her hands were dried out. There did appear to be a rash on the hand, and later learned that she had a rash on the soles of her feet. She was sent to ED for a work-up and her syphilis IgG was positive and VDRL 1:128, and negative for HIV. She was started on a course IV Penicillin (40mg PO steroid two days after tx started). She has responded well. A few days after treatment her visual acuity has improved to 20/60 OD; there was no anterior segment inflammation OU, and decreased vitreous cell OU. Disc edema was improved. The large placoid lesion in the macula of the right eye was slightly enlarged, but more granular in appearance without a distinct yellowish border, and the smaller lesions SN had dissipated. OCT showed resolution of the subfoveal fluid and an improved appearance of the outer retina and RPE layer.

Imaging device: Zeiss Cirrus

Condition/keywords: acute syphilitic posterior placoid chorioretinitis, syphilis

Dec 19 2020 by John S. King, MD

44-year-old white female seen over the weekend complaining of a "spot" in her vision centrally OD for three days. She was referred over by another eye doctor who was concerned about a possible retinal detachment vs ARN in that eye. Her past medical history includes adrenal insufficiency for which she takes a low dose of hydrocortisone, thyroxine (post thyroidectomy), plaquenil (inflammatory arthritis). She is divorced with one partner and denies any IVDU. Va 20/200 OD and 20/20 OS, IOP 12 OU, pupils mydriatic post gtts (light desaturation OD). There was 1+ A/C cell OD, O/W unremarkable anterior segment OU; in the posterior segment OD there was 1+ vitritis with a diffusely swollen optic disc and a large yellowish placoid lesion in the macula with yellowish border and extended out past the arcades inferiorly, as well as another lesion smaller in the IN periphery. There was trace vitreous cell OS, mild disc edema, and a large, granular placoid area nasally that appeared to be granulated. The OCT showed mild subfoveal fluid with nodular areas in the RPE and some overlying irregular architecture of the outer retina. Syphilis was a concern at this point. She denied any hand or foot rash, and said that she was recently working on the house, and her hands were dried out. There did appear to be a rash on the hand, and later learned that she had a rash on the soles of her feet. She was sent to ED for a work-up and her syphilis IgG was positive and VDRL 1:128, and negative for HIV. She was started on a course IV Penicillin (40mg PO steroid two days after tx started). She has responded well. A few days after treatment her visual acuity has improved to 20/60 OD; there was no anterior segment inflammation OU, and decreased vitreous cell OU. Disc edema was improved. The large placoid lesion in the macula of the right eye was slightly enlarged, but more granular in appearance without a distinct yellowish border, and the smaller lesions SN had dissipated (See Image). OCT showed resolution of the subfoveal fluid and an improved appearance of the outer retina and RPE layer.

Photographer: Ashley Seiger

Imaging device: Optos CA

Condition/keywords: acute syphilitic posterior placoid chorioretinitis

Dec 19 2020 by John S. King, MD

44-year-old white female seen over the weekend complaining of a "spot" in her vision centrally OD for three days. She was referred over by another eye doctor who was concerned about a possible retinal detachment vs ARN in that eye. Her past medical history includes adrenal insufficiency for which she takes a low dose of hydrocortisone, thyroxine (post thyroidectomy), plaquenil (inflammatory arthritis). She is divorced with one partner and denies any IVDU. Va 20/200 OD and 20/20 OS, IOP 12 OU, pupils mydriatic post gtts (light desaturation OD). There was 1+ A/C cell OD, O/W unremarkable anterior segment OU; in the posterior segment OD there was 1+ vitritis with a diffusely swollen optic disc and a large yellowish placoid lesion in the macula with yellowish border and extended out past the arcades inferiorly, as well as another lesion smaller in the IN periphery. There was trace vitreous cell OS, mild disc edema, and a large, granular placoid area nasally that appeared to be granulated. The OCT showed mild subfoveal fluid with nodular areas in the RPE and some overlying irregular architecture of the outer retina. Syphilis was a concern at this point. She denied any hand or foot rash, and said that she was recently working on the house, and her hands were dried out. There did appear to be a rash on the hand, and later learned that she had a rash on the soles of her feet. She was sent to ED for a work-up and her syphilis IgG was positive and VDRL 1:128, and negative for HIV. She was started on a course IV Penicillin (40mg PO steroid two days after tx started). She has responded well. A few days after treatment her visual acuity has improved to 20/60 OD; there was no anterior segment inflammation OU, and decreased vitreous cell OU. Disc edema was improved. The large placoid lesion in the macula of the right eye was slightly enlarged, but more granular in appearance without a distinct yellowish border, and the smaller lesions SN had dissipated (See Image). OCT showed resolution of the subfoveal fluid and an improved appearance of the outer retina and RPE layer.

Photographer: Ashley Seiger

Imaging device: Optos CA

Condition/keywords: acute syphilitic posterior placoid chorioretinitis, syphilis

Dec 19 2020 by John S. King, MD

44-year-old white female seen over the weekend complaining of a "spot" in her vision centrally OD for three days. She was referred over by another eye doctor who was concerned about a possible retinal detachment vs ARN in that eye. Her past medical history includes adrenal insufficiency for which she takes a low dose of hydrocortisone, thyroxine (post thyroidectomy), plaquenil (inflammatory arthritis). She is divorced with one partner and denies any IVDU. Va 20/200 OD and 20/20 OS, IOP 12 OU, pupils mydriatic post gtts (light desaturation OD). There was 1+ A/C cell OD, O/W unremarkable anterior segment OU; in the posterior segment OD there was 1+ vitritis with a diffusely swollen optic disc and a large yellowish placoid lesion in the macula with yellowish border and extended out past the arcades inferiorly, as well as another lesion smaller in the IN periphery. There was trace vitreous cell OS, mild disc edema, and a large, granular placoid area nasally that appeared to be granulated (See Image). The OCT showed mild subfoveal fluid with nodular areas in the RPE and some overlying irregular architecture of the outer retina. Syphilis was a concern at this point. She denied any hand or foot rash, and said that she was recently working on the house, and her hands were dried out. There did appear to be a rash on the hand, and later learned that she had a rash on the soles of her feet. She was sent to ED for a work-up and her syphilis IgG was positive and VDRL 1:128, and negative for HIV. She was started on a course IV Penicillin (40mg PO steroid two days after tx started).... She has responded well. A few days after treatment her visual acuity has improved to 20/60 OD; there was no anterior segment inflammation OU, and decreased vitreous cell OU. Disc edema was improved. The large placoid lesion in the macula of the right eye was slightly enlarged, but more granular in appearance without a distinct yellowish border, and the smaller lesions SN had dissipated. OCT showed resolution of the subfoveal fluid and an improved appearance of the outer retina and RPE layer.

Imaging device: Optos CA

Condition/keywords: acute syphilitic posterior placoid chorioretinitis, syphilis

Dec 19 2020 by John S. King, MD

44-year-old white female seen over the weekend complaining of a "spot" in her vision centrally OD for three days. She was referred over by another eye doctor who was concerned about a possible retinal detachment vs ARN in that eye. Her past medical history includes adrenal insufficiency for which she takes a low dose of hydrocortisone, thyroxine (post thyroidectomy), Plaquenil (inflammatory arthritis). She is divorced with one partner and denies any IVDU. Va 20/200 OD and 20/20 OS, IOP 12 OU, pupils mydriatic post gtts (light desaturation OD). There was 1+ A/C cell OD, O/W unremarkable anterior segment OU; in the posterior segment OD there was 1+ vitritis with a diffusely swollen optic disc and a large yellowish placoid lesion in the macula with yellowish border and extended out past the arcades inferiorly, as well as another lesion smaller in the IN periphery, and two possible smaller spots SN (See Photo above). There was a trace vitreous cell OS with a large, granular placoid lesion nasally. The OCT showed mild subfoveal fluid with nodular areas in the RPE and some overlying irregular architecture of the outer retina. Syphilis was a concern at this point. She denied any hand or foot rash, and said that she was recently working on the house, and her hands were dried out. There did appear to be a rash on the hand, and later learned that she had a rash on the soles of her feet. She was sent to ED for a work-up and her syphilis IgG was positive and VDRL 1:128, and negative for HIV. She was started on a course IV Penicillin (40mg PO steroid two days after tx started). She has responded well. A few days after treatment her visual acuity has improved to 20/60 OD; there was no anterior segment inflammation OU, and decreased vitreous cell OU. Disc edema was improved. The large placoid lesion in the macula of the right eye was slightly enlarged, but more granular in appearance without a distinct yellowish border, and the smaller lesions SN had dissipated. OCT showed resolution of the subfoveal fluid and an improved appearance of the outer retina and RPE layer.

Imaging device: Optos CA

Condition/keywords: acute syphilitic posterior placoid chorioretinitis, syphilis

Dec 19 2020 by John S. King, MD

44-year-old white female seen over the weekend complaining of a "spot" in her vision centrally OD for three days. She was referred over by another eye doctor who was concerned about a possible retinal detachment vs ARN in that eye. Her past medical history includes adrenal insufficiency for which she takes a low dose of hydrocortisone, thyroxine (post thyroidectomy), plaquenil (inflammatory arthritis). She is divorced with one partner and denies any IVDU. Va 20/200 OD and 20/20 OS, IOP 12 OU, Pupils mydriatic post gtts (light desaturation OD). There was 1+ A/C cell OD, O/W unremarkable anterior segment OU; in the posterior segment OD there was 1+ vitritis with a diffusely swollen optic disc and a large yellowish placoid lesion in the macula with yellowish border and extended out past the arcades inferiorly, as well as another lesion smaller in the IN periphery. There was trace vitreous cell OS, mild disc edema, and a large, granular placoid area nasally that appeared to be granulated. The OCT showed mild subfoveal fluid with nodular areas in the RPE and some overlying irregular architecture of the outer retina. Syphilis was a concern at this point. She denied any hand or foot rash, and said that she was recently working on the house, and her hands were dried out. There did appear to be a rash on the hand, and later learned that she had a rash on the soles of her feet. She was sent to ED for a work-up and her syphilis IgG was positive and VDRL 1:128, and negative for HIV. She was started on a course IV Penicillin (40mg PO steroid two days after tx started). She has responded well. A few days after treatment her visual acuity has improved to 20/60 OD; there was no anterior segment inflammation OU, and decreased vitreous cell OU. Disc edema was improved. The large placoid lesion in the macula of the right eye was slightly enlarged, but more granular in appearance without a distinct yellowish border, and the smaller lesions SN had dissipated. OCT showed resolution of the subfoveal fluid and an improved appearance of the outer retina and RPE layer (See Image).

Imaging device: Zeiss Cirrus

Condition/keywords: acute syphilitic posterior placoid chorioretinitis, syphilis

Nov 22 2020 by Shawn Sell

58-year-old homeless male presenting with 2 weeks of bilateral eye redness and photosensitivity found to have panuveitis with a positive VDRL CSF and RPR titer of 1:512 with acute syphilitic posterior placoid chorioretinitis.

Photographer: Eastern Virginia Medical School

Imaging device: Optos

Condition/keywords: acute syphilitic posterior placoid chorioretinitis, neurosyphilis

Nov 22 2020 by Shawn Sell

58-year-old homeless male presenting with 2 weeks of bilateral eye redness and photosensitivity found to have panuveitis with a positive VDRL CSF and RPR titer of 1:512 with acute syphilitic posterior placoid chorioretinitis.

Photographer: Eastern Virginia Medical School

Imaging device: Optos

Condition/keywords: acute syphilitic posterior placoid chorioretinitis

Oct 2 2020 by David L Kilpatrick, MD

22-year-old female presented with painless blurry vision OD > OS for one week. On exam, she exhibited moderate vitritis, papillitis and broad placoid chorioretinitis OD and multifocal placoid peripheral chorioretinitis OS (without vitritis or papillitis). The anterior segment was unremarkable OU. Serum RPR and confirmatory treponemal Ab were both positive. Neuroimaging and CSF studies were unremarkable. A 2 week course of IV penicillin was initiated. The placoid lesions had resolved five days after beginning treatment.

Photographer: Mississippi Retina Associates

Condition/keywords: acute syphilitic posterior placoid chorioretinitis, syphilis