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By McGill University Health Centre
The MUHC-McGill University
Co-author(s): Sabrina Bergeron, P. Zoroquiain, E. Esposito, S. Corredor Casas, P. Logan, A. N. Odashiro, Miguel N. Burnier, Paulina García de Alba Graue, McGill University Health Center-McGill University Ocular Pathology & Translational Research Laboratory - Uploaded on May 18, 2020.
- Last modified by Caroline Bozell on May 19, 2020.
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- Appears in
- VogtKoyanagiHarada Disease
- Condition/keywords
- Vogt-Koyanagi-Harada, Dalen-Fuchs nodules, enucleation
- Description
- VKH disease is an autoimmune condition that causes bilateral chronic granulomatous panuveitis, and extraocular manifestations in the central nervous system, auditory system, and integument. VKH disease is twice as prevalent in women than men, and is believed to be associated with specific human leukocyte antigen (HLA) types, suggesting a possible hereditary component. The exact cause of VKH disease, however, remains unclear. Image (B) shows several aggregate RPE cells and histiocytes, called Dalen–Fuchs nodules (arrows)
