Vogt-Koyanagu-Harada (VKH) Disease

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File number: 55907


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    • By McGill University Health Centre
      The MUHC-McGill University
      Co-author(s): Sabrina Bergeron, P. Zoroquiain, E. Esposito, S. Corredor Casas, P. Logan, A. N. Odashiro, Miguel N. Burnier, Paulina GarcĂ­a de Alba Graue, McGill University Health Center-McGill University Ocular Pathology & Translational Research Laboratory
    • Uploaded on May 18, 2020.
    • Last modified by Caroline Bozell on May 19, 2020.
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    Appears in
    VogtKoyanagiHarada Disease
    Condition/keywords
    Vogt-Koyanagi-Harada, scleral buckle
    Description
    VKH disease is an autoimmune condition that causes bilateral chronic granulomatous panuveitis, and extraocular manifestations in the central nervous system, auditory system, and integument. VKH disease is twice as prevalent in women than men, and is believed to be associated with specific human leukocyte antigen (HLA) types, suggesting a possible hereditary component. The exact cause of VKH disease, however, remains unclear. In (A), an enucleation specimen shows a retinal detachment and a scleral buckle (*).

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