Fluorescein Leakage from Choroidal Neovascularization Due to Age-Related Macular Degeneration in Absence of Abnormality on Spectral-Domain Optical Coherence Tomography

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By Neil M. Bressler, MD
Johns Hopkins University
Co-author(s): Voraporn Chaikitmongkol, MD
Uploaded on Feb 11, 2013.
Last modified by Caroline Bozell on Feb 12, 2013.
Reviewed by Caroline Bozell

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Appears in: Miscellaneous
Condition/keywords: choroidal neovascularization (CNV), age-related macular degeneration (AMD)
Imaging device: Fundus camera
Description: During monitoring of anti-vascular endothelial growth factor therapy in neovascular age-related macular degeneration (Fig A), 10% of active CNV with fluorescein angiographic leakage (Fig B - D) may show the absence of fluid in SD-OCT1 (Fig E), as shown in this case. Reference 1 Khurana RN, Dupas B, Bressler NM. Agreement of time-domain and spectral-domain optical coherence tomography with fluorescein leakage from choroidal neovascularization. Ophthalmology 2010;117:1376-1380.