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By Lancaster Course in Ophthalmology
1980 - Uploaded on Feb 26, 2019.
- Last modified by Caroline Bozell on Mar 7, 2019.
- Rating
- Appears in
- Unit 09 Pathology of the Retina
- Condition/keywords
- Type III systemic mucopolysaccharidosis, Sanfilippo syndrome, mucopolysaccharidoses
- Description
- Type III systemic mucopolysaccharidosis (San Filippo syndrome). The retinal ganglion cells are distended (upper left) and contain mucopolysaccharide (middle, top: colloidal iron), lipid (upper right: Sudan-black B). Phase-contrast (lower left) shows numerous vacuoles, and by electron microscopy (lower right) there are numerous inclusions of the fibrillogranular and multimembranous types.
