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By Vicente Nicanor Mancilla Guerrero
Universidad Austral de Chile - Uploaded on Aug 10, 2026.
- Last modified by Joshua Friedman on Aug 11, 2026.
- Rating
- Appears in
- Miscellaneous
- Condition/keywords
- optic neuritis, paraneoplastic
- Photographer
- Vicente Mancilla G, Medical technologist specialized in ophthalmology
- Imaging device
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Fundus camera
Compass Centervue iCare - Description
- Male patient diagnosed with paraneoplastic optic neuritis of the left eye. This is a rare phenomenon, usually associated with small-cell carcinomas. It is believed that tumor-associated antigens such as CRMP-5 IgL generate antibodies that cross-react with neuronal and glial proteins; aside from neuritis, they can trigger the neuromyelitis optica spectrum. In this patient, this neuritis progressed to complete optic nerve atrophy, as this is a blind eye.
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