Cystoid macular Edema with Honeycomb Sign

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File number: 134393


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    • By Kefina Jos
      Vijayalakshme Eye Hospital
      Co-author(s): Dr.Sivaranjan R, Vijayalakshme Eye Hospital
    • Uploaded on Jul 12, 2026.
    • Last modified by Joshua Friedman on Jul 12, 2026.
    Rating
    Appears in
    Miscellaneous
    Condition/keywords
    cystoid macular edema (CME), honeycomb
    Photographer
    Sudha, Vijayalakshme Eye Hospital
    Imaging device
    Scanning laser ophthalmoscope
    Description
    A 57 year-old female presented with blurring of distant vision for past 2 months. The color fundus photography of her RE reveals abnormal foveal reflex. The macular area appears to be greyish, with central large cystic space surrounded by multiple small cystic spaces arranged in radial pattern. This pattern is influenced by the arrangement of Henle's fiber layer in which the fluid accumulates because of the breakdown in the blood retinal barrier. This anatomical configuration leads to the characteristic honeycomb appearance in cystoid macular edema.

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