Optic Disc Granuloma

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File number: 133164


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    Rating
    Appears in
    Miscellaneous
    Condition/keywords
    Tuberculosis
    Photographer
    Ms. Krishna Jeyanthi
    Imaging device
    Fundus camera
    Zeiss Clarus 500
    Description
    A 45-year-old male presented with diminished vision for one month. His Mantoux test was negative, but as steroids worsened the condition, quantiferon TB was advised and it returned positive. He was started on anti-tuberculosis treatment (ATT). Oral steroids were reintroduced after one week of ATT. Optic disc granulomas can arise from direct invasion of the optic nerve or may represent hypersensitivity reaction to tuberculous antigens. The pathogenesis involves infiltration of immune cells, leading to formation of a granulomatous structure that disrupts normal architecture and function of the optic disc. Steroids with ATT facilitated regression of granulomatous lesion.

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