Proliferative Vitreoretinopathy

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    • By Marcelo Zas, MD PhD
      Hospital de Clinicas-University of Buenos Aires
      Co-author(s): Guido Bregliano MD, Luciano Scorsetti MD, Mariano Cotic MD, Adriana Nieva MD, Julieta Fourcade MD, Sofia Ghigliotti MD, Marcos Mendaro MD, Pablo Chiaradia MD PhD
    • Uploaded on Jun 9, 2024.
    • Last modified by Joshua Friedman on Jun 17, 2024.
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    Appears in
    Miscellaneous
    Condition/keywords
    proliferative vitreoretinopathy (PVR)
    Photographer
    Luciano Scorsetti MD
    Description
    We present a case of a 20-year-old patient who underwent surgery for congenital cataract when he was born and 20 years after he developed a retinal detachment with proliferative vitreoretinopathy. Proliferative vitreoretinopathy (PVR), a major complication of rhegmatogenous retinal detachment (RRD), is an abnormal process whereby proliferative, contractile cellular membranes form in the vitreous and on both sides of the retina, resulting in tractional retinal detachment with fixed retinal folds. PVR arises in an estimated 5-10% of RRD cases, and therefore represents a major complication of retinal detachment. The best treatment of PVR is its prevention. Clinical factors associated with increased risk of PVR include: • Chronic RRD • 2 o more horseshoe retinal tears and RRD exposing three-disc diameters or more of RPE • RD associated with giant retinal • RD associated with choroidal detachment • Ocular Trauma • RRD associated with vitreous hemorrhage • Aphakia and RRD • Failure of previous surgery or multiple retinal surgeries • Aggressive retinitis, etc.

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