Search results (63 results)

  • Retinoblastoma - Regressed

    May 3 2013 by Suber S. Huang, MD, MBA, FASRS

    24-year-old male status post radiation for retinoblastoma with secondary metastatic carcinoma.

    Imaging device: Retina Diseases Imaging Analysis Reading Center

    Condition/keywords: endophytic tumor growth, intraocular tumor, macular lesion, radiotherapy, retinoblastoma

  • Right Macular Lesion

    Feb 3 2014 by Maurice F. Rabb

    Male patient with lesion in the right macula. It appears he has a small area of epiretinal or intraretinal fibrotic or fibrotic tissue wiht nonperfusion encircled by telangienctasis.

    Condition/keywords: macular lesion, retinal telangiectasia

  • Right Macular Lesion

    Feb 3 2014 by Maurice F. Rabb

    Male patient with lesion in the right macula. It appears he has a small area of epiretinal or intraretinal fibrotic or fibrotic tissue wiht nonperfusion encircled by telangienctasis.

    Condition/keywords: macular lesion, retinal telangiectasia

  • Best Vitelliform Macular Dystrophy

    Dec 10 2020 by McGill University Health Centre

    Postmortem eyes from 101-year-old female. Past clinical history includes a poor vision for many years due to macular degeneration. The last visual acuity test recorded 6/15 OD and 6/6 OS. IOP 14 and 18 torr OS. Histopathology: Disclosed and yellow 2x2mm macular lesion. Microscopic examination: elevated placoid macular lesion with overlying pigment granules. Electron microscopy examination: pigment granules with abundant lipofuscin and melanolysosomes, photoreceptor cells markedly attenuated (less degenerated at the periphery) Numerous calcified drusen throughout the retina particularly in the posterior pole. RPE lipofuscin content is elevated in Best’s dystrophy. The extractability of the PRE lipofuscin fluorophores is reduced (it is normal during senescence). The defect in Best’s dystrophy accelerates this age related change in lipofuscin.

    Condition/keywords: Best vitelliform macular dystrophy (BVMD), fundus photograph

  • Best Vitelliform Macular Dystrophy

    Dec 10 2020 by McGill University Health Centre

    Postmortem eyes from 101-year-old female. Past clinical history includes a poor vision for many years due to macular degeneration. The last Visual acuity test recorded 6/15 OD and 6/6 OS. IOP 14 and 18 torr OS. Histopathology: Disclosed and yellow 2x2mm macular lesion. Microscopic examination: elevated placoid macular lesion with overlying pigment granules. Electron microscopy examination: pigment granules with abundant lipofuscin and melanolysosomes, photoreceptor cells markedly attenuated (less degenerated at the periphery) Numerous calcified drusen throughout the retina particularly in the posterior pole. RPE lipofuscin content is elevated in Best’s dystrophy. The extractability of the PRE lipofuscin fluorophores is reduced (it is normal during senescence). The defect in Best’s dystrophy accelerates this age related change in lipofuscin.

    Condition/keywords: Best vitelliform macular dystrophy (BVMD), histopathology, pathology

  • Best Vitelliform Macular Dystrophy

    Dec 10 2020 by McGill University Health Centre

    Postmortem eyes from 101-year-old female. Past clinical history includes a poor vision for many years due to macular degeneration. The last visual acuity test recorded 6/15 OD and 6/6 OS. IOP 14 and 18 torr OS. Histopathology: Disclosed and yellow 2x2mm macular lesion. Microscopic examination: elevated placoid macular lesion with overlying pigment granules. Electron microscopy examination: pigment granules with abundant lipofuscin and melanolysosomes, photoreceptor cells markedly attenuated (less degenerated at the periphery) Numerous calcified drusen throughout the retina particularly in the posterior pole. RPE lipofuscin content is elevated in Best’s dystrophy. The extractability of the PRE lipofuscin fluorophores is reduced (it is normal during senescence). The defect in Best’s dystrophy accelerates this age related change in lipofuscin.

    Condition/keywords: Best vitelliform macular dystrophy (BVMD), histopathology, pathology

  • Best Vitelliform Macular Dystrophy

    Dec 10 2020 by McGill University Health Centre

    Postmortem eyes from 101-year-old female. Past clinical history includes a poor vision for many years due to macular degeneration. The last visual acuity test recorded 6/15 OD and 6/6 OS. IOP 14 and 18 torr OS. Histopathology: Disclosed and yellow 2x2mm macular lesion. Microscopic examination: elevated placoid macular lesion with overlying pigment granules. Electron microscopy examination: pigment granules with abundant lipofuscin and melanolysosomes, photoreceptor cells markedly attenuated (less degenerated at the periphery) Numerous calcified drusen throughout the retina particularly in the posterior pole. RPE lipofuscin content is elevated in Best’s dystrophy. The extractability of the PRE lipofuscin fluorophores is reduced (it is normal during senescence). The defect in Best’s dystrophy accelerates this age related change in lipofuscin.

    Condition/keywords: Best vitelliform macular dystrophy (BVMD), histopathology, pathology

  • Central Macular Lesion, Choroidal Hemangioma, Staphyloma

    Jul 11 2013 by Jerald A. Bovino, MD

    No history.

    Condition/keywords: central vascular lesion, staphyloma

  • Choroidal Osteoma

    Apr 17 2025 by Gustavo Uriel Fonseca Aguirre

    Top (B-mode): The longitudinal scan reveals a hyperechoic, flat, and well-demarcated macular lesion with posterior acoustic shadowing, pathognomonic for choroidal osteoma. Bottom (A-mode): Standardized tracing shows a tall initial spike (100% reflectivity) at the tumor surface with rapid decay to acoustic silence, confirming sound absorption by calcified tissue. This pattern remains unchanged at variable gain settings.

    Photographer: Gustavo U. Fonseca Aguirre, Hospital Conde de Valenciana, Ciudad de México

    Condition/keywords: choroidal osteoma, macular choroidal osteoma

  • Choroidal Osteoma

    Jun 2 2018 by awaneesh m upadhyay, MBBS, DNB

    23-year-old patient's fundus photograph having complaints of defective vision, metamorphosia over 6 months shows yellow orange elevated well defined submacular lesion with normal overlying retinal vessels and normal disc . Vision left eye is 20/80.

    Photographer: Hiteshwar Saikia

    Condition/keywords: macular choroidal osteoma

  • Combined Hamartoma of the Retina and Retinal Pigment Epithelium (CHRRPE)

    Jan 21 2020 by Pierre-Henry Gabrielle, MD

    Coupled OCT B-scan and IR imaging of a 17-year-old man with Combined hamartomas of the retina and retinal pigment epithelium (CHRRPE) at the posterior pole of the left eye. One can see a highly reflective elevated macular lesion with hyporeflective shadowing of the underlying tissue and obscuration of the normal retinal layers.

    Photographer: Pierre-Henry Gabrielle, Ophthalmology department, Dijon University Hospital, France

    Imaging device: Heidelberg Spectralis

    Condition/keywords: combined hamartoma, optical coherence tomography (OCT)

  • Combined Hamartoma of the Retina and Retinal Pigment Epithelium (CHRRPE)

    Jan 21 2020 by Pierre-Henry Gabrielle, MD

    Coupled OCT B-scan and IR imaging of a 17-year-old man with combined hamartomas of the retina and retinal pigment epithelium (CHRRPE) at the posterior pole of the left eye. One can see a highly reflective elevated macular lesion with hyporeflective shadowing of the underlying tissue and obscuration of the normal retinal layers.

    Photographer: Pierre-Henry Gabrielle, Ophthalmology department, Dijon University Hospital, France

    Imaging device: Heidelberg Spectralis

    Condition/keywords: combined hamartoma, optical coherence tomography (OCT)

  • Congenital Toxoplasmosis

    Aug 13 2013 by From the Collections of Thomas M. Aaberg, MD and Thomas M. Aaberg Jr., MD

    Hyper and hypo oimentedmacular lesion.

    Condition/keywords: congenital toxoplasmosis

  • Congenital Toxoplasmosis

    Aug 13 2013 by From the Collections of Thomas M. Aaberg, MD and Thomas M. Aaberg Jr., MD

    Hyper and hypo oimentedmacular lesion.

    Condition/keywords: congenital toxoplasmosis

  • Congenital Toxoplasmosis

    Aug 13 2013 by From the Collections of Thomas M. Aaberg, MD and Thomas M. Aaberg Jr., MD

    Hyper and hypo oimentedmacular lesion.

    Condition/keywords: congenital toxoplasmosis

  • Congenital Toxoplasmosis

    Aug 13 2013 by From the Collections of Thomas M. Aaberg, MD and Thomas M. Aaberg Jr., MD

    Hyper and hypo oimentedmacular lesion.

    Condition/keywords: congenital toxoplasmosis

  • Congenital Toxoplasmosis

    Aug 13 2013 by From the Collections of Thomas M. Aaberg, MD and Thomas M. Aaberg Jr., MD

    Hyper and hypo oimentedmacular lesion.

    Condition/keywords: congenital toxoplasmosis

  • Congenital Toxoplasmosis

    Aug 13 2013 by From the Collections of Thomas M. Aaberg, MD and Thomas M. Aaberg Jr., MD

    Hyper and hypo oimentedmacular lesion.

    Condition/keywords: congenital toxoplasmosis

  • Congenital Toxoplasmosis

    Aug 13 2013 by From the Collections of Thomas M. Aaberg, MD and Thomas M. Aaberg Jr., MD

    Hyper and hypo oimentedmacular lesion.

    Condition/keywords: congenital toxoplasmosis

  • Congenital Toxoplasmosis

    Aug 13 2013 by From the Collections of Thomas M. Aaberg, MD and Thomas M. Aaberg Jr., MD

    Hyper and hypo oimentedmacular lesion.

    Condition/keywords: congenital toxoplasmosis

  • Congenital Toxoplasmosis

    Aug 13 2013 by From the Collections of Thomas M. Aaberg, MD and Thomas M. Aaberg Jr., MD

    Hyper and hypo oimentedmacular lesion.

    Condition/keywords: congenital toxoplasmosis

  • Congenital Toxoplasmosis

    Aug 13 2013 by From the Collections of Thomas M. Aaberg, MD and Thomas M. Aaberg Jr., MD

    Hyper and hypo oimentedmacular lesion.

    Condition/keywords: congenital toxoplasmosis

  • Congenital Toxoplasmosis

    Aug 13 2013 by From the Collections of Thomas M. Aaberg, MD and Thomas M. Aaberg Jr., MD

    Hyper and hypo oimentedmacular lesion.

    Condition/keywords: congenital toxoplasmosis

  • Congenital Toxoplasmosis

    Aug 13 2013 by From the Collections of Thomas M. Aaberg, MD and Thomas M. Aaberg Jr., MD

    Hyper and hypo oimentedmacular lesion.

    Condition/keywords: congenital toxoplasmosis

  • Congenital Toxoplasmosis

    Aug 13 2013 by From the Collections of Thomas M. Aaberg, MD and Thomas M. Aaberg Jr., MD

    Hyper and hypo oimentedmacular lesion.

    Condition/keywords: congenital toxoplasmosis