Search results (45 results)

  • ARMD with RPE Rip

    Oct 12 2012 by Jeffrey G. Gross, MD, FASRS

    ARMD with RPE rip, FA, showing window defect and blockage from retracted RPE layer.

    Condition/keywords: retinal pigment epithelium, retinal pigment epithelium (RPE) tear, retracted retinal pigment epithelium (RPE) layer

  • Retinitis pigmentosa AD Slide 4

    Oct 22 2012 by Ronald C. Gentile, MD

    Early fluorescein angiography revealed early hyper-fluorescence surrounding the fovea consistent with retinal pigment epithelial (RPE) depigmentation. This accentuated the contrast between the normal blockage (hypo-fluorescence) of the macular luteal pigment from the surrounding RPE window defect (hyper-fluorescence).

    Photographer: The New York Eye & Ear Infirmary Department of Medical Imaging

    Condition/keywords: retinitis pigmentosa

  • CNV due to AMPPE

    Oct 16 2012 by Ratimir Lazic, MD, PhD

    FAG of 58-year-old male. In late venous phase hyperflorescence of white dots (caused by window defect) can be seen. Intensive leakage of dye in juxtafoveolar region.

    Photographer: Marko Lukic, MD

    Imaging device: Zeis Visucam Lite 2

    Condition/keywords: acute posterior multifocal placoid pigment epitheliopathy (APMPPE), choroidal neovascularization (CNV)

  • Adenocarcinoma Arising from CHRPE

    Sep 17 2015 by Marc C. Peden, MD

    49-year-old female referred for presumed ocular melanoma. On examination was noted to have darkly pigmented lesion in the temporal retina of left eye. Lesion had characteristic scalloped edges with central lacunae, however, on ultrasonography was noted to have 1.8mm of elevation with high internal reflectivity. IVFA shows absence of dual circulation with areas of window defect. Findings were consistent with those described by Shields et al., in their April 2001 article in Archives of Ophthalmology.

    Photographer: Janet Traynom

    Imaging device: Optos P200MA

    Condition/keywords: adenocarcinoma arising from CHRPE

  • Pattern Macular Dystrophy

    Oct 16 2012 by Ratimir Lazic, MD, PhD

    FAG image of a 76-year-old female. In early venous phase window defect in fovea can be seen.

    Photographer: Marko Lukic, MD

    Imaging device: Zeis Visucam Lite 2

    Condition/keywords: fundus photograph, retinal pigment epithelium (RPE) defect

  • Chronic Central Serous Chorioretinopathy

    Oct 31 2012 by Lihteh Wu, MD

    FA frame showing a hyperfluorescent window defect in a gutter pattern extending down from the posterior.

    Condition/keywords: central serous chorioretinopathy (CSCR)

  • Central areolar atrophy

    May 2 2013 by Henry J. Kaplan, MD

    Fluorescein angiogram demonstrates early hyperfluorescence due to window defect; the patient is young with GA like lesion and vision of 20/200 which is compatible with central areolar atrophy#1

    Condition/keywords: central areolar choroidal dystrophy (CACD)

  • Pattern Dystrophy

    Aug 7 2013 by From the Collections of Thomas M. Aaberg, MD and Thomas M. Aaberg Jr., MD

    Fluoresceing angiography in the early laminar phase shows blocked fluorescence of the pigmented lesion and surrounding hyperfluorescense due to window defect.

    Condition/keywords: butterfly dystrophy, pattern macular dystrophy

  • CNV due to AMPPE

    Oct 16 2012 by Ratimir Lazic, MD, PhD

    FAG of 58-year-old male. In early venous phase hyperflorescence of white dots (caused by window defect) can be seen. Leakage of dye in juxtafoveolar region.

    Photographer: Marko Lukic, MD

    Imaging device: Zeis Visucam Lite 2

    Condition/keywords: acute posterior multifocal placoid pigment epitheliopathy (APMPPE), choroidal neovascularization (CNV)

  • Age Related Macular Degeneration - Geographic Atrophy

    May 3 2013 by Suber S. Huang, MD, MBA, FASRS

    Geographic Atrophy.

    Imaging device: Retina Diseases Imaging Reading Center

    Condition/keywords: advanced geographic atrophy, atrophic scar, atrophic spot, geographic atrophy, macula lesion, pigment epithelial atrophy, red-free, window defect

  • Age Related Macular Degeneration

    May 3 2013 by Suber S. Huang, MD, MBA, FASRS

    Age related macular degeneration.

    Condition/keywords: advanced geographic atrophy, atrophic scar, atrophic spot, geographic atrophy, macula lesion, pigment epithelial atrophy, red-free, window defect

  • Toxocara Granuloma

    Jun 4 2014 by Henry J. Kaplan, MD

    Arteriovenous phase angiogram of the same patient shows staining of the granuloma and stippling hyperfluorescence around the lesion secondary to RPE window defect. #3

    Condition/keywords: toxocara granuloma, toxocariasis

  • Cone Dystrophy

    Feb 20 2013 by From the Collections of Thomas M. Aaberg, MD and Thomas M. Aaberg Jr., MD

    FA of OS showing window defects in a circular pattern at the macula.

    Condition/keywords: bull's eye maculopathy, cone dystrophy

  • RPE Tear: Fluorescein Angiography

    May 2 2015 by Thomas A. Ciulla, MD, MBA, FASRS

    Mid Phase Fluorescein Angiogram: The scrolled and redundant RPE just temporal to the fovea blocks underlying choroidal fluorescence. The absent RPE, more temporally, results in a window defect with intense hyperfluorescence.

    Photographer: Stuart Alfred

    Condition/keywords: choroidal neovascular membrane (CNVM), retinal pigment epithelium (RPE) tear, wet age-related macular degeneration (wet AMD)

  • Chronic Central Serous Chorioretinopathy

    Oct 31 2012 by Lihteh Wu, MD

    FA frame showing a hyperfluorescent window defect in a gutter pattern. There is also a hot spot in the nasal macula.

  • Chronic CSCR - RPE Tracts

    May 4 2014 by Neha Goel, MS DNB FRCS (Glasg)

    FFA of a patient with chronic CSCR showing RPE window defects at the macula and RPE tracts running inferiorly from the peripapillary region.

    Photographer: Neha Goel

    Imaging device: Zeiss Visucam

    Condition/keywords: chronic central serous chorioretinopathy (CSCR), retinal pigment epithelium

  • RPE Hypertrophy

    Aug 8 2013 by From the Collections of Thomas M. Aaberg, MD and Thomas M. Aaberg Jr., MD

    FA of the same patient. Shows typical window defects in the lacunar area due to chorioretinal atrophy #2.

    Condition/keywords: retinal pigment epithelium (RPE) hypertrophy

  • Adenocarcinoma Arising from CHRPE

    Sep 17 2015 by Marc C. Peden, MD

    49-year-old female referred for presumed ocular melanoma. On examination was noted to have darkly pigmented lesion in the temporal retina of left eye. Lesion had characteristic scalloped edges with central lacunae, however, on ultrasonography was noted to have 1.8mm of elevation with high internal reflectivity. IVFA shows absence of dual circulation with areas of window defect. Findings were consistent with those described by Shields et al., in their April 2001 article in Archives of Ophthalmology.

    Photographer: Janet Traynom COT

    Imaging device: Optos P200MA

    Condition/keywords: adenocarcinoma arising from CHRPE

  • PPCNVM and Peripheral Drusen Seen on Optos FA

    Apr 22 2020 by John S. King, MD

    72-year-old white male c/o of distortion OS for about 2 months. 20/100 OS, normotensive, small grey-green subretinal area just temporal to the optic disc. FA shows leakage c/w a ppcnvm; there is some SR and IR leakage as well as staining of peripheral drusen and some window defects from cobblestone. Avastin was adminstered.

    Photographer: Asli Ahmed

    Imaging device: CA

    Condition/keywords: drusen, peripapillary choroidal neovascularization (PPCNVM)

  • Rubella Retinopathy

    May 2 2013 by Henry J. Kaplan, MD

    Fluorescein angiography of the same patient with rubella retinopathy demonstrates RPE window defects as hyperfluorescent areas; #3.

    Condition/keywords: rubella retinopathy

  • Polypoidal Chroidal Vasculopathy

    Sep 21 2018 by Dhaivat Shah

    A 40-year-old female presented with sudden onset decreased vision in right eye. BCVA: CF 1 mt. Fundus showed massive subretinal exudation with haemorrhage. EDI OCT showed notched PEDs with shallow SRF and exudation with back-shadowing. FFA shows leak with window defects. ICG shows hotspot in late phase. Polypoidal choroidal vasculopathy (PCV) is a retinal disorder characterized by the presence of aneurysmal polypoidal lesions in the choroidal vasculature, resulting in damage to the overlying retina and loss of retinal pigment epithelium. The aneurysmal dilatations, also known as polyps, may be found subfoveal, juxtafoveal, extrafoveal, peripapillary or even peripheral regions. The polypoidal lesions are best detected on indocyanine green angiography as hotspots in late phase. The presence of choroidal polyps can lead to recurrent episodes of exudative retinal detachment, serous or hemorrhagic pigment epithelial detachment, subretinal hemorrhage and exudation. Treatment is available in form of laser/PDT along with Anti VEGF injection.

    Photographer: Miss Moupiya Das

    Condition/keywords: polypoidal choroidal vasculopathy (PCV)

  • Alports Disease

    Jul 29 2013 by H. Michael Lambert, MD

    Alports disease, macular diseases not associated with FA changes. Spotty window defects with mid peripheral lesions. Disease may represent ABNL in basement membranes. Basal laminar drusen.

    Condition/keywords: Alports disease

  • Bull's Eye

    May 2 2013 by Henry J. Kaplan, MD

    Fluorescein angiography demonstrates RPE window defects and hyperfluorescence in bull's eye maculopathy; #2.

    Condition/keywords: bull's eye maculopathy

  • Chronic CSCR Resolution With Anti-VEGF

    Jul 31 2014 by Mallika Goyal, MD

    Fluorescein of the right eye of a 55-year-old male who presented with symptoms from chronic CSCR (> 3 years) shows extensive RPE window defects and occasional areas of intense hyperfluorescence.

    Photographer: Mallika Goyal, MD, Apollo Health City, Jubilee Hills, Hyderabad-500033

    Condition/keywords: chronic central serous chorioretinopathy (CSCR)

  • Alports Disease

    Jul 29 2013 by H. Michael Lambert, MD

    Alports disease, macular diseases not associated with FA changes. Spotty window defects with mid peripheral lesions. Disease may represent ABNL in basement membranes. Basal laminar drusen.

    Condition/keywords: Alports disease