Guilherme Sturzeneker, MD, MSc » 13-Nov-2025

  • Twin Maps of Ischemia: A Fluorescein–OCT Angiography Mirror in Post-Transplant Vasculopathy

    Nov 13 2025 by Guilherme Sturzeneker, MD, MSc

    Fluorescein angiography (top) and optical coherence tomography angiography (bottom) from both eyes of a 29-year-old woman, obtained 49 days after haploidentical hematopoietic stem cell transplantation, demonstrating marked bilateral macular hypoperfusion with perivascular leakage. OCT-A confirms extensive capillary dropout in both eyes. These findings are consistent with atypical bilateral ischemic retinal vasculopathy unrelated to graft-versus-host disease. Management included oral corticosteroids and intravitreal anti-VEGF injections, with partial anatomical and functional response.

    Photographer: Patrick Oikawa, IPEPO - Instituto da Visão

    Imaging device: Intalight Dream OCT

    Condition/keywords: Fluorescein angiography, Hematopoietic stem cell transplantation, Ischemic retinal vasculopathy, Non-graft-versus-host disease, OCT Angiography, oncology