A rare case of a 45-year-old male with choroidal neovascular membrane in Familial Dominant Drusen (Doyne Honeycomb Drusen) in both eyes treated with intravitreal injections.
Nov 30 2022 by SHRADDHA ASHOK CHANDORKAR, DNB DO
A 45-year-old man presented with diminution of vision in both eyes with metamorphopsia, which was painless and gradually progressive in nature. BCVA at presentation were 6/40 and 6/36 for the right and left eye respectively. Anterior segment examination of both eyes was unremarkable. IOP were within normal limits. Fundus examination showed bilateral numerous yellowish white round closely spaced lesions extending radially from the vascular arcades till the periphery associated with an elevated grayish macular choroidal neovascular membrane (CNV) with multiple drusen in the macular area and posterior pole. Impression was Familial Dominant Drusen (Doyne Honeycomb Drusen) associated with CNVM, both eyes. Color fundus photograph and autofluorescence showed Familial Dominant Drusen with CNVM. Subsequently , the patient underwent periodic intravitreal injections of Ranibizumab in both eyes under guarded visual prognosis, for which he tolerated well.
Photographer: NATIONAL INSTITUTE OF OPHTHALMOLOGY, PUNE
Imaging device: ZEISS CLARUS
Condition/keywords: choroidal neovascular membrane (CNVM), Doyne's Honeycomb, FAMILIAL DOMINANT DRUSEN, IMIM (Online Mendelian Inheritance in Man), intravitreal injection, Malattia Leventinese