Lancaster Course in Ophthalmology » Unit 03 Granulomatous Inflammations of the Eye

Feb 19 2019 by Lancaster Course in Ophthalmology

Low- power view of sclera, choroid, and retinal pigment epithelium, show­ing diffuse chronic granulomatous inflammation in sympathetic ophthalmia ( x25).

Condition/keywords: choroid, chronic granulomatous inflammation, ophthalmia, retinal pigment epithelium, sclera

Feb 19 2019 by Lancaster Course in Ophthalmology

Higher-power view of the same sympathetic ophthalmic eye, showing giant cells and epithelioid cells (x65).

Condition/keywords: epithelioid cells, ophthalmia

Feb 19 2019 by Lancaster Course in Ophthalmology

Cluster of epithelioid cells in choroid of eye with sympathetic ophthalmia (x160).

Condition/keywords: choroid, epithelioid cells, ophthalmia

Feb 19 2019 by Lancaster Course in Ophthalmology

Serous detachment of retina overlying area of infiltrated choroid in sym­pathetic ophthalmia (x12).

Condition/keywords: choroid, serous retinal detachment

Feb 20 2019 by Lancaster Course in Ophthalmology

Low-power view showing entire eye in end stage of phacoanaphylactic endophthalmitis. Note that the lens is the central focus of pathology and is extensively resorbed. Note also the occlusion and seclusion of the pupil as well as the cyclitic membrane and total retinal detachment.

Condition/keywords: cyclitic membrane, endophthalmitis

Feb 20 2019 by Lancaster Course in Ophthalmology

Higher-power view of lens area in eye with phacoanaphylaxis ( x120). Note the zonular type granulomatous reaction and adhesion of iris.

Condition/keywords: granulomatous reaction, iris, phacoanaphylaxis

Feb 20 2019 by Lancaster Course in Ophthalmology

Phacoanaphylaxis showing residual lens material, granulomatous inflam­mation, and granulation tissue ( x25).

Condition/keywords: granulation tissue, phacoanaphylaxis

Feb 20 2019 by Lancaster Course in Ophthalmology

Destruction of choroid and retina in endophthalmitis caused by Nocardia asteroides, a bacilliform, gram-positive, acid-fast bacillus ( x65).

Condition/keywords: bacilliform, choroid, endophthalmitis, Nocardia asteroides

Feb 20 2019 by Lancaster Course in Ophthalmology

Low-power view of eye with Candida albicans endophthalmitis ( x12). Note the hypopyon and exudate in the anterior chamber and the infiltration of the iris and ciliary body with inflammatory cells.

Condition/keywords: ciliary, endophthalmitis, exudate, hypopyon, iris

Feb 20 2019 by Lancaster Course in Ophthalmology

Candida albicans involving the cornea ( x65).

Condition/keywords: cornea, endophthalmitis

Feb 20 2019 by Lancaster Course in Ophthalmology

Higher-power view of hyphae and spores of Candida albicans in Can­dida keratitis ( x160).

Condition/keywords: endophthalmitis, hyphae, keratitis, spores

Feb 20 2019 by Lancaster Course in Ophthalmology

Branching nonseptate fungi seen in ocular infection with mucormycosis ( x160).

Condition/keywords: infection, mucormycosis, non septate fungi

Feb 20 2019 by Lancaster Course in Ophthalmology

Cystoid macular change with granulomatous inflammation of choroid and retina in eye of patient with presumed histoplasmosis retinochoroiditis ( x25).

Condition/keywords: choroid, cystoid macular degeneration, granulomatous inflammation, histoplasmosis

Feb 20 2019 by Lancaster Course in Ophthalmology

Adjacent area to that in Slide 3-13, showing degenerative change and inflammatory infiltrate in presumed histoplasmosis retinochoroiditis ( x25).

Condition/keywords: histoplasmosis, inflammatory infiltrate

Feb 20 2019 by Lancaster Course in Ophthalmology

Higher-power view of choroid in presumed histoplasmosis retinocho­roiditis, showing marked epithelioid cell infiltrate ( x65).

Condition/keywords: choroid

Feb 20 2019 by Lancaster Course in Ophthalmology

Enucleated eye with Toxocara endophthalmitis, showing severe poste­rior inflammation with retinal detachment and disorganization.

Condition/keywords: endophthalmitis, enucleation, toxocariasis

Feb 20 2019 by Lancaster Course in Ophthalmology

Area of anterior segments of eye with Toxocara endophthalmitis, show­ing iris infiltration by inflammatory cells, ectropion uveae, and angle closed by anterior synechiae ( x12).

Condition/keywords: anterior synechiae, ectropion uveae, endophthalmitis, iris, toxocariasis

Feb 20 2019 by Lancaster Course in Ophthalmology

Low-power view of eye enucleated with sarcoid uveitis. Note the thick­ening of the choroid and iris.

Condition/keywords: choroid, iris, sarcoid

Feb 20 2019 by Lancaster Course in Ophthalmology

View of iris and ciliary body in eye with sarcoid uveitis ( x12). Note the inflammatory cell infiltration of these structures.

Condition/keywords: ciliary, iris, sarcoid

Feb 20 2019 by Lancaster Course in Ophthalmology

Higher-power view of ciliary body of eye shown in Slides 3-19 and 3-20 reveals presence of epithelioid and giant cells ( x65).

Condition/keywords: ciliary, epithelioid cells, giant cell

Feb 20 2019 by Lancaster Course in Ophthalmology

View of choroid in eye with sarcoid uveitis, lymphocytes, and epithelioid cells with extension to sclera and degenerative changes in retinal pigment epithelium ( x65) .

Condition/keywords: choroid, epithelioid cells, epithelium, lymphocytes, sarcoid, sclera

Feb 20 2019 by Lancaster Course in Ophthalmology

Conjunctival nodule removed from lower fornix of patient with sarcoid. A discrete pattern of granulomatous inflammation is evident ( x12).

Condition/keywords: conjunctival nodule, granulomatous inflammation, lower fornix, sarcoid

Feb 20 2019 by Lancaster Course in Ophthalmology

Higher-power view showing noncaseating tubercle with Langhans' giant cells ( x65).

Condition/keywords: Langhans giant cell, noncaseating tubercle

Feb 20 2019 by Lancaster Course in Ophthalmology

Lacrimal gland involved with granulomatous inflammation in patient with sarcoid. Note the discrete pattern.

Condition/keywords: granulomatous inflammation, lacrimal glands, sarcoid

Feb 20 2019 by Lancaster Course in Ophthalmology

Higher-power view of Slide 3-25, showing epithelioid and giant cells admixed with epithelioid and plasma cells ( x25).

Condition/keywords: epithelioid cells, giant cell, plasma cells

Feb 20 2019 by Lancaster Course in Ophthalmology

Low-power view of chalazion. Note the proximity of the inflammation to the meibomian glands.

Condition/keywords: chalazion, inflammation, meibomian glands

Feb 20 2019 by Lancaster Course in Ophthalmology

Area of chalazion showing lipid droplets represented by empty spaces and predominantly chronic inflammation.

Condition/keywords: chalazion, chronic inflammation, lipid

Feb 20 2019 by Lancaster Course in Ophthalmology

Pyogenic granuloma which frequently follows chalazion ( x65). In spite of its name it is neither pyogenic nor a granuloma. Note the profusion of newly formed blood vessels, inflammatory cells, and connective tissue.

Condition/keywords: chalazion, granuloma

Feb 20 2019 by Lancaster Course in Ophthalmology

Low-power view of eye with Vogt-Koyanagi-Harada disease. Note the uveal infiltration.

Condition/keywords: uveal infiltration, Vogt-Koyanagi-Harada

Feb 20 2019 by Lancaster Course in Ophthalmology

Higher-power view of choroid in Vogt-Koyanagi-Harada disease ( x65). Note the infiltration of the choroid. In contrast to sympathetic ophthalmia, there is no sparing of the choriocapillaris, and there is destruction of the retinal pigment epithelium.

Condition/keywords: choriocapillaris, choroid, ophthalmia, retinal pigment epithelium, Vogt-Koyanagi-Harada