Fingolimob Associated Macular Edema (FAME)?

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File number: 30064


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    Rating
    Appears in
    Presumptive FAME
    Condition/keywords
    macular edema, Gilenya, cystoid macular edema (CME)
    Photographer
    Kay Dalby
    Imaging device
    Fundus camera
    Optos CA
    Description
    60 year old Caucasian female with two week history of decreased vision in the left eye. Background history includes multiple sclerosis for which she uses Gilenya for the past five years, and no history of uveitis or recent MS relapse. Her vision in the left eye was 20/100 J5. The eye appeared overall "quiet" with the exception of rare cells in the anterior vitreous. The fundus appearance and FA can be seen in the images provided. FA shows CME with scattered focal areas of vascular leakage (mainly venous) OS only. STK was administered and neurologist was able to discontinue the Gilenya. 10 days later the CME had decreased significantly. 8 weeks later the edema had resolved as seen in the OCT images of the initial and latest appearance.

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