Representative Pattern Electroretinography Responses

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File number: 130679


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    Appears in
    Miscellaneous
    Condition/keywords
    electroretinography, pattern ERG (PERG), glaucoma
    Photographer
    Gabrielle Hallai, PhD, Cleveland Clinic Cole Eye Institute
    Description
    The pattern ERG response on the left is from a control individual with no known retinal pathology. There is a clearly discernable P50 and N95 peak. On the right, there is a representative image from a patient with end-stage glaucoma. In advanced glaucoma, there is often a lack of a clearly discernable N95 peak along with a diminished N95:P50 amplitude ratio, due to retinal ganglion cell dysfunction or degeneration. The top traces are averages from two independent trials shown on the bottom. Pattern ERG testing was completed using the Diagnosys pattern ERG protocol on a CRT monitor.

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