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RPE - Rest In Peace (RIP)
Dec 17 2025 by SHRADDHA RAJ SHRIVASTAVA
Right eye G-FAF photo of a 50 year old patient, known case of bilateral familial dominant drusens with right eye CNVM, having undergone multiple intravitreal anti-VEGF injections. Fundus autofluorescence better highlights the area of RPE tear in right eye (temporal to fovea), which shows hypoautofluorescence due to lack of RPE and its pigments which accounts for autofluorescence signal. Whereas the linear hyperautofluorescence, represents the torn bunched up retinal pigment epithelium.
Photographer: Dr. Shraddha Raj Shrivastava
Imaging device: Nidek Mirante SLO/OCT (Confocal scanning/Spectral domain OCT)
Condition/keywords: choroidal neovascular membrane (CNVM), Doyne's Honeycomb, FAMILIAL DOMINANT DRUSEN, lipid exudation, retinal pigment epithelium, RPE Rip
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RPE - Rest In Peace (RIP)
Dec 17 2025 by SHRADDHA RAJ SHRIVASTAVA
Right eye RETRO mode fundus image of a 50 year old patient, known case of bilateral familial dominant drusens with right eye CNVM, having undergone multiple intravitreal anti-VEGF injections. Among other findings, this novel imaging technique highlights the presence of an extrafoveal RPE tear - post multiple intravitreal injections.
Photographer: Dr. Shraddha Raj Shrivastava
Imaging device: Nidek Mirante SLO/OCT (Confocal scanning/Spectral domain OCT)
Condition/keywords: choroidal neovascular membrane (CNVM), Doyne's Honeycomb, FAMILIAL DOMINANT DRUSEN, lipid exudation, retinal pigment epithelium, RPE Rip
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RPE - Rest In Peace (RIP)
Dec 17 2025 by SHRADDHA RAJ SHRIVASTAVA
Multimodal imaging of Right eye of a 50 year old patient, known case of bilateral familial dominant drusens with right eye CNVM, having undergone multiple intravitreal anti-VEGF injections. The various imaging modalities highlight the presence of an extrafoveal RPE tear - post multiple intravitreal injections.
Photographer: Dr. Shraddha Raj Shrivastava
Imaging device: Nidek Mirante SLO/OCT (Confocal scanning/Spectral domain OCT)
Condition/keywords: FAMILIAL DOMINANT DRUSEN, multimodal imaging, retinal pigment epithelium, RPE-Rip
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RPE - Rest In Peace (RIP)
Dec 17 2025 by SHRADDHA RAJ SHRIVASTAVA
Right eye pseudocolor fundus photo of a 50 year old patient, known case of bilateral familial dominant drusens with right eye CNVM, having undergone multiple intravitreal anti-VEGF injections. Image shows a CDR of 0.3:1, with numerous drusens at macula with residual lipid exudation from CNVM, along the infero-temporal arcade. Temporal to the fovea, we can see a vertical hyperpigmented line corresponding to retracted and redundant torn Retinal pigment epithelium, leaving behind a well circumscribed area of depigmented fundus with bare Bruch's membrane underlying the retina, findings suggestive of an RPE tear post multiple intravitreal injections.
Photographer: Dr. Shraddha Raj Shrivastava
Imaging device: Nidek Mirante SLO/OCT (Confocal scanning/Spectral domain OCT)
Condition/keywords: choroidal neovascular membrane (CNVM), Doyne's Honeycomb, FAMILIAL DOMINANT DRUSEN, lipid exudation, retinal pigment epithelium, RPE Rip
