SHRADDHA RAJ SHRIVASTAVA » Inherited Retinal Disorders

Nov 7 2025 by SHRADDHA RAJ SHRIVASTAVA

Right eye fundus photo of a 50 year old patient, diagnosed with bilateral Pericentral variant of Retinitis Pigmentosa. True to the subtype, the pigmentation is closer to fixation. There are bony spicules like pigmentary changes and RPE atrophy seen around the macula and disc (posterior pole), just adjacent to the arcades, while the peripheral fundus appears unaffected. The macula shows severe macular atrophy and scarring. Similar changes were observed in the left eye.

Photographer: Dr. Shraddha Raj Shrivastava

Imaging device: Nidek Mirante SLO/OCT (Confocal scanning/Spectral domain OCT)

Condition/keywords: pericentral retinitis pigmentosa, retinitis pigmentosa (RP) dystrophy, Rod cone dystrophy, RP variant

Nov 7 2025 by SHRADDHA RAJ SHRIVASTAVA

Left eye Green-FAF image, of a 50 year old patient, diagnosed with bilateral Pericentral variant of Retinitis Pigmentosa. The disease is characterized by pigmentary changes closer to the macula, and an earlier involvement of central visual acuity as compared to typical RP. We can see prominent, scalloped hypoautofluorescent lesions in the pericentral region, which corresponds to areas of severe RPE atrophy and photoreceptor cell loss. Macula shows preserved background autofluorescence, with darker areas corresponding to no detectable fluorescence due to macular atrophy (loss of melanin/lipofuscin).

Photographer: Dr. Shraddha Raj Shrivastava

Imaging device: Nidek Mirante SLO/OCT (Confocal scanning/Spectral domain OCT)

Condition/keywords: ATYPICAL RETINITIS PIGMENTOSA, fundus autofluorescence (FAF), pericentral retinitis pigmentosa, RP variant